Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   U069_RS18925 Genome accession   NZ_CP011343
Coordinates   3830099..3830689 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli K-12 substr. GM4792     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3825099..3835689
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U069_RS18910 (U069_c0066) uhpT 3825739..3827130 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  U069_RS18915 (U069_c0067) uhpC 3827268..3828587 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  U069_RS18920 (U069_c0068) uhpB 3828597..3830099 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  U069_RS18925 (U069_c0069) letA 3830099..3830689 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  U069_RS18930 (U069_c0070) ilvN 3830765..3831055 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  U069_RS18935 (U069_c0071) ilvB 3831059..3832747 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  U069_RS18940 ivbL 3832853..3832951 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  U069_RS18955 (U069_c4044) tisB 3833516..3833605 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  U069_RS25960 ysdE 3833729..3833803 (-) 75 WP_211180519.1 protein YsdE -
  U069_RS18960 (U069_c0072) emrD 3833885..3835069 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  U069_RS18965 (U069_c0073) yidF 3835077..3835574 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=127783 U069_RS18925 WP_000633668.1 3830099..3830689(-) (letA) [Escherichia coli K-12 substr. GM4792]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=127783 U069_RS18925 WP_000633668.1 3830099..3830689(-) (letA) [Escherichia coli K-12 substr. GM4792]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment