Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01063  |
| T6SS type | Type i3 |
| Strain | Bradyrhizobium japonicum strain J5 |
| Replicon (RefSeq) | chromosome (NZ_CP017637) |
| Location | 3553506..3574647 |
| Function | anti-bacterial |
| Comment | Wild-type B. cepacia T6SS is functional and kills the effector-immunity deletion mutant. |
| References | [1] Burkinshaw BJ, Liang X, Wong M, Le ANH, Lam L, Dong TG et al (2018) A type VI secretion system effector delivery mechanism dependent on PAAR and a chaperone-co-chaperone complex. Nat Microbiol. 3(5):632-640. [PudMed:29632369] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| BKD09_RS17190 | 3548905..3549852 | - | 948 | WP_071911355.1 | hypothetical protein | ||
| BKD09_RS17195 | 3550116..3550880 | - | 765 | WP_155795572.1 | hypothetical protein | ||
| BKD09_RS17200 | 3551196..3551825 | + | 630 | WP_071917287.1 | hypothetical protein | ||
| BKD09_RS17205 | 3551914..3553515 | - | 1602 | WP_155795010.1 | class I SAM-dependent methyltransferase | ||
| T6CP013729 | TssH | BKD09_RS17210 (tssH) | 3553506..3556145 | - | 2640 | WP_071911359.1 | type VI secretion system ATPase TssH |
| T6CP013730 | TssG | BKD09_RS17215 (tssG) | 3556243..3557307 | - | 1065 | WP_071911361.1 | type VI secretion system baseplate subunit TssG |
| T6CP013731 | TssF | BKD09_RS17220 (tssF) | 3557271..3559238 | - | 1968 | WP_071911363.1 | type VI secretion system baseplate subunit TssF |
| T6CP013732 | TssE | BKD09_RS17225 (tssE) | 3559240..3559788 | - | 549 | WP_155795011.1 | type VI secretion system baseplate subunit TssE |
| T6CP013733 | TssD | BKD09_RS17235 | 3559970..3560455 | - | 486 | WP_014493489.1 | type VI secretion system tube protein Hcp |
| T6CP013734 | TssC | BKD09_RS17240 (tssC) | 3560504..3562006 | - | 1503 | WP_071911365.1 | type VI secretion system contractile sheath large subunit |
| T6CP013735 | TssB | BKD09_RS17245 (tssB) | 3562023..3562550 | - | 528 | WP_028156839.1 | type VI secretion system contractile sheath small subunit |
| BKD09_RS17250 | 3562678..3564018 | - | 1341 | WP_155795012.1 | type VI secretion system ImpA family N-terminal domain-containing protein | ||
| T6CP013736 | TssI | BKD09_RS17255 (tssI) | 3564344..3566212 | + | 1869 | WP_071911367.1 | type VI secretion system tip protein VgrG |
| BKD09_RS17260 | 3566218..3566781 | + | 564 | WP_038935432.1 | hypothetical protein | ||
| BKD09_RS17265 (tagH) | 3566791..3568152 | + | 1362 | WP_155795013.1 | type VI secretion system-associated FHA domain protein TagH | ||
| T6CP013737 | TssK | BKD09_RS17270 (tssK) | 3568189..3569538 | + | 1350 | WP_155795014.1 | type VI secretion system baseplate subunit TssK |
| T6CP013738 | TssL | BKD09_RS17275 (tssL) | 3569535..3571061 | + | 1527 | WP_071911373.1 | type VI secretion system protein TssL, long form |
| T6CP013739 | TssM | BKD09_RS17280 (tssM) | 3571105..3574647 | + | 3543 | WP_071911375.1 | type VI secretion system membrane subunit TssM |
| BKD09_RS17285 (tagF) | 3574644..3575345 | + | 702 | WP_071911376.1 | type VI secretion system-associated protein TagF | ||
| BKD09_RS17290 | 3575352..3576128 | + | 777 | WP_014493500.1 | protein phosphatase 2C domain-containing protein | ||
| BKD09_RS17295 | 3576125..3577933 | + | 1809 | WP_071911378.1 | serine/threonine protein kinase | ||
| BKD09_RS17300 | 3577943..3579055 | - | 1113 | WP_155795015.1 | DUF4424 domain-containing protein | ||
| BKD09_RS17305 | 3579025..3579315 | - | 291 | WP_014493503.1 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF01811 |
RS15455 (TseT) | Tde | IMU00347 |
Bradyrhizobium japonicum strain J5 | chromosome (NZ_CP017637) | 3215663..3216637 (-) | 1173687256 |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| IMU00347 |
RS38465 (TsiT) | EFF01811 |
Bradyrhizobium japonicum strain J5 | chromosome (NZ_CP017637) | 8075210..8076133 (+) | 1110689930 |
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|