Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS00164 experimental
T6SS type Type i3
Strain Acidovorax citrulli AAC00-1
Replicon (RefSeq) chromosome (NC_008752)
Location 1617808..1647773
Function anti-bacterial; anti-eukaryotic
Comment T6SS plays a role in BFB seed-to-seedling transmission, melon seed colonization and biofilm formation.
References
[1] Tian Y et al (2014) The Type VI Protein Secretion System Contributes to Biofilm Formation and Seed-to-Seedling Transmission of Acidovorax citrulli on melon. Mol Plant Pathol. 16(1):38-47. [PudMed:24863458]
[2] Boyer F et al (2009) Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 0.488888889. [PudMed:19284603]
experimental Experimental investigation has been performed.

T6SS components and genome coordinates

ComponentFHATagJTssATssBTssCTssDTssETssFTssGTssHTssJTssKTssLTssM
Number11111111111111


Component ID Component Locus tag (Gene) Coordinate Strand Size (bp) NCBI ID Product
AAVE_RS07265 1614190..1615446 - 1257 WP_011794603.1 efflux RND transporter periplasmic adaptor subunit
AAVE_RS07270 (hpnC) 1615609..1616532 + 924 WP_081436500.1 squalene synthase HpnC
AAVE_RS07275 1616619..1617287 - 669 WP_011794605.1 hypothetical protein
T6CP001604 TssD AAVE_RS07280 1617808..1618290 - 483 WP_011794606.1 type VI secretion system tube protein Hcp
AAVE_RS07285 1618859..1620844 + 1986 WP_011794607.1 serine/threonine protein kinase
AAVE_RS07290 1620951..1621451 + 501 WP_011794608.1 TssQ family T6SS-associated lipoprotein
T6CP011374 FHA AAVE_RS07295 (tagH) 1621473..1623806 + 2334 WP_011794609.1 type VI secretion system-associated FHA domain protein TagH
AAVE_RS07300 1623803..1624591 + 789 WP_041827282.1 serine/threonine-protein phosphatase
T6CP001605 TssJ AAVE_RS07305 (tssJ) 1624635..1625198 + 564 WP_011794611.1 type VI secretion system lipoprotein TssJ
T6CP001606 TssK AAVE_RS07310 (tssK) 1625240..1626574 + 1335 WP_011794612.1 type VI secretion system baseplate subunit TssK
T6CP001607 TssL AAVE_RS07315 1626589..1627941 + 1353 WP_085947483.1 DotU family type VI secretion system protein
T6CP001608 TssM AAVE_RS07320 (tssM) 1627945..1631574 + 3630 WP_011794614.1 type VI secretion system membrane subunit TssM
AAVE_RS07325 (tagF) 1631574..1632269 + 696 WP_048857798.1 type VI secretion system-associated protein TagF
T6CP001609 TssA AAVE_RS07330 (tssA) 1632316..1633356 + 1041 WP_011794616.1 type VI secretion system protein TssA
T6CP001610 TssB AAVE_RS07335 (tssB) 1633519..1634067 + 549 WP_011794617.1 type VI secretion system contractile sheath small subunit
T6CP001611 TssC AAVE_RS07340 (tssC) 1634081..1635580 + 1500 WP_011794618.1 type VI secretion system contractile sheath large subunit
T6CP012735 TagJ AAVE_RS07345 1635702..1636490 + 789 WP_017438650.1 virulence protein SciE type
T6CP001612 TssE AAVE_RS07350 (tssE) 1636507..1637028 + 522 WP_011794620.1 type VI secretion system baseplate subunit TssE
T6CP001613 TssF AAVE_RS07355 (tssF) 1637101..1638975 + 1875 WP_011794621.1 type VI secretion system baseplate subunit TssF
T6CP001614 TssG AAVE_RS07360 (tssG) 1638972..1640138 + 1167 WP_011794622.1 type VI secretion system baseplate subunit TssG
T6CP001615 TssH AAVE_RS07365 (tssH) 1640211..1642988 + 2778 WP_011794623.1 type VI secretion system ATPase TssH
AAVE_RS07375 1643375..1644013 + 639 WP_011794624.1 hypothetical protein
AAVE_RS07380 1644043..1644546 + 504 WP_041827872.1 M48 family metallopeptidase
AAVE_RS07385 1644568..1646817 - 2250 WP_011794626.1 xanthine dehydrogenase family protein molybdopterin-binding subunit
AAVE_RS07390 1646823..1647773 - 951 WP_011794627.1 xanthine dehydrogenase family protein subunit M
AAVE_RS07395 (paoA) 1647777..1648395 - 619 pseudogene aldehyde dehydrogenase iron-sulfur subunit
AAVE_RS07400 (murI) 1648610..1649500 - 891 WP_011794628.1 glutamate racemase
AAVE_RS07405 1649597..1651156 - 1560 WP_011794629.1 fumarate hydratase
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Regulator ID Locus tag (Gene) Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Effector ID Locus tag (Gene) Classification Cognate immunity protein Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID
EFF76654 experimental AAVE_RS02475 (RhsB) - IMU38225 experimental; IMU38226 experimental Acidovorax citrulli AAC00-1 chromosome (NC_008752) 538874..543688 (+) WP_011793679.1

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Immunity protein ID Locus tag (Gene) Cognate effector Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID
IMU38225 experimental AAVE_RS02480 (RimB1) EFF76654 experimental Acidovorax citrulli AAC00-1 chromosome (NC_008752) 543696..544019 (+) WP_041827204.1
IMU38226 experimental AAVE_RS25260 (RimB2) EFF76654 experimental Acidovorax citrulli AAC00-1 chromosome (NC_008752) 544063..544386 (+) WP_128098957.1

experimental Experimental investigation has been performed.
Accessory protein ID Locus tag (Gene) Type             Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Related structure protein Related effector