Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS00275 experimental
T6SS type Type i3
Strain Paraburkholderia phymatum STM815
Replicon (RefSeq) plasmid pBPHY01 (NC_010625)
Location 654398..678783
Function anti-bacterial
Comment Both T6SSs of P. phymatum play an important role in the competition against other bacteria.
T6SS-3 expression is maximal in the stationary phase when succinate is used as carbon source.
References
[1] de Campos SB, Lardi M, Gandolfi A, Eberl L, Pessi G. et al (2017) Mutations in Two Paraburkholderia phymatum Type VI Secretion Systems Cause Reduced Fitness in Interbacterial Competition.. Front Microbiol. 2.050694444. [PudMed:29312183]
[2] Hug S, Liu Y, Heiniger B, Bailly A, Ahrens CH, Eberl L, Pessi G. et al (2021) Differential Expression of Paraburkholderia phymatum Type VI Secretion Systems (T6SS) Suggests a Role of T6SS-b in Early Symbiotic Interaction.. Front Plant Sci. 12:699590. [PudMed:34394152]
experimental Experimental investigation has been performed.

T6SS components and genome coordinates

ComponentPAARTagJTssATssBTssCTssDTssETssFTssGTssHTssITssJTssKTssLTssM
Number111111111111121


Component ID Component Locus tag (Gene) Coordinate Strand Size (bp) NCBI ID Product
BPHY_RS30465 649579..650190 + 612 WP_012405319.1 NIPSNAP family protein
BPHY_RS30470 650235..651071 + 837 WP_012405320.1 sugar phosphate isomerase/epimerase
BPHY_RS30475 651189..652586 + 1398 WP_012405321.1 MFS transporter
BPHY_RS30480 652685..653527 + 843 WP_012405322.1 IclR family transcriptional regulator
T6CP002750 TssL BPHY_RS30485 654398..655630 - 1233 WP_012405323.1 DotU/TssL family secretion system protein
T6CP002751 TssM BPHY_RS30490 (tssM) 655657..659703 - 4047 WP_012405324.1 type VI secretion system membrane subunit TssM
T6CP002752 TssL BPHY_RS30495 (tssL) 659734..661077 - 1344 WP_012405325.1 type VI secretion system protein TssL, long form
T6CP002753 TssK BPHY_RS30500 (tssK) 661145..662491 - 1347 WP_012405326.1 type VI secretion system baseplate subunit TssK
T6CP002754 TssJ BPHY_RS30505 (tssJ) 662515..663021 - 507 WP_012405327.1 type VI secretion system lipoprotein TssJ
T6CP002755 TssD BPHY_RS30510 663139..663624 - 486 WP_012405328.1 type VI secretion system tube protein Hcp
T6CP002756 TssC BPHY_RS30515 (tssC) 663703..665196 - 1494 WP_012405329.1 type VI secretion system contractile sheath large subunit
T6CP002757 TssB BPHY_RS30520 (tssB) 665221..665754 - 534 WP_012405330.1 type VI secretion system contractile sheath small subunit
T6CP002758 TssH BPHY_RS30525 (tssH) 665804..668524 - 2721 WP_012405331.1 type VI secretion system ATPase TssH
BPHY_RS38875 668949..669632 + 684 WP_012405332.1 TagK domain-containing protein
T6CP012758 TagJ BPHY_RS30535 669629..670495 + 867 WP_012405333.1 virulence protein SciE type
T6CP002759 TssE BPHY_RS30540 (tssE) 670482..671033 + 552 WP_012405334.1 type VI secretion system baseplate subunit TssE
T6CP002760 TssF BPHY_RS30545 (tssF) 671060..672949 + 1890 WP_012405335.1 type VI secretion system baseplate subunit TssF
T6CP002761 TssG BPHY_RS30550 (tssG) 672949..674037 + 1089 WP_012405336.1 type VI secretion system baseplate subunit TssG
T6CP002762 TssA BPHY_RS30555 674034..675119 + 1086 WP_012405337.1 ImpA family type VI secretion system protein
BPHY_RS30560 675123..675779 + 657 WP_012405338.1 hypothetical protein
BPHY_RS40095 675751..676455 + 705 WP_157686867.1 hypothetical protein
T6CP002763 TssI BPHY_RS30565 (tssI) 676639..678783 + 2145 WP_012405340.1 type VI secretion system tip protein VgrG
BPHY_RS38880 678826..681066 + 2241 WP_012405341.1 M23 family metallopeptidase
BPHY_RS40100 681063..681656 + 594 WP_012405342.1 hypothetical protein
T6CP011673 PAAR BPHY_RS40105 681696..681950 + 255 WP_012405343.1 PAAR domain-containing protein
BPHY_RS38885 681982..682656 + 675 WP_012405344.1 hypothetical protein
BPHY_RS30575 682617..683600 + 984 WP_052306199.1 M23 family metallopeptidase
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Regulator ID Locus tag (Gene) Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Effector ID Locus tag (Gene) Classification Cognate immunity protein Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Immunity protein ID Locus tag (Gene) Cognate effector Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
Accessory protein ID Locus tag (Gene) Type             Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Related structure protein Related effector