Detailed information NTG1010923

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: H1W90_RS03515
• Genome accession: NZ_LR822033
• Coordinates: 671331..673484 (-)
• Length: 717 a.a.
• NCBI ID: WP_039671034.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1048
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 666331..678484

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W90_RS09910 (STHERMO_0749)	-	666628..667023 (-)	396	WP_232085807.1	hypothetical protein	-
H1W90_RS03490 (STHERMO_0750)	-	667222..667563 (+)	342	WP_024404826.1	LytR/AlgR family response regulator transcription factor	-
H1W90_RS03495 (STHERMO_0751)	comE/blpR	667565..668305 (+)	741	WP_096811959.1	response regulator transcription factor	Regulator
H1W90_RS03500 (STHERMO_0752)	-	668316..669656 (+)	1341	WP_039671036.1	sensor histidine kinase	-
H1W90_RS03505 (STHERMO_0753)	-	669704..669859 (-)	156	WP_096811960.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
H1W90_RS03510 (STHERMO_0754)	comB	669958..671319 (-)	1362	WP_173940475.1	bacteriocin secretion accessory protein	Regulator
H1W90_RS03515 (STHERMO_0755)	comA/nlmT	671331..673484 (-)	2154	WP_039671034.1	peptide cleavage/export ABC transporter	Regulator
H1W90_RS03520 (STHERMO_0756)	-	673781..674035 (+)	255	WP_039671033.1	Blp family class II bacteriocin	-
H1W90_RS03525 (STHERMO_0757)	-	674050..674253 (+)	204	WP_039671032.1	Blp family class II bacteriocin	-
H1W90_RS03530 (STHERMO_0758)	-	674767..675045 (-)	279	Protein_657	transposase	-
H1W90_RS03535	-	675253..676357 (-)	1105	Protein_658	IS3 family transposase	-
H1W90_RS03540 (STHERMO_0761)	-	677048..677254 (+)	207	WP_065973044.1	Blp family class II bacteriocin	-
H1W90_RS03545 (STHERMO_0762)	-	677295..677483 (+)	189	WP_039671028.1	hypothetical protein	-
H1W90_RS03550 (STHERMO_0764)	-	678193..678450 (+)	258	WP_039671027.1	Blp family class II bacteriocin	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80525.36 Da
• Isoelectric Point: 7.1488

>NTDB_id=1010923 H1W90_RS03515 WP_039671034.1 671331..673484(-) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_1048]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDYSLAHLRELAKTNKEGTTALGIVKAAQEIGFETRAIQADMSLFDMNDV
PYPFIVHVNKEGKLQHYYVVYQTKKDHLIIGDPDPTVKVTKMSKERFSSEWTGVAIFLAPEPSYKPHKDKKNGLMSFLPL
IFRQRALIFYIVLASLLVTLINIGGSYYLQGILDEYIPNQMKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILTIVGGVLLVQNTNLFLLSLISVPIYII
IIFAFMKPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKSFKLSKYSILQTTLKQGAQL
ILNIVILWFGAQLVMNGHISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVESEFSNSQTLTDSQFL
TGDIRFEDLSYKYGFGRDTLSDINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYKGRITINNNDLKLIDKKTLRQHI
NYLPQQAYIFSGSILENLTLGANQLISQEDIIRACEIAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMAMADKTIIFVAHRLSISERTNQVIVLDQGKVIETGSHHELMTKQGFYHHLFSK

