Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   C2H91_RS10585 Genome accession   NZ_CP026030
Coordinates   2131093..2132295 (+) Length   400 a.a.
NCBI ID   WP_103803371.1    Uniprot ID   -
Organism   Bacillus subtilis strain PK3_9     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2126093..2137295
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H91_RS10565 (C2H91_10575) walK 2126174..2128009 (+) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -
  C2H91_RS10570 (C2H91_10580) walH 2127999..2129366 (+) 1368 WP_032722849.1 WalRK two-component regulatory system regulator WalH -
  C2H91_RS10575 (C2H91_10585) walI 2129353..2130195 (+) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  C2H91_RS10580 (C2H91_10590) vicX 2130217..2131011 (+) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  C2H91_RS10585 (C2H91_10595) htrA 2131093..2132295 (+) 1203 WP_103803371.1 serine protease HtrC Regulator
  C2H91_RS10590 - 2132315..2132441 (+) 127 Protein_2037 hypothetical protein -
  C2H91_RS10595 (C2H91_10605) - 2132558..2132746 (+) 189 Protein_2038 ATP-binding protein -
  C2H91_RS10600 (C2H91_10610) rocR 2132728..2134113 (-) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  C2H91_RS10605 (C2H91_10615) rocD 2134351..2135556 (+) 1206 WP_108029261.1 ornithine aminotransferase -
  C2H91_RS10610 (C2H91_10620) rocE 2135779..2137182 (+) 1404 WP_003242721.1 amino acid permease -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42743.50 Da        Isoelectric Point: 5.1904

>NTDB_id=222069 C2H91_RS10585 WP_103803371.1 2131093..2132295(+) (htrA) [Bacillus subtilis strain PK3_9]
MVDYDREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALEQQQNNNGREPIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDNSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=222069 C2H91_RS10585 WP_103803371.1 2131093..2132295(+) (htrA) [Bacillus subtilis strain PK3_9]
ATGGTGGATTACGATCGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGTTAGATACGGGCG
CCTTGGAACAGCAGCAAAACAACAATGGCCGGGAACCAATCCGGACGGTGAATGTCAGTGTCAACAACGCAGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACAACTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATTCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCCTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGTGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCTGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCTGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(161-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus mitis NCTC 12261

43.264

96.5

0.417
  htrA Streptococcus gordonii str. Challis substr. CH1

41.542

100

0.417
  htrA Streptococcus pneumoniae TIGR4

45.152

82.5

0.373
  htrA Streptococcus pneumoniae D39

45.152

82.5

0.373
  htrA Streptococcus pneumoniae Rx1

45.152

82.5

0.373
  htrA Streptococcus pneumoniae R6

45.152

82.5

0.373

Multiple sequence alignment