Detailed information    

insolico Bioinformatically predicted

Overview


Name   dprA   Type   Machinery gene
Locus tag   KM388_RS28745 Genome accession   NZ_CP076216
Coordinates   3643250..3643540 (-) Length   96 a.a.
NCBI ID   WP_324254321.1    Uniprot ID   -
Organism   Bacillus anthracis strain SA020     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3601530..3675455 3643250..3643540 within 0


Gene organization within MGE regions


Location: 3601530..3675455
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KM388_RS18700 (KM388_18690) - 3601873..3603543 (-) 1671 WP_000823085.1 ribonuclease J -
  KM388_RS18705 (KM388_18695) dapA 3604309..3605187 (-) 879 WP_000564767.1 4-hydroxy-tetrahydrodipicolinate synthase -
  KM388_RS18710 (KM388_18700) dapG 3605199..3606431 (-) 1233 WP_000692470.1 aspartate kinase -
  KM388_RS18715 (KM388_18705) asd 3606455..3607501 (-) 1047 WP_000414849.1 aspartate-semialdehyde dehydrogenase -
  KM388_RS18720 (KM388_18710) dpaB 3607652..3608251 (-) 600 WP_001049484.1 dipicolinate synthase subunit B -
  KM388_RS18725 (KM388_18715) dpaA 3608248..3609150 (-) 903 WP_000954726.1 dipicolinic acid synthetase subunit A -
  KM388_RS18730 (KM388_18720) - 3609425..3609676 (-) 252 WP_001239752.1 YlmC/YmxH family sporulation protein -
  KM388_RS18735 (KM388_18725) - 3609803..3611044 (-) 1242 WP_000592993.1 pitrilysin family protein -
  KM388_RS18740 (KM388_18730) - 3611131..3612030 (-) 900 WP_000647529.1 polysaccharide deacetylase family protein -
  KM388_RS18745 (KM388_18735) pnp 3612182..3614320 (-) 2139 WP_000076750.1 polyribonucleotide nucleotidyltransferase -
  KM388_RS18750 (KM388_18740) rpsO 3614481..3614750 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  KM388_RS18755 (KM388_18745) ribF 3614851..3615822 (-) 972 WP_000766711.1 bifunctional riboflavin kinase/FAD synthetase -
  KM388_RS18760 (KM388_18750) truB 3615866..3616789 (-) 924 WP_000399357.1 tRNA pseudouridine(55) synthase TruB -
  KM388_RS18765 (KM388_18755) rbfA 3616876..3617232 (-) 357 WP_000776441.1 30S ribosome-binding factor RbfA -
  KM388_RS18770 (KM388_18760) - 3617248..3617529 (-) 282 WP_000582364.1 DUF503 family protein -
  KM388_RS18775 (KM388_18765) infB 3617526..3619586 (-) 2061 WP_000036340.1 translation initiation factor IF-2 -
  KM388_RS18780 (KM388_18770) - 3619591..3619902 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  KM388_RS18785 (KM388_18775) - 3619903..3620175 (-) 273 WP_000071128.1 YlxR family protein -
  KM388_RS18790 (KM388_18780) nusA 3620187..3621293 (-) 1107 WP_000102606.1 transcription termination factor NusA -
  KM388_RS18795 (KM388_18785) rimP 3621311..3621781 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  KM388_RS18800 (KM388_18790) - 3622114..3626415 (-) 4302 WP_000059983.1 PolC-type DNA polymerase III -
  KM388_RS18805 (KM388_18795) - 3626540..3628240 (-) 1701 WP_000814312.1 proline--tRNA ligase -
  KM388_RS18810 (KM388_18800) rseP 3628350..3629606 (-) 1257 WP_001090228.1 RIP metalloprotease RseP -
  KM388_RS18815 (KM388_18805) dxr 3629623..3630765 (-) 1143 WP_000790359.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  KM388_RS18820 (KM388_18810) cdsA 3630789..3631580 (-) 792 WP_000813581.1 phosphatidate cytidylyltransferase -
  KM388_RS18825 (KM388_18815) uppS 3631598..3632374 (-) 777 WP_000971301.1 isoprenyl transferase -
  KM388_RS18830 (KM388_18820) frr 3632460..3633017 (-) 558 WP_000531503.1 ribosome recycling factor -
  KM388_RS18835 (KM388_18825) pyrH 3633020..3633742 (-) 723 WP_000042663.1 UMP kinase -
  KM388_RS18840 (KM388_18830) tsf 3633809..3634696 (-) 888 WP_001018581.1 translation elongation factor Ts -
  KM388_RS18845 (KM388_18835) rpsB 3634800..3635501 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  KM388_RS18850 (KM388_18840) codY 3635851..3636630 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  KM388_RS18855 (KM388_18845) hslU 3636708..3638099 (-) 1392 WP_000550088.1 ATP-dependent protease ATPase subunit HslU -
  KM388_RS18860 (KM388_18850) hslV 3638122..3638664 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  KM388_RS18865 (KM388_18855) xerC 3638707..3639606 (-) 900 WP_001101226.1 tyrosine recombinase XerC -
