Detailed information    

insolico Bioinformatically predicted

Overview


Name   recA   Type   Machinery gene
Locus tag   CDIF102978_RS07905 Genome accession   NZ_CP020380
Coordinates   1560261..1561307 (+) Length   348 a.a.
NCBI ID   WP_021375046.1    Uniprot ID   -
Organism   Clostridioides difficile strain DSM 102978     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1528342..1605830 1560261..1561307 within 0


Gene organization within MGE regions


Location: 1528342..1605830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CDIF102978_RS07765 (CDIF102978_01544) - 1529333..1530001 (-) 669 WP_021375051.1 YwaF family protein -
  CDIF102978_RS07770 (CDIF102978_01545) - 1530270..1530410 (+) 141 WP_021375050.1 hypothetical protein -
  CDIF102978_RS07775 (CDIF102978_01546) - 1530585..1530905 (-) 321 WP_003428248.1 MazG-like family protein -
  CDIF102978_RS07780 (CDIF102978_01547) - 1531025..1531762 (-) 738 WP_021375055.1 NAD-dependent protein deacylase -
  CDIF102978_RS07785 (CDIF102978_01548) acd 1531977..1533788 (+) 1812 WP_021375079.1 N-acetylglucosaminidase -
  CDIF102978_RS07790 (CDIF102978_01549) - 1534002..1538300 (+) 4299 WP_003428241.1 PolC-type DNA polymerase III -
  CDIF102978_RS07795 (CDIF102978_01550) rimP 1538504..1538965 (+) 462 WP_003428240.1 ribosome maturation factor RimP -
  CDIF102978_RS07800 (CDIF102978_01551) nusA 1538995..1540149 (+) 1155 WP_003428238.1 transcription termination factor NusA -
  CDIF102978_RS07805 (CDIF102978_01552) rnpM 1540156..1540437 (+) 282 WP_003419469.1 RNase P modulator RnpM -
  CDIF102978_RS07810 (CDIF102978_01553) - 1540427..1540738 (+) 312 WP_003419470.1 L7Ae/L30e/S12e/Gadd45 family ribosomal protein -
  CDIF102978_RS07815 (CDIF102978_01554) infB 1540760..1542700 (+) 1941 WP_003438306.1 translation initiation factor IF-2 -
  CDIF102978_RS07820 (CDIF102978_01555) rbfA 1542743..1543123 (+) 381 WP_021375069.1 30S ribosome-binding factor RbfA -
  CDIF102978_RS07825 (CDIF102978_01556) - 1543104..1544087 (+) 984 WP_094433833.1 DHH family phosphoesterase -
  CDIF102978_RS07830 (CDIF102978_01557) truB 1544100..1545005 (+) 906 WP_003428232.1 tRNA pseudouridine(55) synthase TruB -
  CDIF102978_RS07835 (CDIF102978_01558) - 1545136..1546065 (+) 930 WP_003438310.1 bifunctional riboflavin kinase/FAD synthetase -
  CDIF102978_RS07845 (CDIF102978_01559) rpsO 1546169..1546426 (+) 258 WP_003419491.1 30S ribosomal protein S15 -
  CDIF102978_RS07850 (CDIF102978_01560) - 1546666..1547511 (+) 846 WP_009889099.1 DegV family protein -
  CDIF102978_RS07855 (CDIF102978_01561) pnp 1547636..1549747 (+) 2112 WP_003438316.1 polyribonucleotide nucleotidyltransferase -
  CDIF102978_RS07860 (CDIF102978_01562) - 1550013..1550756 (+) 744 WP_065977572.1 polysaccharide deacetylase family protein -
  CDIF102978_RS07865 (CDIF102978_01563) - 1550914..1552161 (+) 1248 WP_021375063.1 M16 family metallopeptidase -
  CDIF102978_RS07870 (CDIF102978_01564) - 1552196..1552441 (+) 246 WP_003419503.1 YlmC/YmxH family sporulation protein -
  CDIF102978_RS07875 (CDIF102978_01565) dapG 1552451..1553674 (+) 1224 WP_003438324.1 aspartate kinase -
  CDIF102978_RS07880 (CDIF102978_01566) - 1553787..1554521 (+) 735 WP_003428224.1 ClpP family protease -
  CDIF102978_RS07885 (CDIF102978_01567) - 1554644..1557055 (+) 2412 WP_021375068.1 FtsK/SpoIIIE family DNA translocase -
  CDIF102978_RS07890 (CDIF102978_01568) mnmH 1557058..1558116 (+) 1059 WP_021375070.1 tRNA 2-selenouridine(34) synthase MnmH -
  CDIF102978_RS07895 (CDIF102978_01569) rimO 1558110..1559444 (+) 1335 WP_065977573.1 30S ribosomal protein S12 methylthiotransferase RimO -
  CDIF102978_RS07900 (CDIF102978_01570) pgsA 1559431..1559973 (+) 543 WP_009889106.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  CDIF102978_RS07905 (CDIF102978_01571) recA 1560261..1561307 (+) 1047 WP_021375046.1 recombinase RecA Machinery gene
  CDIF102978_RS07910 (CDIF102978_01572) rny 1561483..1563024 (+) 1542 WP_003428216.1 ribonuclease Y -
  CDIF102978_RS07915 (CDIF102978_01573) - 1563659..1565440 (+) 1782 WP_021375060.1 UvrD-helicase domain-containing protein -
  CDIF102978_RS07920 (CDIF102978_01574) lepB 1565522..1566052 (-) 531 WP_021387803.1 signal peptidase I -
  CDIF102978_RS07925 (CDIF102978_01575) - 1566092..1566916 (-) 825 WP_074115256.1 undecaprenyl-diphosphate phosphatase -
  CDIF102978_RS07930 (CDIF102978_01576) - 1567173..1568081 (+) 909 WP_021375077.1 tyrosine-type recombinase/integrase -
  CDIF102978_RS07935 (CDIF102978_01577) purB 1568225..1569670 (+) 1446 WP_009889111.1 adenylosuccinate lyase -
  CDIF102978_RS07940 (CDIF102978_01578) - 1569981..1570433 (+) 453 WP_003428210.1 MarR family winged helix-turn-helix transcriptional regulator -
  CDIF102978_RS07945 (CDIF102978_01579) - 1570757..1571953 (-) 1197 WP_003438357.1 pyridoxal phosphate-dependent aminotransferase -
  CDIF102978_RS07950 (CDIF102978_01580) galT 1572338..1573288 (+) 951 WP_003428205.1 galactose-1-phosphate uridylyltransferase -
  CDIF102978_RS07955 (CDIF102978_01581) - 1573444..1574196 (+) 753 WP_021375058.1 exodeoxyribonuclease III -
  CDIF102978_RS07960 (CDIF102978_01582) - 1574288..1575064 (-) 777 WP_009896237.1 3'-5' exonuclease -
  CDIF102978_RS07965 (CDIF102978_01583) - 1575378..1577276 (+) 1899 WP_021375065.1 glutamine synthetase catalytic domain protein -
  CDIF102978_RS07970 (CDIF102978_01584) - 1577404..1578525 (-) 1122 WP_074115261.1 MGDG synthase family glycosyltransferase -
  CDIF102978_RS07975 (CDIF102978_01585) - 1578724..1579056 (+) 333 WP_009889116.1 PadR family transcriptional regulator -
  CDIF102978_RS07980 (CDIF102978_01586) - 1579043..1580101 (+) 1059 WP_032547310.1 DUF1700 domain-containing protein -
  CDIF102978_RS07985 (CDIF102978_01587) - 1580094..1581164 (+) 1071 WP_021375061.1 DUF4097 family beta strand repeat-containing protein -
  CDIF102978_RS07990 (CDIF102978_01588) - 1581266..1581802 (+) 537 WP_021375052.1 lipoprotein -
  CDIF102978_RS07995 (CDIF102978_01589) - 1581918..1582625 (+) 708 WP_021375085.1 lantibiotic protection ABC transporter ATP-binding protein -
  CDIF102978_RS08000 (CDIF102978_01590) - 1582627..1583343 (+) 717 WP_021375064.1 lantibiotic immunity ABC transporter MutE/EpiE family permease subunit -
  CDIF102978_RS08005 (CDIF102978_01591) - 1583345..1584103 (+) 759 WP_045145715.1 lantibiotic immunity ABC transporter MutG family permease subunit -
  CDIF102978_RS08010 (CDIF102978_01592) - 1584238..1585626 (+) 1389 WP_021375047.1 two-component system sensor histidine kinase -
  CDIF102978_RS08015 (CDIF102978_01593) - 1585702..1586523 (-) 822 WP_003428191.1 pyridoxamine kinase -
  CDIF102978_RS08020 (CDIF102978_01594) - 1586774..1587928 (+) 1155 WP_009902426.1 amidase domain-containing protein -
  CDIF102978_RS08025 (CDIF102978_01595) - 1588111..1588311 (+) 201 WP_003419624.1 cold-shock protein -
  CDIF102978_RS08030 (CDIF102978_01596) - 1588732..1589160 (+) 429 WP_009889129.1 CBS domain-containing protein -
  CDIF102978_RS08035 (CDIF102978_01597) - 1589303..1590058 (-) 756 WP_009889131.1 peptidylprolyl isomerase -
  CDIF102978_RS08045 (CDIF102978_01599) - 1590759..1591265 (-) 507 WP_003428186.1 ImmA/IrrE family metallo-endopeptidase -
  CDIF102978_RS08050 (CDIF102978_01600) - 1591347..1591667 (-) 321 WP_021375083.1 XRE family transcriptional regulator -
  CDIF102978_RS08055 (CDIF102978_01601) - 1591836..1592057 (+) 222 WP_021375081.1 helix-turn-helix transcriptional regulator -
  CDIF102978_RS08060 (CDIF102978_01602) - 1592136..1592576 (+) 441 WP_009889133.1 hypothetical protein -
  CDIF102978_RS08065 (CDIF102978_01603) - 1592825..1593268 (+) 444 WP_021375062.1 phage tail terminator family protein -
  CDIF102978_RS08070 (CDIF102978_01604) - 1593273..1594337 (+) 1065 WP_021375078.1 phage tail sheath subtilisin-like domain-containing protein -
  CDIF102978_RS08075 (CDIF102978_01605) - 1594351..1594779 (+) 429 WP_021375066.1 phage tail tube protein -
  CDIF102978_RS08080 (CDIF102978_01606) - 1594893..1595339 (+) 447 WP_021366507.1 phage tail assembly chaperone -
  CDIF102978_RS08085 (CDIF102978_01607) - 1595366..1595533 (+) 168 WP_003419648.1 hypothetical protein -
  CDIF102978_RS08090 (CDIF102978_01608) - 1595533..1597932 (+) 2400 WP_077708755.1 hypothetical protein -
  CDIF102978_RS08095 (CDIF102978_01609) - 1597938..1598354 (+) 417 WP_021375053.1 phage baseplate protein -
  CDIF102978_RS08100 (CDIF102978_01610) - 1598540..1600165 (+) 1626 WP_418657942.1 XkdQ/YqbQ family protein -
  CDIF102978_RS08105 (CDIF102978_01611) - 1600181..1600507 (+) 327 WP_021375074.1 DUF2577 domain-containing protein -
  CDIF102978_RS08110 (CDIF102978_01612) - 1600507..1600935 (+) 429 WP_003428161.1 DUF2634 domain-containing protein -
  CDIF102978_RS08115 (CDIF102978_01613) - 1600928..1601980 (+) 1053 WP_065986623.1 baseplate J/gp47 family protein -
  CDIF102978_RS08120 (CDIF102978_01614) - 1601977..1602675 (+) 699 WP_003428156.1 putative phage tail protein -
  CDIF102978_RS08125 (CDIF102978_01615) - 1602676..1603662 (+) 987 WP_021375149.1 phage tail protein -

