Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   B6R96_RS16930 Genome accession   NZ_CP020555
Coordinates   3823142..3823813 (+) Length   223 a.a.
NCBI ID   WP_030383691.1    Uniprot ID   A0A0L8N5J7
Organism   Streptomyces sp. Sge12     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3818142..3828813
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B6R96_RS16905 (B6R96_16905) - 3818541..3818930 (+) 390 WP_081522850.1 nuclear transport factor 2 family protein -
  B6R96_RS16910 (B6R96_16910) - 3818984..3819286 (-) 303 WP_203351632.1 hypothetical protein -
  B6R96_RS16915 (B6R96_16915) - 3819574..3820542 (+) 969 WP_203351633.1 alpha/beta hydrolase -
  B6R96_RS16920 (B6R96_16920) - 3820535..3821806 (+) 1272 WP_237291442.1 acyltransferase -
  B6R96_RS16925 (B6R96_16925) - 3821829..3823145 (+) 1317 WP_237291443.1 sensor histidine kinase -
  B6R96_RS16930 (B6R96_16930) vraR 3823142..3823813 (+) 672 WP_030383691.1 response regulator transcription factor Regulator
  B6R96_RS16935 (B6R96_16935) - 3823902..3825239 (+) 1338 WP_081522854.1 histidine kinase -
  B6R96_RS16940 (B6R96_16940) vraR 3825236..3825895 (+) 660 WP_030383693.1 response regulator transcription factor Regulator
  B6R96_RS16945 (B6R96_16945) - 3825925..3827133 (+) 1209 WP_081522855.1 cytochrome P450 -
  B6R96_RS16950 (B6R96_16950) - 3827172..3828773 (-) 1602 WP_081522856.1 ABC transporter permease -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 23812.54 Da        Isoelectric Point: 4.6064

>NTDB_id=187604 B6R96_RS16930 WP_030383691.1 3823142..3823813(+) (vraR) [Streptomyces sp. Sge12]
MSTPIKVMIADDQMMVRQGFTVLLNAQPDIEVVGQAVDGADAVAKVAELAPDVVLMDIRMPGMGGIEATSVITAVPDAAV
KVLVLTTFDLDEYVYEALRAGASGFLLKDASADQLAEAVRVVAAGEALLSPNITKRLITEFSRLGAPRAPSRARIEALTE
RETEVLSLIAQGLSNAEISEHLVLAEQTVKTHVSRILVKLGLRDRTQAAVFAYETGLIRPTGY

Nucleotide


Download         Length: 672 bp        

>NTDB_id=187604 B6R96_RS16930 WP_030383691.1 3823142..3823813(+) (vraR) [Streptomyces sp. Sge12]
ATGAGCACCCCGATCAAGGTGATGATCGCCGACGACCAGATGATGGTCCGGCAGGGCTTCACCGTGCTTCTCAACGCGCA
GCCAGACATAGAGGTCGTGGGGCAGGCGGTGGACGGGGCGGACGCGGTGGCGAAGGTCGCCGAGCTGGCCCCGGACGTGG
TGCTGATGGACATCCGTATGCCGGGGATGGGCGGGATCGAGGCCACGTCCGTCATCACCGCGGTGCCGGACGCCGCCGTG
AAGGTGCTGGTGCTGACGACCTTCGATCTCGACGAGTACGTGTACGAGGCGCTGCGCGCCGGGGCCTCCGGGTTCCTGCT
CAAGGACGCGTCGGCCGACCAGCTCGCCGAGGCGGTGCGGGTGGTGGCGGCCGGCGAGGCTCTGCTGTCGCCGAACATCA
CGAAGCGGCTGATCACGGAGTTCTCCCGGCTGGGGGCGCCGCGCGCGCCGTCGCGGGCCCGGATCGAGGCGCTGACCGAG
CGGGAGACCGAGGTGCTGTCGCTGATCGCCCAGGGCCTGTCGAATGCCGAGATCTCGGAGCACCTGGTGCTGGCCGAGCA
GACGGTGAAGACGCATGTGAGCCGGATCCTGGTGAAGCTCGGCCTGCGGGACCGCACGCAGGCGGCCGTGTTCGCGTACG
AGACCGGTCTGATCCGCCCGACGGGCTACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-120)

Bacterial regulatory proteins, luxR family (GerE)

(157-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0L8N5J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.161

97.309

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

42.291

100

0.43

Multiple sequence alignment