Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   U0N78_RS00440 Genome accession   NZ_CP140109
Coordinates   78714..79184 (+) Length   156 a.a.
NCBI ID   WP_043025097.1    Uniprot ID   A0A0Z8FNC4
Organism   Streptococcus suis strain 2022WUSS148     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 73714..84184
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS00405 (U0N78_00405) cinA 73815..74996 (+) 1182 WP_043025095.1 competence/damage-inducible protein A Machinery gene
  U0N78_RS00410 (U0N78_00410) recA 75048..76199 (+) 1152 WP_004195473.1 recombinase RecA Machinery gene
  U0N78_RS00415 (U0N78_00415) spx 76359..76757 (+) 399 WP_004195475.1 transcriptional regulator Spx -
  U0N78_RS00420 (U0N78_00420) - 76864..77130 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  U0N78_RS00425 (U0N78_00425) ruvX 77130..77549 (+) 420 WP_174850213.1 Holliday junction resolvase RuvX -
  U0N78_RS00430 (U0N78_00430) - 77561..77878 (+) 318 WP_004195480.1 DUF1292 domain-containing protein -
  U0N78_RS00435 (U0N78_00435) - 78074..78619 (+) 546 WP_228475292.1 nucleotidyltransferase family protein -
  U0N78_RS00440 (U0N78_00440) comX/sigX 78714..79184 (+) 471 WP_043025097.1 sigma-70 family RNA polymerase sigma factor Regulator
  U0N78_RS00445 (U0N78_00445) rpsJ 79450..79758 (+) 309 WP_002939332.1 30S ribosomal protein S10 -
  U0N78_RS00450 (U0N78_00450) rplC 79972..80598 (+) 627 WP_011921686.1 50S ribosomal protein L3 -
  U0N78_RS00455 (U0N78_00455) rplD 80623..81246 (+) 624 WP_004195490.1 50S ribosomal protein L4 -
  U0N78_RS00460 (U0N78_00460) - 81246..81545 (+) 300 WP_004195491.1 50S ribosomal protein L23 -
  U0N78_RS00465 (U0N78_00465) rplB 81563..82396 (+) 834 WP_002936663.1 50S ribosomal protein L2 -
  U0N78_RS00470 (U0N78_00470) rpsS 82647..82928 (+) 282 WP_000533766.1 30S ribosomal protein S19 -
  U0N78_RS00475 (U0N78_00475) rplV 82946..83290 (+) 345 WP_002936662.1 50S ribosomal protein L22 -
  U0N78_RS00480 (U0N78_00480) rpsC 83303..83956 (+) 654 WP_002936661.1 30S ribosomal protein S3 -

Sequence

Protein


Download         Length: 156 a.a.        Molecular weight: 19017.75 Da        Isoelectric Point: 9.2450

>NTDB_id=912556 U0N78_RS00440 WP_043025097.1 78714..79184(+) (comX/sigX) [Streptococcus suis strain 2022WUSS148]
MKFEKVYASVKGIVNKARKEFYIKLWDREDWDQEGMMTLFELLEDQPWLADEQEQLYCYFKVKFRNRVKDRVRRQESQKR
KFDRMPHEDIHDLSHGIQSPGLVNDELLMLRGALRDYRKNLSDDQLVKYEKLISGQSFNGRKNMLRDLQEHLKDFR

Nucleotide


Download         Length: 471 bp        

>NTDB_id=912556 U0N78_RS00440 WP_043025097.1 78714..79184(+) (comX/sigX) [Streptococcus suis strain 2022WUSS148]
ATGAAATTTGAAAAGGTCTATGCTAGCGTAAAAGGGATTGTCAACAAGGCTCGAAAAGAGTTTTATATTAAGCTCTGGGA
CAGGGAAGATTGGGATCAAGAGGGCATGATGACCTTATTTGAATTGTTGGAAGATCAACCGTGGTTAGCTGATGAGCAAG
AACAGTTGTATTGCTATTTTAAAGTGAAATTTAGAAATCGGGTCAAAGACCGCGTACGCAGACAAGAAAGTCAGAAGCGT
AAGTTTGATCGTATGCCGCATGAAGATATTCATGATTTATCTCACGGTATACAATCGCCAGGTTTAGTCAATGATGAGCT
GTTAATGTTGAGAGGGGCCTTGAGAGATTATCGTAAGAATCTCAGCGATGACCAGCTTGTGAAGTATGAAAAACTAATTA
GTGGTCAGAGTTTCAATGGTCGTAAGAATATGCTTAGGGATCTACAAGAACATTTAAAGGACTTTCGATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8FNC4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus suis D9

87.821

100

0.878
  comX/sigX Streptococcus suis isolate S10

87.179

100

0.872
  comX/sigX Streptococcus suis P1/7

87.179

100

0.872
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

49.677

99.359

0.494
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

49.677

99.359

0.494
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

43.791

98.077

0.429
  comX/sigX Streptococcus mutans UA159

43.506

98.718

0.429
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

42.038

100

0.423
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

43.137

98.077

0.423
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

42.484

98.077

0.417
  comX/comX1 Streptococcus pneumoniae Rx1

43.046

96.795

0.417
  comX/comX2 Streptococcus pneumoniae D39

43.046

96.795

0.417
  comX/comX1 Streptococcus pneumoniae D39

43.046

96.795

0.417
  comX/comX2 Streptococcus pneumoniae R6

43.046

96.795

0.417
  comX/comX1 Streptococcus pneumoniae R6

43.046

96.795

0.417
  comX/comX2 Streptococcus pneumoniae Rx1

43.046

96.795

0.417
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

41.83

98.077

0.41
  comX/comX1 Streptococcus pneumoniae TIGR4

42.384

96.795

0.41
  comX/comX2 Streptococcus pneumoniae TIGR4

42.384

96.795

0.41
  comX Streptococcus thermophilus LMG 18311

41.176

98.077

0.404
  comX Streptococcus thermophilus LMD-9

41.176

98.077

0.404
  comX Streptococcus salivarius SK126

40.523

98.077

0.397
  comX/sigX Streptococcus salivarius strain HSISS4

40.523

98.077

0.397
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

40.667

96.154

0.391
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

40.667

96.154

0.391
  comX Streptococcus sobrinus strain NIDR 6715-7

39.216

98.077

0.385
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

96.154

0.385
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

96.154

0.385
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

96.154

0.385
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

96.154

0.385