Detailed information    

insolico Bioinformatically predicted

Overview

Name   recA   Type   Machinery gene
Locus tag   EW024_RS08855 Genome accession   NZ_LR130237
Coordinates   1748460..1749596 (-) Length   378 a.a.
NCBI ID   WP_002992179.1    Uniprot ID   A0A4Q1QZP2
Organism   Streptococcus pyogenes strain SP444 isolate SP444     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1743460..1754596
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW024_RS08830 - 1744682..1746241 (-) 1560 WP_011055088.1 membrane protein -
  EW024_RS08835 - 1746655..1746960 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  EW024_RS08840 ruvX 1746972..1747391 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  EW024_RS08845 - 1747388..1747657 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  EW024_RS08850 spx 1747771..1748169 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  EW024_RS08855 recA 1748460..1749596 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  EW024_RS08860 cinA 1749685..1750956 (-) 1272 WP_002992182.1 competence/damage-inducible protein A Machinery gene
  EW024_RS08865 - 1751025..1751585 (-) 561 WP_002992183.1 DNA-3-methyladenine glycosylase I -
  EW024_RS08870 ruvA 1751595..1752191 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA -
  EW024_RS08875 - 1752193..1753413 (-) 1221 WP_011529098.1 MDR family MFS transporter -

Sequence

Protein


Download         Length: 378 a.a.        Molecular weight: 40631.23 Da        Isoelectric Point: 4.9004

>NTDB_id=1116587 EW024_RS08855 WP_002992179.1 1748460..1749596(-) (recA) [Streptococcus pyogenes strain SP444 isolate SP444]
MAKKLKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGP
ESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYASVRLDVRG
TTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAEVEIMYGEGISRTGELVKIASDLDIIQKAGAWFSYNGEKIGQGSE
NAKRYLADHPQLFDEIDRKVRVKFGLLEESEEESAMAVASEETDDLALDLDNGIEIED

Nucleotide


Download         Length: 1137 bp        

>NTDB_id=1116587 EW024_RS08855 WP_002992179.1 1748460..1749596(-) (recA) [Streptococcus pyogenes strain SP444 isolate SP444]
TTGGCAAAAAAATTAAAAAAGAATGAAGAAATCACTAAGAAGTTTGGTGACGAACGTCGCAAAGCTCTTGATGATGCTTT
GAAAAATATTGAAAAAGATTTCGGTAAGGGCGCAGTGATGCGATTAGGAGAACGTGCAGAGCAAAAAGTTCAGGTTATGA
GTTCAGGAAGTCTAGCTCTTGATATTGCGCTTGGAGCTGGTGGTTATCCTAAAGGACGTATCATCGAAATCTATGGTCCA
GAGTCTTCCGGTAAAACGACTGTGGCTTTACATGCTGTAGCACAAGCTCAAAAAGAAGGTGGAATCGCAGCCTTTATCGA
TGCCGAGCATGCGCTTGATCCAGCTTATGCTGCTGCGCTTGGGGTTAATATTGATGAACTCCTCTTGTCTCAACCAGATT
CTGGAGAACAAGGACTTGAAATTGCAGGTAAATTGATTGATTCTGGTGCGGTTGATCTGGTTGTTGTCGATTCAGTAGCA
GCTTTAGTGCCACGTGCTGAAATTGATGGTGATATTGGCGATAGCCATGTCGGATTGCAAGCACGTATGATGAGTCAGGC
CATGCGTAAATTATCAGCTTCTATTAATAAAACAAAAACTATCGCTATTTTTATTAACCAATTGCGTGAAAAAGTTGGTG
TGATGTTTGGAAATCCTGAAACAACACCAGGTGGTCGAGCTTTGAAATTCTATGCTTCTGTTCGGCTGGATGTGCGTGGA
ACAACTCAAATTAAAGGAACTGGTGACCAAAAGGATAGCAGCATTGGTAAGGAGACCAAAATCAAGGTTGTTAAAAACAA
GGTCGCTCCGCCATTTAAGGTAGCAGAAGTTGAAATCATGTATGGGGAAGGTATTTCTCGTACAGGGGAGCTTGTGAAAA
TTGCTTCTGATTTGGACATTATCCAAAAAGCAGGTGCTTGGTTCTCTTATAATGGTGAGAAGATTGGCCAAGGTTCTGAA
AATGCTAAGCGTTATTTGGCCGATCATCCACAATTGTTTGATGAAATCGACCGTAAAGTACGTGTTAAATTTGGTTTGCT
TGAAGAAAGCGAAGAAGAATCTGCTATGGCAGTAGCATCAGAAGAAACCGATGATCTTGCTTTAGATTTAGATAATGGTA
TTGAAATTGAAGATTAA

Domains

Predicted by InterproScan.

recA bacterial DNA recombination protein (RecA)

(21-286)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Q1QZP2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recA Streptococcus pyogenes NZ131

99.735

100

0.997
  recA Streptococcus mutans UA159

87.467

100

0.886
  recA Streptococcus mitis NCTC 12261

85.34

100

0.862
  recA Streptococcus pneumoniae Rx1

84.416

100

0.86
  recA Streptococcus pneumoniae D39

84.416

100

0.86
  recA Streptococcus pneumoniae R6

84.416

100

0.86
  recA Streptococcus pneumoniae TIGR4

84.416

100

0.86
  recA Streptococcus mitis SK321

85.302

100

0.86
  recA Lactococcus lactis subsp. cremoris KW2

78.754

93.386

0.735
  recA Latilactobacillus sakei subsp. sakei 23K

70.623

89.153

0.63
  recA Bacillus subtilis subsp. subtilis str. 168

68.085

87.037

0.593
  recA Acinetobacter baylyi ADP1

60

92.593

0.556
  recA Acinetobacter baumannii D1279779

59.49

93.386

0.556
  recA Riemerella anatipestifer ATCC 11845 = DSM 15868

62.018

89.153

0.553
  recA Neisseria gonorrhoeae MS11

60.058

90.741

0.545
  recA Neisseria gonorrhoeae MS11

60.058

90.741

0.545
  recA Neisseria gonorrhoeae strain FA1090

60.058

90.741

0.545
  recA Vibrio cholerae strain A1552

58.286

92.593

0.54
  recA Vibrio cholerae O1 biovar El Tor strain E7946

58.286

92.593

0.54
  recA Glaesserella parasuis strain SC1401

59.706

89.947

0.537
  recA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

62.539

85.45

0.534
  recA Pseudomonas stutzeri DSM 10701

56.897

92.063

0.524
  recA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.912

87.566

0.516
  recA Helicobacter pylori 26695

58.084

88.36

0.513
  recA Helicobacter pylori strain NCTC11637

58.084

88.36

0.513
  recA Ralstonia pseudosolanacearum GMI1000

57.831

87.831

0.508

Multiple sequence alignment