Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS00382 experimental
T6SS type Type i3
Strain Xenorhabdus bovienii SS-2004
Replicon (RefSeq) chromosome (NC_013892)
Location 2053604..2079234
Function anti-bacterial
Comment The hcp1 mutant was unable to kill the prey on solid media, and this defect can be complemented by introducing hcp1 on a plasmid. T6SS-1 and T6SS-2 facilitated biofilm formation in XBJ.
References
[1] Kochanowsky RM, Bradshaw C, Forlastro I, Stock SP. et al (2020) Xenorhabdus bovienii strain jolietti uses a type 6 secretion system to kill closely related Xenorhabdus strains.. FEMS Microbiol Ecol. 96(8). [PudMed:32558899]
experimental Experimental investigation has been performed.

T6SS components and genome coordinates

ComponentFHATssATssBTssCTssDTssETssFTssGTssHTssITssJTssKTssLTssM
Number11111111111111


Component ID Component Locus tag (Gene) Coordinate Strand Size (bp) NCBI ID Product
XBJ1_RS08870 2048626..2049093 + 468 WP_143827653.1 hypothetical protein
XBJ1_RS08875 2049240..2049680 + 441 WP_012988541.1 GNAT family N-acetyltransferase
XBJ1_RS08880 2049932..2050144 - 213 WP_012988543.1 hypothetical protein
XBJ1_RS20755 2050346..2051040 - 695 WP_143827612.1 IS1 family transposase
XBJ1_RS08890 2051099..2051299 - 201 pseudogene photopexin B
XBJ1_RS19795 2051533..2051783 + 251 pseudogene helix-turn-helix domain-containing protein
XBJ1_RS08900 2051865..2052560 + 696 WP_012988546.1 IS6 family transposase
XBJ1_RS08905 2052635..2053363 - 729 WP_012988547.1 hypothetical protein
T6CP003911 TssH XBJ1_RS08910 (tssH) 2053604..2056237 - 2634 WP_012988548.1 type VI secretion system ATPase TssH
T6CP003912 TssG XBJ1_RS08915 (tssG) 2056281..2057357 - 1077 WP_012988549.1 type VI secretion system baseplate subunit TssG
T6CP003913 TssF XBJ1_RS08920 (tssF) 2057415..2059289 - 1875 WP_012988550.1 type VI secretion system baseplate subunit TssF
T6CP003914 TssE XBJ1_RS08925 2059309..2059863 - 555 WP_012988551.1 GPW/gp25 family protein
T6CP011809 FHA XBJ1_RS08930 (tagH) 2059923..2061479 - 1557 WP_038198787.1 type VI secretion system-associated FHA domain protein TagH
T6CP009381 TssD XBJ1_RS08935 2061568..2062071 - 504 WP_012988553.1 type VI secretion system tube protein Hcp
T6CP003915 TssC XBJ1_RS08940 (tssC) 2062237..2063739 - 1503 WP_012988554.1 type VI secretion system contractile sheath large subunit
T6CP003916 TssB XBJ1_RS08945 (tssB) 2063743..2064294 - 552 WP_012988555.1 type VI secretion system contractile sheath small subunit
T6CP003917 TssA XBJ1_RS08950 (tssA) 2064485..2065540 - 1056 WP_012988556.1 type VI secretion system protein TssA
T6CP003918 TssM XBJ1_RS08955 (tssM) 2065703..2069218 - 3516 WP_012988557.1 type VI secretion system membrane subunit TssM
T6CP003919 TssL XBJ1_RS08960 2069231..2070442 - 1212 WP_012988558.1 DotU family type VI secretion system protein
T6CP003920 TssK XBJ1_RS08965 (tssK) 2070486..2071829 - 1344 WP_012988559.1 type VI secretion system baseplate subunit TssK
T6CP003921 TssJ XBJ1_RS08970 (tssJ) 2071856..2072368 - 513 WP_143827727.1 type VI secretion system lipoprotein TssJ
XBJ1_RS08975 2072520..2072921 - 402 WP_012988562.1 DUF4150 domain-containing protein
XBJ1_RS08980 2072942..2073604 - 663 WP_012988563.1 DUF3540 domain-containing protein
XBJ1_RS08985 2073619..2074692 - 1074 WP_012988564.1 pentapeptide repeat-containing protein
XBJ1_RS08990 2074689..2077283 - 2595 WP_012988565.1 DUF2169 domain-containing protein
T6CP003922 TssI XBJ1_RS08995 (tssI) 2077318..2079174 - 1857 WP_158304286.1 type VI secretion system tip protein VgrG
XBJ1_RS22010 2080030..2080165 - 136 pseudogene IS5/IS1182 family transposase
XBJ1_RS09000 2080593..2081126 + 534 WP_038198792.1 hypothetical protein
XBJ1_RS09005 2081723..2082508 + 786 WP_143827654.1 thioesterase II family protein
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Regulator ID Locus tag (Gene) Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Effector ID Locus tag (Gene) Classification Cognate immunity protein Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Immunity protein ID Locus tag (Gene) Cognate effector Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
Accessory protein ID Locus tag (Gene) Type             Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Related structure protein Related effector