Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PW220_RS00355 Genome accession   NZ_CP118734
Coordinates   60993..62174 (+) Length   393 a.a.
NCBI ID   WP_248054905.1    Uniprot ID   A0AA97A215
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 55993..67174
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS00330 (PW220_00330) - 58002..58367 (+) 366 WP_248054896.1 helix-turn-helix domain-containing protein -
  PW220_RS00335 (PW220_00335) - 58382..59029 (+) 648 WP_248054898.1 CPBP family intramembrane glutamic endopeptidase -
  PW220_RS00340 (PW220_00340) ruvA 59108..59698 (+) 591 WP_248054899.1 Holliday junction branch migration protein RuvA -
  PW220_RS00345 (PW220_00345) - 59707..60348 (+) 642 WP_248054901.1 hypothetical protein -
  PW220_RS00350 (PW220_00350) - 60366..60923 (+) 558 WP_248054903.1 DNA-3-methyladenine glycosylase I -
  PW220_RS00355 (PW220_00355) cinA 60993..62174 (+) 1182 WP_248054905.1 competence/damage-inducible protein A Machinery gene
  PW220_RS00360 (PW220_00360) recA 62226..63377 (+) 1152 WP_248054908.1 recombinase RecA Machinery gene
  PW220_RS00365 (PW220_00365) spx 63536..63934 (+) 399 WP_029177692.1 transcriptional regulator Spx -
  PW220_RS00370 (PW220_00370) - 64040..64306 (+) 267 WP_029177693.1 IreB family regulatory phosphoprotein -
  PW220_RS00375 (PW220_00375) ruvX 64306..64725 (+) 420 WP_248054910.1 Holliday junction resolvase RuvX -
  PW220_RS00380 (PW220_00380) - 64737..65054 (+) 318 WP_004195480.1 DUF1292 domain-containing protein -
  PW220_RS00385 (PW220_00385) comX/sigX 65544..66017 (+) 474 WP_238139119.1 sigma-70 family RNA polymerase sigma factor Regulator
  PW220_RS00390 (PW220_00390) rpsJ 66283..66591 (+) 309 WP_002939332.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42844.67 Da        Isoelectric Point: 4.5664

>NTDB_id=794658 PW220_RS00355 WP_248054905.1 60993..62174(+) (cinA) [Streptococcus iners subsp. hyiners strain 29892]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEKRLLSVLEVASKRSELVILCGGLGPTEDDLTKQT
LAAFLGRKLVFDEKAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGLIEQAGVTYVVLPGPPSELRAM
FTESLQPLLNQSSQQLYSRVLRFFGIGESQLVTILADLIDKQTDPTLAPYAKVGEVTLRLSTKANSQEEADFRLKQLEED
ILQRDKLREYFYAYGEENSLVQTVAERLVEKNKSIAIVEQGTGGLLQSEVSLALTGQPYFSGGQVIGQLGTESGRCSEEA
DGIREELQADLGLAVSVLIKSESTEDNVLAKVYIALASTSGISQKEVDLGGYSWQHIRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=794658 PW220_RS00355 WP_248054905.1 60993..62174(+) (cinA) [Streptococcus iners subsp. hyiners strain 29892]
ATGAAAGCAGAACTCATCGCCGTAGGCACTGAAATTTTGACCGGTCAGATTGTCAATACCAACGCGCAATTTCTATCTGA
AAAATGTGCTGAATTGGGTATTGACGTCTATTTTCATACAGCAGTAGGCGATAATGAAAAGCGTCTTTTGTCTGTACTGG
AGGTAGCCAGCAAGCGTAGTGAGCTAGTTATTCTCTGTGGAGGACTGGGGCCAACAGAAGATGACTTGACTAAGCAGACC
TTGGCAGCCTTCTTAGGTAGAAAATTGGTCTTTGATGAAAAAGCCATGGCAAAATTAGACCGCTTCTTTGCCAGCCGACC
AGGTCGTGTCCGCACGCCCAACAATGAGCGCCAAGCACAAATCGTTGAGGGAAGTCAGGCTTTGCAAAATCCAGCTGGTT
TGGCAGTAGGAGGCTTGATCGAGCAAGCTGGAGTGACCTATGTTGTCTTACCTGGTCCTCCAAGTGAACTTAGAGCCATG
TTTACAGAAAGTTTACAACCTTTGCTTAACCAGTCAAGTCAGCAACTCTATTCTCGTGTTCTACGCTTTTTTGGTATTGG
CGAAAGTCAGTTGGTGACGATTTTAGCTGATTTGATTGACAAACAAACTGACCCAACTCTTGCCCCCTATGCCAAGGTTG
GTGAAGTGACCTTGCGCTTGTCCACCAAGGCAAACAGTCAAGAAGAAGCCGATTTCCGTCTGAAACAGTTGGAAGAAGAC
ATCTTACAACGTGATAAACTGAGAGAATATTTCTATGCTTACGGTGAGGAAAATAGTCTAGTACAGACAGTAGCAGAGCG
ATTGGTGGAAAAGAATAAAAGCATAGCCATCGTCGAACAGGGAACAGGCGGACTTTTACAGTCAGAAGTCAGTTTGGCTT
TGACTGGGCAACCTTATTTTAGCGGTGGTCAAGTCATCGGTCAGTTAGGTACAGAATCGGGTAGGTGCTCAGAAGAAGCT
GATGGCATTCGTGAGGAGCTACAGGCTGATTTGGGACTGGCTGTGTCGGTACTTATCAAGTCTGAGTCGACAGAGGATAA
CGTTCTTGCAAAGGTATATATAGCCTTGGCTAGCACCTCTGGCATTTCCCAAAAAGAGGTTGACTTGGGTGGCTACTCCT
GGCAACACATCCGCCAATTAGCTTGCTTGCAAGCCTTAGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(308-393)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

86.514

100

0.865
  cinA Streptococcus mitis SK321

56.971

100

0.603
  cinA Streptococcus pneumoniae TIGR4

56.731

100

0.601
  cinA Streptococcus mitis NCTC 12261

56.731

100

0.601
  cinA Streptococcus pneumoniae Rx1

56.731

100

0.601
  cinA Streptococcus pneumoniae R6

56.731

100

0.601
  cinA Streptococcus pneumoniae D39

56.49

100

0.598
  cinA Streptococcus mutans UA159

55.961

100

0.585
  cinA Bacillus subtilis subsp. subtilis str. 168

41.176

99.491

0.41