Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   PW220_RS00385 Genome accession   NZ_CP118734
Coordinates   65544..66017 (+) Length   157 a.a.
NCBI ID   WP_238139119.1    Uniprot ID   -
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 60544..71017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS00355 (PW220_00355) cinA 60993..62174 (+) 1182 WP_248054905.1 competence/damage-inducible protein A Machinery gene
  PW220_RS00360 (PW220_00360) recA 62226..63377 (+) 1152 WP_248054908.1 recombinase RecA Machinery gene
  PW220_RS00365 (PW220_00365) spx 63536..63934 (+) 399 WP_029177692.1 transcriptional regulator Spx -
  PW220_RS00370 (PW220_00370) - 64040..64306 (+) 267 WP_029177693.1 IreB family regulatory phosphoprotein -
  PW220_RS00375 (PW220_00375) ruvX 64306..64725 (+) 420 WP_248054910.1 Holliday junction resolvase RuvX -
  PW220_RS00380 (PW220_00380) - 64737..65054 (+) 318 WP_004195480.1 DUF1292 domain-containing protein -
  PW220_RS00385 (PW220_00385) comX/sigX 65544..66017 (+) 474 WP_238139119.1 sigma-70 family RNA polymerase sigma factor Regulator
  PW220_RS00390 (PW220_00390) rpsJ 66283..66591 (+) 309 WP_002939332.1 30S ribosomal protein S10 -
  PW220_RS00395 (PW220_00395) rplC 66803..67429 (+) 627 WP_011921686.1 50S ribosomal protein L3 -
  PW220_RS00400 (PW220_00400) rplD 67454..68077 (+) 624 WP_004195490.1 50S ribosomal protein L4 -
  PW220_RS00405 (PW220_00405) - 68077..68376 (+) 300 WP_004195491.1 50S ribosomal protein L23 -
  PW220_RS00410 (PW220_00410) rplB 68394..69227 (+) 834 WP_002936663.1 50S ribosomal protein L2 -
  PW220_RS00415 (PW220_00415) rpsS 69329..69610 (+) 282 WP_000533766.1 30S ribosomal protein S19 -
  PW220_RS00420 (PW220_00420) rplV 69628..69972 (+) 345 WP_002936662.1 50S ribosomal protein L22 -
  PW220_RS00425 (PW220_00425) rpsC 69985..70638 (+) 654 WP_044689746.1 30S ribosomal protein S3 -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19244.12 Da        Isoelectric Point: 8.7475

>NTDB_id=794660 PW220_RS00385 WP_238139119.1 65544..66017(+) (comX/sigX) [Streptococcus iners subsp. hyiners strain 29892]
MMEFEKMYDSVKGIVNKARKEFYIKLWDRDDWEQEGMITLFELLEDQPWLIGERAQLYCYFKVKFRNRIKDYVRRQESKK
RKFDRMPHEDIHELSQVIQSPGLVNDELLLLRGALRDYRKNLSMDQLENYEKLISGQSFNGRKNMLRDLQEHLKDFR

Nucleotide


Download         Length: 474 bp        

>NTDB_id=794660 PW220_RS00385 WP_238139119.1 65544..66017(+) (comX/sigX) [Streptococcus iners subsp. hyiners strain 29892]
ATGATGGAATTTGAAAAGATGTATGATAGCGTAAAAGGAATTGTTAACAAAGCTCGTAAAGAGTTTTATATCAAACTGTG
GGACAGAGATGACTGGGAGCAGGAAGGCATGATAACCTTGTTTGAATTATTGGAGGATCAACCATGGTTGATTGGGGAAA
GAGCCCAGTTGTATTGTTATTTCAAGGTTAAATTCAGAAATCGGATTAAGGACTATGTTCGCAGACAGGAAAGTAAAAAG
CGCAAGTTTGACCGAATGCCTCATGAAGACATACATGAACTATCACAAGTAATACAATCGCCAGGTTTAGTCAATGACGA
GCTATTGTTGTTGAGAGGTGCCTTGAGAGATTATCGGAAAAATTTGTCCATGGACCAATTGGAAAATTATGAAAAACTAA
TTAGTGGTCAGAGTTTCAATGGTCGTAAGAATATGCTTAGAGATTTACAAGAACATTTAAAGGACTTTCGATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus suis D9

84.615

99.363

0.841
  comX/sigX Streptococcus suis isolate S10

83.974

99.363

0.834
  comX/sigX Streptococcus suis P1/7

83.974

99.363

0.834
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

47.742

98.726

0.471
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

47.742

98.726

0.471
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

45.098

97.452

0.439
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

44.444

97.452

0.433
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

44.444

97.452

0.433
  comX/sigX Streptococcus mutans UA159

43.226

98.726

0.427
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

43.791

97.452

0.427
  comX/comX2 Streptococcus pneumoniae TIGR4

44.371

96.178

0.427
  comX/comX1 Streptococcus pneumoniae TIGR4

44.371

96.178

0.427
  comX/comX1 Streptococcus pneumoniae R6

43.709

96.178

0.42
  comX/comX2 Streptococcus pneumoniae Rx1

43.709

96.178

0.42
  comX/comX1 Streptococcus pneumoniae Rx1

43.709

96.178

0.42
  comX/comX2 Streptococcus pneumoniae D39

43.709

96.178

0.42
  comX/comX1 Streptococcus pneumoniae D39

43.709

96.178

0.42
  comX/comX2 Streptococcus pneumoniae R6

43.709

96.178

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

98.726

0.395
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

40

98.726

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

40

98.726

0.395
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

98.726

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

98.726

0.395
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

98.726

0.395
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.854

100

0.389
  comX Streptococcus thermophilus LMG 18311

39.869

97.452

0.389
  comX Streptococcus thermophilus LMD-9

39.869

97.452

0.389
  comX/sigX Streptococcus salivarius strain HSISS4

39.216

97.452

0.382
  comX Streptococcus salivarius SK126

39.216

97.452

0.382
  comX Streptococcus sobrinus strain NIDR 6715-7

37.255

97.452

0.363