Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   U0N78_RS00405 Genome accession   NZ_CP140109
Coordinates   73815..74996 (+) Length   393 a.a.
NCBI ID   WP_043025095.1    Uniprot ID   A0A0Z8H752
Organism   Streptococcus suis strain 2022WUSS148     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 68815..79996
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS00390 (U0N78_00390) mutL 70038..71975 (+) 1938 WP_256769046.1 DNA mismatch repair endonuclease MutL -
  U0N78_RS00395 (U0N78_00395) ruvA 72014..72604 (+) 591 WP_043025669.1 Holliday junction branch migration protein RuvA -
  U0N78_RS00400 (U0N78_00400) - 73209..73778 (+) 570 WP_043025096.1 DNA-3-methyladenine glycosylase I -
  U0N78_RS00405 (U0N78_00405) cinA 73815..74996 (+) 1182 WP_043025095.1 competence/damage-inducible protein A Machinery gene
  U0N78_RS00410 (U0N78_00410) recA 75048..76199 (+) 1152 WP_004195473.1 recombinase RecA Machinery gene
  U0N78_RS00415 (U0N78_00415) spx 76359..76757 (+) 399 WP_004195475.1 transcriptional regulator Spx -
  U0N78_RS00420 (U0N78_00420) - 76864..77130 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  U0N78_RS00425 (U0N78_00425) ruvX 77130..77549 (+) 420 WP_174850213.1 Holliday junction resolvase RuvX -
  U0N78_RS00430 (U0N78_00430) - 77561..77878 (+) 318 WP_004195480.1 DUF1292 domain-containing protein -
  U0N78_RS00435 (U0N78_00435) - 78074..78619 (+) 546 WP_228475292.1 nucleotidyltransferase family protein -
  U0N78_RS00440 (U0N78_00440) comX/sigX 78714..79184 (+) 471 WP_043025097.1 sigma-70 family RNA polymerase sigma factor Regulator
  U0N78_RS00445 (U0N78_00445) rpsJ 79450..79758 (+) 309 WP_002939332.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42919.83 Da        Isoelectric Point: 4.4531

>NTDB_id=912554 U0N78_RS00405 WP_043025095.1 73815..74996(+) (cinA) [Streptococcus suis strain 2022WUSS148]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVASQRSDLVILCGGLGPTEDDLTKQT
LAAFLGRKLVFDEKAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKAISQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKSESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=912554 U0N78_RS00405 WP_043025095.1 73815..74996(+) (cinA) [Streptococcus suis strain 2022WUSS148]
ATGAAAGCAGAACTAATCGCCGTCGGAACCGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTATCTGTACTGG
AAGTAGCCAGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACT
TTGGCAGCCTTCTTAGGTAGAAAATTGGTCTTTGATGAAAAAGCCATGGCAAAATTAGACCGCTTCTTTGCCAGCCGACC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGAATTGG
CGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGATCAGCCAAGAAGAGGCAAATCTACGTTTAAATCAGTTGGAAGAGGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAATCGGAATCGACAGAGGACAA
TGTACTTGCAAAAGTATACCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8H752

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

95.674

100

0.957
  cinA Streptococcus mitis SK321

56.01

100

0.593
  cinA Streptococcus pneumoniae TIGR4

56.01

100

0.593
  cinA Streptococcus pneumoniae Rx1

56.01

100

0.593
  cinA Streptococcus pneumoniae R6

56.01

100

0.593
  cinA Streptococcus mutans UA159

56.691

100

0.593
  cinA Streptococcus mitis NCTC 12261

55.769

100

0.59
  cinA Streptococcus pneumoniae D39

55.769

100

0.59
  cinA Bacillus subtilis subsp. subtilis str. 168

48.208

78.117

0.377