Detailed information
Overview
| Name | comC/comC1 | Type | Regulator |
| Locus tag | FGL23_RS10640 | Genome accession | NZ_LR594049 |
| Coordinates | 2182219..2182371 (-) | Length | 50 a.a. |
| NCBI ID | WP_012131079.1 | Uniprot ID | - |
| Organism | Streptococcus gordonii strain NCTC10231 | ||
| Function | binding to ComD; induce autophosphorylation of ComD (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 2159861..2183136 | 2182219..2182371 | within | 0 |
Gene organization within MGE regions
Location: 2159861..2183136
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FGL23_RS10445 (NCTC10231_02092) | mreC | 2159861..2160676 (-) | 816 | WP_061602341.1 | rod shape-determining protein MreC | - |
| FGL23_RS10555 (NCTC10231_02114) | comR/comR2 | 2167581..2168063 (-) | 483 | WP_061604085.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| FGL23_RS10570 (NCTC10231_02117) | ftsH | 2168588..2170570 (-) | 1983 | WP_061603315.1 | ATP-dependent zinc metalloprotease FtsH | - |
| FGL23_RS10575 (NCTC10231_02118) | hpt | 2170589..2171131 (-) | 543 | WP_045504966.1 | hypoxanthine phosphoribosyltransferase | - |
| FGL23_RS10580 (NCTC10231_02119) | tilS | 2171136..2172413 (-) | 1278 | WP_061603314.1 | tRNA lysidine(34) synthetase TilS | - |
| FGL23_RS10585 (NCTC10231_02120) | - | 2172410..2173690 (-) | 1281 | WP_061603313.1 | serine hydrolase | - |
| FGL23_RS10590 | - | 2173690..2173806 (-) | 117 | WP_012131072.1 | SP_0009 family protein | - |
| FGL23_RS10595 (NCTC10231_02121) | - | 2173809..2174177 (-) | 369 | WP_012131073.1 | FtsB family cell division protein | - |
| FGL23_RS10600 (NCTC10231_02122) | - | 2174170..2174436 (-) | 267 | WP_061603312.1 | RNA-binding S4 domain-containing protein | - |
| FGL23_RS10605 (NCTC10231_02123) | mfd | 2174502..2178005 (-) | 3504 | WP_138115477.1 | transcription-repair coupling factor | - |
| FGL23_RS10610 (NCTC10231_02124) | pth | 2177998..2178567 (-) | 570 | WP_061603311.1 | aminoacyl-tRNA hydrolase | - |
| FGL23_RS10615 (NCTC10231_02125) | ychF | 2178641..2179756 (-) | 1116 | WP_008808030.1 | redox-regulated ATPase YchF | - |
| FGL23_RS10630 (NCTC10231_02128) | comE/comE2 | 2180078..2180845 (-) | 768 | WP_008808031.1 | competence system response regulator transcription factor ComE | Regulator |
| FGL23_RS10635 (NCTC10231_02129) | comD/comD1 | 2180842..2182203 (-) | 1362 | WP_061603310.1 | competence system sensor histidine kinase ComD | Regulator |
| FGL23_RS10640 (NCTC10231_02130) | comC/comC1 | 2182219..2182371 (-) | 153 | WP_012131079.1 | bacteriocin | Regulator |
| FGL23_RS10650 (NCTC10231_02132) | rlmH | 2182657..2183136 (-) | 480 | WP_061603309.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
Sequence
Protein
Download Length: 50 a.a. Molecular weight: 6146.21 Da Isoelectric Point: 10.8831
>NTDB_id=1128014 FGL23_RS10640 WP_012131079.1 2182219..2182371(-) (comC/comC1) [Streptococcus gordonii strain NCTC10231]
MKKKNKQNLLPKELQQFEILTERKLEQVTGGDVRSNKIRLWWENIFFNKK
MKKKNKQNLLPKELQQFEILTERKLEQVTGGDVRSNKIRLWWENIFFNKK
Nucleotide
Download Length: 153 bp
>NTDB_id=1128014 FGL23_RS10640 WP_012131079.1 2182219..2182371(-) (comC/comC1) [Streptococcus gordonii strain NCTC10231]
ATGAAAAAGAAAAACAAACAAAATCTATTGCCAAAAGAGTTACAACAATTTGAAATTTTGACAGAAAGAAAATTAGAGCA
AGTTACTGGTGGAGATGTTCGCTCAAACAAAATTAGATTATGGTGGGAAAATATATTCTTTAATAAAAAATAA
ATGAAAAAGAAAAACAAACAAAATCTATTGCCAAAAGAGTTACAACAATTTGAAATTTTGACAGAAAGAAAATTAGAGCA
AGTTACTGGTGGAGATGTTCGCTCAAACAAAATTAGATTATGGTGGGAAAATATATTCTTTAATAAAAAATAA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comC/comC1 | Streptococcus gordonii str. Challis substr. CH1 |
100 |
100 |
1 |
| comC/comC2 | Streptococcus gordonii strain NCTC7865 |
74 |
100 |
0.74 |