Sequence


Protein


Download         Length: 348 a.a.        Molecular weight: 37376.66 Da        Isoelectric Point: 4.8236

>NTDB_id=221982 CDIF102978_RS07905 WP_021375046.1 1560261..1561307(+) (recA) [Clostridioides difficile strain DSM 102978]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTNEI
DEKVRAFYNLNEEHEESGTSVSKEVVEE

Nucleotide


Download         Length: 1047 bp        

>NTDB_id=221982 CDIF102978_RS07905 WP_021375046.1 1560261..1561307(+) (recA) [Clostridioides difficile strain DSM 102978]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAGACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCAGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGACACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGGATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAGTCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAGGATAATTTAGATTTAACGAATGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTACTTCAGTATCAAAAGAAGTTGTAGA
AGAATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recA Streptococcus mutans UA159

66.762

100

0.67

  recA Streptococcus mitis SK321

66.185

99.425

0.658

  recA Streptococcus pneumoniae D39

65.507

99.138

0.649

  recA Streptococcus pneumoniae TIGR4

65.507

99.138

0.649

  recA Streptococcus pneumoniae R6

65.507

99.138

0.649

  recA Streptococcus pneumoniae Rx1

65.507

99.138

0.649

  recA Streptococcus mitis NCTC 12261

68.085

94.54

0.644

  recA Bacillus subtilis subsp. subtilis str. 168

69.565

92.529

0.644

  recA Lactococcus lactis subsp. cremoris KW2

65.569

95.977

0.629

  recA Streptococcus pyogenes NZ131

66.972

93.966

0.629

  recA Riemerella anatipestifer ATCC 11845 = DSM 15868

65.758

94.828

0.624

  recA Latilactobacillus sakei subsp. sakei 23K

64.955

95.115

0.618

  recA Neisseria gonorrhoeae MS11

66.049

93.103

0.615

  recA Neisseria gonorrhoeae MS11

66.049

93.103

0.615

  recA Neisseria gonorrhoeae strain FA1090

66.049

93.103

0.615

  recA Acinetobacter baylyi ADP1

64.087

92.816

0.595

  recA Pseudomonas stutzeri DSM 10701

63.889

93.103

0.595

  recA Helicobacter pylori 26695

61.976

95.977

0.595

  recA Helicobacter pylori strain NCTC11637

61.976

95.977

0.595

  recA Acinetobacter baumannii D1279779

63.777

92.816

0.592

  recA Vibrio cholerae O1 biovar El Tor strain E7946

62.048

95.402

0.592

  recA Vibrio cholerae strain A1552

62.048

95.402

0.592

  recA Glaesserella parasuis strain SC1401

64.174

92.241

0.592

  recA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

63.272

93.103

0.589

  recA Ralstonia pseudosolanacearum GMI1000

66.558

88.506

0.589

  recA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

60.681

92.816

0.563


Multiple sequence alignment