Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00164  |
| T6SS type | Type i3 |
| Strain | Acidovorax citrulli AAC00-1 |
| Replicon (RefSeq) | chromosome (NC_008752) |
| Location | 1617808..1647773 |
| Function | anti-bacterial; anti-eukaryotic |
| Comment | T6SS plays a role in BFB seed-to-seedling transmission, melon seed colonization and biofilm formation. |
| References | [1] Tian Y et al (2014) The Type VI Protein Secretion System Contributes to Biofilm Formation and Seed-to-Seedling Transmission of Acidovorax citrulli on melon. Mol Plant Pathol. 16(1):38-47. [PudMed:24863458] [2] Boyer F et al (2009) Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 0.488888889. [PudMed:19284603] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | FHA | TagJ | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| AAVE_RS07265 | 1614190..1615446 | - | 1257 | WP_011794603.1 | efflux RND transporter periplasmic adaptor subunit | ||
| AAVE_RS07270 (hpnC) | 1615609..1616532 | + | 924 | WP_081436500.1 | squalene synthase HpnC | ||
| AAVE_RS07275 | 1616619..1617287 | - | 669 | WP_011794605.1 | hypothetical protein | ||
| T6CP001604 | TssD | AAVE_RS07280 | 1617808..1618290 | - | 483 | WP_011794606.1 | type VI secretion system tube protein Hcp |
| AAVE_RS07285 | 1618859..1620844 | + | 1986 | WP_011794607.1 | serine/threonine protein kinase | ||
| AAVE_RS07290 | 1620951..1621451 | + | 501 | WP_011794608.1 | TssQ family T6SS-associated lipoprotein | ||
| T6CP011374 | FHA | AAVE_RS07295 (tagH) | 1621473..1623806 | + | 2334 | WP_011794609.1 | type VI secretion system-associated FHA domain protein TagH |
| AAVE_RS07300 | 1623803..1624591 | + | 789 | WP_041827282.1 | serine/threonine-protein phosphatase | ||
| T6CP001605 | TssJ | AAVE_RS07305 (tssJ) | 1624635..1625198 | + | 564 | WP_011794611.1 | type VI secretion system lipoprotein TssJ |
| T6CP001606 | TssK | AAVE_RS07310 (tssK) | 1625240..1626574 | + | 1335 | WP_011794612.1 | type VI secretion system baseplate subunit TssK |
| T6CP001607 | TssL | AAVE_RS07315 | 1626589..1627941 | + | 1353 | WP_085947483.1 | DotU family type VI secretion system protein |
| T6CP001608 | TssM | AAVE_RS07320 (tssM) | 1627945..1631574 | + | 3630 | WP_011794614.1 | type VI secretion system membrane subunit TssM |
| AAVE_RS07325 (tagF) | 1631574..1632269 | + | 696 | WP_048857798.1 | type VI secretion system-associated protein TagF | ||
| T6CP001609 | TssA | AAVE_RS07330 (tssA) | 1632316..1633356 | + | 1041 | WP_011794616.1 | type VI secretion system protein TssA |
| T6CP001610 | TssB | AAVE_RS07335 (tssB) | 1633519..1634067 | + | 549 | WP_011794617.1 | type VI secretion system contractile sheath small subunit |
| T6CP001611 | TssC | AAVE_RS07340 (tssC) | 1634081..1635580 | + | 1500 | WP_011794618.1 | type VI secretion system contractile sheath large subunit |
| T6CP012735 | TagJ | AAVE_RS07345 | 1635702..1636490 | + | 789 | WP_017438650.1 | virulence protein SciE type |
| T6CP001612 | TssE | AAVE_RS07350 (tssE) | 1636507..1637028 | + | 522 | WP_011794620.1 | type VI secretion system baseplate subunit TssE |
| T6CP001613 | TssF | AAVE_RS07355 (tssF) | 1637101..1638975 | + | 1875 | WP_011794621.1 | type VI secretion system baseplate subunit TssF |
| T6CP001614 | TssG | AAVE_RS07360 (tssG) | 1638972..1640138 | + | 1167 | WP_011794622.1 | type VI secretion system baseplate subunit TssG |
| T6CP001615 | TssH | AAVE_RS07365 (tssH) | 1640211..1642988 | + | 2778 | WP_011794623.1 | type VI secretion system ATPase TssH |
| AAVE_RS07375 | 1643375..1644013 | + | 639 | WP_011794624.1 | hypothetical protein | ||
| AAVE_RS07380 | 1644043..1644546 | + | 504 | WP_041827872.1 | M48 family metallopeptidase | ||
| AAVE_RS07385 | 1644568..1646817 | - | 2250 | WP_011794626.1 | xanthine dehydrogenase family protein molybdopterin-binding subunit | ||
| AAVE_RS07390 | 1646823..1647773 | - | 951 | WP_011794627.1 | xanthine dehydrogenase family protein subunit M | ||
| AAVE_RS07395 (paoA) | 1647777..1648395 | - | 619 | pseudogene | aldehyde dehydrogenase iron-sulfur subunit | ||
| AAVE_RS07400 (murI) | 1648610..1649500 | - | 891 | WP_011794628.1 | glutamate racemase | ||
| AAVE_RS07405 | 1649597..1651156 | - | 1560 | WP_011794629.1 | fumarate hydratase |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF76654 |
AAVE_RS02475 (RhsB) | - | IMU38225 ; IMU38226 |
Acidovorax citrulli AAC00-1 | chromosome (NC_008752) | 538874..543688 (+) | WP_011793679.1 |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| IMU38225 |
AAVE_RS02480 (RimB1) | EFF76654 |
Acidovorax citrulli AAC00-1 | chromosome (NC_008752) | 543696..544019 (+) | WP_041827204.1 |
| IMU38226 |
AAVE_RS25260 (RimB2) | EFF76654 |
Acidovorax citrulli AAC00-1 | chromosome (NC_008752) | 544063..544386 (+) | WP_128098957.1 |
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|