Nucleotide

• Length: 2154 bp

>NTDB_id=1010923 H1W90_RS03515 WP_039671034.1 671331..673484(-) (comA/nlmT) [Streptococcus thermophilus isolate STH_CIRM_1048]
ATGACCTCTTATAAACGAACCTTTGTTCCTCAAATTGATGCCAGAGACTGTGGTGTAGCTGCTTTAGCTTCTATTGCCAA
GTTTTACGGTTCTGACTATTCTCTAGCTCATTTGAGAGAATTAGCCAAAACTAACAAGGAAGGAACAACCGCACTTGGTA
TCGTTAAAGCTGCCCAAGAAATAGGCTTTGAGACAAGAGCCATCCAAGCTGATATGAGCCTTTTTGATATGAATGATGTC
CCTTACCCTTTCATCGTTCACGTCAATAAAGAAGGAAAGCTCCAACACTACTATGTAGTGTATCAAACCAAAAAAGATCA
TCTTATCATTGGTGATCCTGACCCTACAGTCAAGGTGACAAAGATGTCCAAGGAGCGATTTTCTTCTGAATGGACTGGTG
TAGCCATTTTTCTAGCTCCAGAGCCTAGCTACAAACCTCATAAGGATAAAAAGAACGGCCTGATGAGTTTTCTCCCTCTG
ATTTTCAGGCAACGTGCGCTTATCTTTTATATCGTCTTGGCTAGCCTTTTGGTGACGCTTATCAATATTGGTGGTTCTTA
CTACCTGCAAGGGATTTTGGATGAATACATTCCTAATCAAATGAAGTCAACCTTGGGGATTATCTCCATCGGCTTGATTA
TCACCTACATCCTCCAGCAGATGATGAGTTTCTCACGAGATTACCTTTTGACTGTGCTCAGCCAGCGGCTAAGTATTGAT
GTGATTCTTTCCTATATCCGTCATATCTTTGAACTGCCCATGTCCTTCTTTGCGACGCGGCGGACTGGTGAGGTTATCTC
TCGCTTTACAGATGCCAATTCAATCATTGATGCCCTGGCATCGACCATTTTGTCACTCTTCCTTGATGTCTCTATTTTGA
CCATCGTCGGTGGTGTGCTTTTGGTACAAAACACCAACCTCTTCCTGCTCTCCTTGATTTCAGTTCCCATTTACATCATC
ATTATTTTTGCTTTTATGAAGCCGTTTGAGAAGATGAATAACGATGTTATGCAGAGCAATTCCATGGTCAGCTCTGCCAT
TATCGAAGACATCAACGGCATTGAAACCATCAAATCCTTGACCAGCGAAGAAAGCCGCTACCAGAAGATTGATAGCGAGT
TCGTAGATTACCTGGACAAATCCTTCAAACTCAGTAAATACTCTATCCTGCAAACTACCCTTAAACAGGGAGCTCAGCTC
ATTCTAAATATCGTCATCTTGTGGTTTGGGGCTCAACTAGTCATGAACGGACACATTTCAGTTGGACAACTGATCACCTT
CAACACCCTTCTATCTTATTTTACCAATCCTTTAGAAAATATTATAAACCTCCAAACCAAGCTCCAGTCTGCCAAGGTGG
CTAACAATCGCCTGAATGAAGTCTACCTGGTTGAATCTGAATTCAGTAACAGTCAGACCTTAACAGATTCACAGTTCCTG
ACTGGCGATATTCGCTTTGAAGACCTTTCCTATAAGTACGGTTTCGGACGTGACACCCTATCGGATATCAATCTGACCAT
CAAACAAGGCGATAAGGTCAGTCTAGTGGGAATTAGCGGCTCAGGAAAGACAACCTTGGCCAAGATGATTGTCAATTTCT
TTGAGCCTTACAAGGGTCGAATCACCATCAACAACAATGACCTTAAACTAATTGATAAAAAGACGCTTCGGCAACACATT
AACTACCTCCCACAACAAGCTTATATCTTCAGTGGTTCAATCTTAGAAAACTTGACTTTAGGGGCTAATCAACTGATTAG
TCAGGAAGATATTATCAGAGCTTGTGAGATCGCTGAAATTCGACAAGATATCGAGCAGATGCCTATGGGCTATCAAACAG
AATTGTCTGACGGAGCTGGCTTATCGGGTGGTCAAAAGCAACGGATTGCTTTGGCTAGGGCTCTACTGACTAAAGCCCCT
GTTCTTATTCTTGATGAAGCCACTAGCGGCCTTGATGTGCTAACGGAGAAAAAGGTCATTGATAATTTAATGGCCATGGC
AGACAAGACCATTATCTTTGTCGCACACCGCCTCAGTATTTCTGAGCGAACCAACCAAGTTATCGTTCTTGACCAAGGGA
AGGTCATTGAGACTGGTTCACATCACGAATTGATGACCAAACAAGGTTTCTACCATCATCTATTTAGCAAGTAA

Domains

Predicted by InterProScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

• ABC transporter transmembrane region (ABC_membrane) (168-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	74.126	99.721	0.739
comA	Streptococcus mitis NCTC 12261	68.495	99.163	0.679
comA	Streptococcus pneumoniae Rx1	67.932	99.163	0.674
comA	Streptococcus pneumoniae D39	67.932	99.163	0.674
comA	Streptococcus pneumoniae R6	67.932	99.163	0.674
comA	Streptococcus mitis SK321	67.932	99.163	0.674
comA	Streptococcus pneumoniae TIGR4	67.651	99.163	0.671
comA	Streptococcus gordonii str. Challis substr. CH1	65.874	99.721	0.657