Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00312  |
| T6SS type | Type i4b |
| Strain | Acinetobacter baumannii AB307-0294 |
| Replicon (RefSeq) | chromosome (NC_011595) |
| Location | 2367193..2386603 |
| Function | anti-bacterial |
| Comment | T6SS is functional in the mammalian gut and necessary for antagonism and protection. |
| References | [1] Chatzidaki-Livanis M, Geva-Zatorsky N, Comstock LE et al (2016) Bacteroides fragilis type VI secretion systems use novel effector and immunity proteins to antagonize human gut Bacteroidales species. Proc Natl Acad Sci U S A. 113(13):3627-32. [PudMed:26951680] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | PAAR | TagL | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
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Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| ABBFA_RS10960 | 2362265..2363443 | - | 1179 | 446736569 | cyanate transporter | ||
| ABBFA_RS10965 | 2363443..2363925 | - | 483 | 446569388 | nucleoside deaminase | ||
| ABBFA_RS10970 | 2363941..2364609 | - | 669 | 447154947 | ankyrin repeat domain-containing protein | ||
| ABBFA_RS10975 | 2364761..2365612 | + | 852 | 446382337 | LysR family transcriptional regulator | ||
| ABBFA_RS10980 | 2365615..2366569 | - | 955 | pseudogene | D-alanyl-D-alanine carboxypeptidase | ||
| ABBFA_RS10985 | 2366577..2366972 | - | 396 | 489206030 | hypothetical protein | ||
| T6CP003155 | TssL | ABBFA_RS10990 | 2367193..2367999 | - | 807 | 446005774 | type IVB secretion system protein IcmH/DotU |
| T6CP003156 | TssK | ABBFA_RS10995 | 2368017..2369381 | - | 1365 | 446393589 | type VI secretion system baseplate subunit TssK |
| T6CP003157 | TssA | ABBFA_RS11000 | 2369398..2370492 | - | 1095 | 445942858 | type VI secretion system protein TssA |
| T6CP003158 | TssH | ABBFA_RS11005 | 2370516..2373194 | - | 2679 | 446018690 | type VI secretion system ATPase TssH |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.
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Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF01486 | ABBFA_RS00580 | Tae/Tge | IMU00307 | Acinetobacter baumannii AB307-0294 | chromosome (NC_011595) | 131981..133729 (+) | 215481876 |
| EFF01484 | ABBFA_RS12570 | Tde | IMU00305 | Acinetobacter baumannii AB307-0294 | chromosome (NZ_CP001172) | 2670335..2671042 (-) | 446842107 |
| EFF01485 | ABBFA_RS11575 | Tde | IMU00306 | Acinetobacter baumannii AB307-0294 | chromosome (NZ_CP001172) | 2459651..2461072 (+) | 447105016 |
Showing 1 to 3 of 3 rows
Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| IMU00305 | ABBFA_02467 (Rhs1I) | EFF01484 | Acinetobacter baumannii AB307-0294 | chromosome (NZ_CP001172) | 2669468..2670331 (-) | 446971646 |
| IMU00306 | ABBFA_02274 (Rhs2I) | EFF01485 | Acinetobacter baumannii AB307-0294 | chromosome (NZ_CP001172) | 2458460..2459437 (-) | 447056300 |
| IMU00307 | ABBFA_00118 (LysMI) | EFF01486 | Acinetobacter baumannii AB307-0294 | chromosome (NZ_CP001172) | 136278..137621 (-) | 447062379 |
Showing 1 to 3 of 3 rows
Experimental investigation has been performed.
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Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||