  KM388_RS18870 (KM388_18860) trmFO 3639672..3640976 (-) 1305 WP_001991958.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  KM388_RS18875 (KM388_18865) topA 3641027..3643105 (-) 2079 WP_001286969.1 type I DNA topoisomerase -
  KM388_RS28745 dprA 3643250..3643540 (-) 291 WP_324254321.1 DNA-processing protein DprA Machinery gene
  KM388_RS28750 - 3643453..3643653 (-) 201 WP_264371026.1 DNA-protecting protein DprA -
  KM388_RS28755 - 3643643..3644119 (-) 477 WP_264371027.1 DNA-protecting protein DprA -
  KM388_RS18885 (KM388_18875) sucD 3644207..3645109 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  KM388_RS18890 (KM388_18880) sucC 3645130..3646290 (-) 1161 WP_001020786.1 ADP-forming succinate--CoA ligase subunit beta -
  KM388_RS18895 (KM388_18885) rnhB 3646484..3647257 (-) 774 WP_001174713.1 ribonuclease HII -
  KM388_RS18900 (KM388_18890) ylqF 3647309..3648199 (-) 891 WP_000236707.1 ribosome biogenesis GTPase YlqF -
  KM388_RS18905 (KM388_18895) lepB 3648220..3648771 (-) 552 WP_000711857.1 signal peptidase I -
  KM388_RS18910 (KM388_18900) rplS 3648873..3649217 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  KM388_RS18915 (KM388_18905) trmD 3649364..3650098 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  KM388_RS18920 (KM388_18910) rimM 3650098..3650613 (-) 516 WP_000170269.1 ribosome maturation factor RimM -
  KM388_RS18925 (KM388_18915) - 3650734..3650961 (-) 228 WP_000737398.1 KH domain-containing protein -
  KM388_RS18930 (KM388_18920) rpsP 3650976..3651248 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  KM388_RS18935 (KM388_18925) ffh 3651349..3652698 (-) 1350 WP_000863456.1 signal recognition particle protein -
  KM388_RS18940 (KM388_18930) - 3652711..3653043 (-) 333 WP_000891062.1 putative DNA-binding protein -
  KM388_RS18945 (KM388_18935) ftsY 3653177..3654166 (-) 990 WP_000007650.1 signal recognition particle-docking protein FtsY -
  KM388_RS18950 (KM388_18940) smc 3654182..3657751 (-) 3570 WP_000478986.1 chromosome segregation protein SMC -
  KM388_RS18955 (KM388_18945) rncS 3657898..3658635 (-) 738 WP_001146873.1 ribonuclease III -
  KM388_RS18960 (KM388_18950) acpP 3658694..3658927 (-) 234 WP_000786062.1 acyl carrier protein -
  KM388_RS18965 (KM388_18955) fabG 3658997..3659737 (-) 741 WP_000911782.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  KM388_RS18970 (KM388_18960) fabD 3659737..3660681 (-) 945 WP_000516948.1 ACP S-malonyltransferase -
  KM388_RS18975 (KM388_18965) plsX 3660696..3661688 (-) 993 WP_000684111.1 phosphate acyltransferase PlsX -
  KM388_RS18980 (KM388_18970) fapR 3661685..3662278 (-) 594 WP_000747352.1 transcription factor FapR -
  KM388_RS18985 (KM388_18975) recG 3662367..3664415 (-) 2049 WP_001006884.1 ATP-dependent DNA helicase RecG -
  KM388_RS18990 (KM388_18980) - 3664705..3666381 (-) 1677 WP_000027136.1 DAK2 domain-containing protein -
  KM388_RS18995 (KM388_18985) - 3666404..3666766 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  KM388_RS19000 (KM388_18990) rpmB 3667145..3667333 (+) 189 WP_000124778.1 50S ribosomal protein L28 -
  KM388_RS19005 (KM388_18995) spoVM 3667407..3667487 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  KM388_RS19010 (KM388_19000) - 3667554..3668234 (-) 681 WP_025388434.1 thiamine diphosphokinase -
  KM388_RS19015 (KM388_19005) rpe 3668334..3668978 (-) 645 WP_000589969.1 ribulose-phosphate 3-epimerase -
  KM388_RS19020 (KM388_19010) rsgA 3668981..3669862 (-) 882 WP_001113935.1 ribosome small subunit-dependent GTPase A -
  KM388_RS19025 (KM388_19015) prkC 3670131..3672104 (-) 1974 WP_000904759.1 serine/threonine protein kinase PrkC -
  KM388_RS19030 (KM388_19020) - 3672113..3672865 (-) 753 WP_000648699.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  KM388_RS19035 (KM388_19025) rlmN 3672870..3673958 (-) 1089 WP_000450543.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  KM388_RS19040 (KM388_19030) rsmB 3673963..3675297 (-) 1335 WP_001249680.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence


