Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01240  |
| T6SS type | Type i5 |
| Strain | Agrobacterium fabrum strain 1D132 |
| Replicon (RefSeq) | chromosome (NZ_CP033023) |
| Location | 1429744..1454431 |
| Function | anti-bacterial |
| Comment | T6SS exhibits antibacterial and secrete hcp activity |
| References | [1] Wu CF, Santos MNM, Cho ST, Chang HH, Tsai YM, Smith DA, Kuo CH, Chang JH, Lai EM. et al (2019) Plant-Pathogenic Agrobacterium tumefaciens Strains Have Diverse Type VI Effector-Immunity Pairs and Vary in In-Planta Competitiveness.. Mol Plant Microbe Interact. 32(8):961-971. [PudMed:30830835] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | Tae4 | TagF | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| At1D132_RS21295 (proP) | 1425460..1426980 | - | 1521 | WP_162992447.1 | glycine betaine/L-proline transporter ProP | ||
| At1D132_RS21300 | 1427146..1427442 | - | 297 | WP_006315910.1 | PRC-barrel domain-containing protein | ||
| At1D132_RS21305 | 1427707..1428843 | + | 1137 | WP_092772441.1 | polysaccharide export protein | ||
| At1D132_RS21310 | 1428852..1429757 | - | 906 | WP_162992448.1 | protein kinase | ||
| T6CP015538 | TagF | At1D132_RS21315 (tagF) | 1429744..1431159 | - | 1416 | WP_092772439.1 | type VI secretion system-associated protein TagF |
| T6CP015539 | TssM | At1D132_RS21320 (tssM) | 1431242..1434721 | - | 3480 | WP_092772437.1 | type VI secretion system membrane subunit TssM |
| T6CP015540 | TssL | At1D132_RS21325 (tssL) | 1434718..1436223 | - | 1506 | WP_092772435.1 | type VI secretion system protein TssL, long form |
| T6CP015541 | TssK | At1D132_RS21330 (tssK) | 1436220..1437560 | - | 1341 | WP_092772433.1 | type VI secretion system baseplate subunit TssK |
| At1D132_RS21335 | 1437550..1438749 | - | 1200 | WP_010973758.1 | type VI secretion system-associated FHA domain protein | ||
| T6CP015542 | TssG | At1D132_RS21340 (tssG) | 1438760..1439764 | - | 1005 | WP_010973759.1 | type VI secretion system baseplate subunit TssG |
| T6CP015543 | TssF | At1D132_RS21345 (tssF) | 1439774..1441555 | - | 1782 | WP_010973760.1 | type VI secretion system baseplate subunit TssF |
| T6CP015544 | TssE | At1D132_RS21350 (tssE) | 1441548..1442057 | - | 510 | WP_006315898.1 | type VI secretion system baseplate subunit TssE |
| At1D132_RS21355 | 1442050..1442874 | - | 825 | WP_092772431.1 | nitrogen fixation protein | ||
| T6CP015545 | TssC | At1D132_RS21360 (tssC) | 1442871..1444265 | - | 1395 | WP_006315896.1 | type VI secretion system contractile sheath large subunit |
| T6CP015546 | TssC | At1D132_RS21365 (tssC) | 1444320..1445801 | - | 1482 | WP_006315895.1 | type VI secretion system contractile sheath large subunit |
| T6CP015547 | TssB | At1D132_RS21370 (tssB) | 1445895..1446404 | - | 510 | WP_010973761.1 | type VI secretion system contractile sheath small subunit |
| T6CP015548 | TssA | At1D132_RS21375 (tssA) | 1446470..1447525 | - | 1056 | WP_092772429.1 | type VI secretion system protein TssA |
| T6CP015549 | TssH | At1D132_RS21380 (tssH) | 1447746..1450424 | + | 2679 | WP_092733927.1 | type VI secretion system ATPase TssH |
| T6CP015550 | TssD | At1D132_RS21385 | 1450482..1450958 | + | 477 | WP_003504561.1 | type VI secretion system tube protein Hcp |
| At1D132_RS21390 | 1451065..1451454 | + | 390 | WP_010973764.1 | hypothetical protein | ||
| T6CP015551 | Tae4 | At1D132_RS21395 | 1451466..1451966 | + | 501 | WP_006315890.1 | type VI secretion system amidase effector protein Tae4 |
| T6CP015552 | TssI | At1D132_RS21400 (tssI) | 1451981..1454431 | + | 2451 | WP_121651778.1 | type VI secretion system tip protein VgrG |
| At1D132_RS21405 | 1454434..1455390 | + | 957 | WP_010973766.1 | DUF4123 domain-containing protein | ||
| At1D132_RS21410 | 1455387..1456223 | + | 837 | WP_010973767.1 | hypothetical protein | ||
| At1D132_RS21415 | 1456251..1456925 | + | 675 | WP_010973768.1 | DUF1851 domain-containing protein | ||
| At1D132_RS21420 | 1456938..1457243 | + | 306 | WP_010973769.1 | PAAR domain-containing protein | ||
| At1D132_RS21425 | 1457382..1459328 | - | 1947 | WP_035257634.1 | bifunctional diguanylate cyclase/phosphodiesterase |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF01852 |
At1D132_RS21395 (Tae4) | Tae | Agrobacterium fabrum strain 1D132 | chromosome (NZ_CP033023) | 1451466..1451966 (+) | 493359403 | |
| EFF01853 |
At1D132_RS21410 (Tde1) | Tde | - | Agrobacterium fabrum strain 1D132 | chromosome (NZ_CP033023) | 1455387..1456223 (+) | 499280706 |
| EFF01851 |
At1D132_RS21385 (Hcp) | - | - | Agrobacterium fabrum strain 1D132 | chromosome (NZ_CP033023) | 1450482..1450958 (+) | 489600119 |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|