Detailed information NTG1128011

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: FGL23_RS10555
• Genome accession: NZ_LR594049
• Coordinates: 2167581..2168063 (-)
• Length: 160 a.a.
• NCBI ID: WP_061604085.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain NCTC10231
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	2159861..2183136	2167581..2168063	within	0

Gene organization within MGE regions

Location: 2159861..2183136

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL23_RS10445 (NCTC10231_02092)	mreC	2159861..2160676 (-)	816	WP_061602341.1	rod shape-determining protein MreC	-
FGL23_RS10555 (NCTC10231_02114)	comR/comR2	2167581..2168063 (-)	483	WP_061604085.1	sigma-70 family RNA polymerase sigma factor	Regulator
FGL23_RS10570 (NCTC10231_02117)	ftsH	2168588..2170570 (-)	1983	WP_061603315.1	ATP-dependent zinc metalloprotease FtsH	-
FGL23_RS10575 (NCTC10231_02118)	hpt	2170589..2171131 (-)	543	WP_045504966.1	hypoxanthine phosphoribosyltransferase	-
FGL23_RS10580 (NCTC10231_02119)	tilS	2171136..2172413 (-)	1278	WP_061603314.1	tRNA lysidine(34) synthetase TilS	-
FGL23_RS10585 (NCTC10231_02120)	-	2172410..2173690 (-)	1281	WP_061603313.1	serine hydrolase	-
FGL23_RS10590	-	2173690..2173806 (-)	117	WP_012131072.1	SP_0009 family protein	-
FGL23_RS10595 (NCTC10231_02121)	-	2173809..2174177 (-)	369	WP_012131073.1	FtsB family cell division protein	-
FGL23_RS10600 (NCTC10231_02122)	-	2174170..2174436 (-)	267	WP_061603312.1	RNA-binding S4 domain-containing protein	-
FGL23_RS10605 (NCTC10231_02123)	mfd	2174502..2178005 (-)	3504	WP_138115477.1	transcription-repair coupling factor	-
FGL23_RS10610 (NCTC10231_02124)	pth	2177998..2178567 (-)	570	WP_061603311.1	aminoacyl-tRNA hydrolase	-
FGL23_RS10615 (NCTC10231_02125)	ychF	2178641..2179756 (-)	1116	WP_008808030.1	redox-regulated ATPase YchF	-
FGL23_RS10630 (NCTC10231_02128)	comE/comE2	2180078..2180845 (-)	768	WP_008808031.1	competence system response regulator transcription factor ComE	Regulator
FGL23_RS10635 (NCTC10231_02129)	comD/comD1	2180842..2182203 (-)	1362	WP_061603310.1	competence system sensor histidine kinase ComD	Regulator
FGL23_RS10640 (NCTC10231_02130)	comC/comC1	2182219..2182371 (-)	153	WP_012131079.1	bacteriocin	Regulator
FGL23_RS10650 (NCTC10231_02132)	rlmH	2182657..2183136 (-)	480	WP_061603309.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-

Sequence

Protein

• Length: 160 a.a.
• Molecular weight: 19966.95 Da
• Isoelectric Point: 9.3213

>NTDB_id=1128011 FGL23_RS10555 WP_061604085.1 2167581..2168063(-) (comR/comR2) [Streptococcus gordonii strain NCTC10231]
MKFEEVYKQVEGIVRRCYKDYYLHLWEYADWRQEGMMVLYELIKSHPNLLEDHPRLYRYFKTKFRNRIHDLIRRQESQKR
KLDRQPYEEVSEIGHCLRMKELYLDELVAFRSAMSEYRSRLSPEEAKQYERLMADERFKGRKAMLKDLSYHLRDFNPRLD

Nucleotide

• Length: 483 bp

>NTDB_id=1128011 FGL23_RS10555 WP_061604085.1 2167581..2168063(-) (comR/comR2) [Streptococcus gordonii strain NCTC10231]
ATGAAATTTGAGGAGGTATACAAACAAGTTGAAGGGATAGTCAGGCGATGTTATAAAGATTATTATCTGCACTTATGGGA
GTATGCAGATTGGAGGCAGGAAGGGATGATGGTTTTGTACGAATTGATAAAAAGCCATCCTAATCTACTGGAAGATCATC
CACGTCTGTACCGTTACTTCAAGACCAAGTTTCGGAACAGAATACATGATTTGATTCGCCGACAAGAGAGTCAAAAACGC
AAATTGGACAGGCAACCCTATGAAGAGGTCAGCGAGATAGGCCATTGTTTAAGAATGAAGGAGCTTTATCTAGATGAACT
GGTAGCCTTTAGAAGTGCCATGTCAGAGTATAGAAGCCGTCTCAGCCCAGAAGAGGCAAAACAATACGAGAGGTTGATGG
CAGATGAAAGATTCAAAGGACGTAAGGCAATGCTCAAAGATCTGTCCTATCACTTAAGGGATTTCAATCCTCGTTTAGAT
TAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	96.25	100	0.963
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	96.25	100	0.963
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	50.641	97.5	0.494
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	50	97.5	0.488
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	50	97.5	0.488
comX/comX1	Streptococcus pneumoniae TIGR4	48.718	97.5	0.475
comX/comX2	Streptococcus pneumoniae Rx1	48.718	97.5	0.475
comX/comX1	Streptococcus pneumoniae Rx1	48.718	97.5	0.475
comX/comX2	Streptococcus pneumoniae D39	48.718	97.5	0.475
comX/comX1	Streptococcus pneumoniae D39	48.718	97.5	0.475
comX/comX2	Streptococcus pneumoniae R6	48.718	97.5	0.475
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	48.718	97.5	0.475
comX/comX1	Streptococcus pneumoniae R6	48.718	97.5	0.475
comX/comX2	Streptococcus pneumoniae TIGR4	48.718	97.5	0.475
comX/sigX	Streptococcus suis isolate S10	48.387	96.875	0.469
comX/sigX	Streptococcus suis P1/7	48.387	96.875	0.469
comX/sigX	Streptococcus suis D9	48.387	96.875	0.469
comX/sigX	Streptococcus mutans UA159	46.795	97.5	0.456
comX	Streptococcus salivarius SK126	43.871	96.875	0.425
comX/sigX	Streptococcus salivarius strain HSISS4	43.871	96.875	0.425
comX	Streptococcus thermophilus LMG 18311	43.226	96.875	0.419
comX	Streptococcus thermophilus LMD-9	43.226	96.875	0.419
comX	Streptococcus sobrinus strain NIDR 6715-7	41.558	96.25	0.4
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.873	98.75	0.394
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	40.26	96.25	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	40.26	96.25	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	39.61	96.25	0.381
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	39.61	96.25	0.381
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	39.61	96.25	0.381
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	39.61	96.25	0.381