Protein


Download         Length: 96 a.a.        Molecular weight: 10600.29 Da        Isoelectric Point: 9.7220

>NTDB_id=573688 KM388_RS28745 WP_324254321.1 3643250..3643540(-) (dprA) [Bacillus anthracis strain SA020]
MYIVINRVSSALCTKKWYFPKRNRIISGISKGVLVVEAKSRSGTLITADLALEQNREVFALPGPIFTDSASGTNHLIQQG
AKLVRNAEDILEEILN

Nucleotide


Download         Length: 291 bp        

>NTDB_id=573688 KM388_RS28745 WP_324254321.1 3643250..3643540(-) (dprA) [Bacillus anthracis strain SA020]
ATATATATTGTTATTAACAGAGTATCCTCCGCACTATGCACCAAAAAATGGTATTTTCCAAAAAGGAATCGAATTATTAG
TGGTATAAGTAAAGGTGTTTTAGTTGTAGAAGCGAAATCGAGAAGCGGAACACTTATTACTGCAGACCTTGCTCTAGAGC
AAAATAGAGAGGTATTTGCACTTCCTGGACCTATATTTACAGATAGTGCATCAGGAACAAATCATCTTATTCAACAAGGA
GCGAAACTAGTAAGAAATGCAGAAGATATACTAGAAGAGATTTTAAATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Bacillus subtilis subsp. subtilis str. 168

54.839

96.875

0.531

  dprA Lactococcus lactis subsp. cremoris KW2

63.75

83.333

0.531

  dprA Haemophilus influenzae Rd KW20

65.789

79.167

0.521

  dprA Vibrio campbellii strain DS40M4

65.789

79.167

0.521

  dprA Staphylococcus aureus MW2

52.747

94.792

0.5

  dprA Staphylococcus aureus N315

52.747

94.792

0.5

  dprA Glaesserella parasuis strain SC1401

60.526

79.167

0.479

  dprA Vibrio cholerae strain A1552

56.962

82.292

0.469

  dprA Legionella pneumophila strain ERS1305867

57.143

80.208

0.458

  dprA/cilB/dalA Streptococcus mitis NCTC 12261

54.43

82.292

0.448

  dprA/cilB/dalA Streptococcus mitis SK321

54.43

82.292

0.448

  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

54.43

82.292

0.448

  dprA/cilB/dalA Streptococcus pneumoniae R6

54.43

82.292

0.448

  dprA/cilB/dalA Streptococcus pneumoniae D39

54.43

82.292

0.448

  dprA/cilB/dalA Streptococcus pneumoniae Rx1

54.43

82.292

0.448

  dprA Streptococcus mutans UA159

53.165

82.292

0.438

  dprA Acinetobacter baylyi ADP1

53.247

80.208

0.427

  dprA Acinetobacter baumannii D1279779

51.948

80.208

0.417

  dprA Acinetobacter baumannii strain A118

51.948

80.208

0.417

  dprA Neisseria meningitidis MC58

53.333

78.125

0.417

  dprA Neisseria meningitidis strain C311

53.333

78.125

0.417

  dprA Neisseria gonorrhoeae strain FA1090

52

78.125

0.406

  dprA Neisseria gonorrhoeae MS11

52

78.125

0.406

  dprA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

50.649

80.208

0.406

  dprA Thermus thermophilus HB27

50.649

80.208

0.406