Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS17508  |
| T6SS type | Type i3 |
| Strain | Burkholderia glumae BGR1 |
| Replicon (RefSeq) | chromosome II (NC_012721) |
| Location | 154526..188085 |
| Function | - |
| Comment | T6SS group_2 was not clustered with the bacterial and eukaryotic cell targeting systems despite the presence of a complete T6SS gene cluster. |
| References | [1] Kim N, Kim JJ, Kim I, Mannaa M, Park J, Kim J, Lee HH, Lee SB, Park DS, Sul WJ, Seo YS. et al (2020) Type VI secretion systems of plant-pathogenic Burkholderia glumae BGR1 play a functionally distinct role in interspecies interactions and virulence.. Mol Plant Pathol. 21(8):1055-1069. [PudMed:32643866] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| BGLU_RS18620 | 149529..150077 | + | 549 | WP_012733021.1 | type 1 fimbrial protein | ||
| BGLU_RS18625 | 150173..150952 | + | 780 | WP_012733022.1 | fimbria/pilus periplasmic chaperone | ||
| BGLU_RS18630 | 151021..153837 | + | 2817 | WP_012733023.1 | fimbrial biogenesis outer membrane usher protein | ||
| BGLU_RS18635 | 153938..154474 | + | 537 | WP_012733024.1 | type 1 fimbrial protein | ||
| BGLU_RS18640 | 154493..155251 | + | 759 | WP_012733025.1 | DotU family type IV/VI secretion system protein | ||
| BGLU_RS18645 | 155248..156957 | + | 1710 | WP_012733026.1 | OmpA family protein | ||
| T6CP259603 | TssB | BGLU_RS18650 (tssB) | 157164..157697 | + | 534 | WP_012733027.1 | type VI secretion system contractile sheath small subunit |
| T6CP259604 | TssC | BGLU_RS18655 (tssC) | 157775..159277 | + | 1503 | WP_012733028.1 | type VI secretion system contractile sheath large subunit |
| T6CP259605 | TssD | BGLU_RS18660 | 159409..159891 | + | 483 | WP_012733029.1 | type VI secretion system tube protein Hcp |
| BGLU_RS18665 (tssJ) | 160040..160594 | + | 555 | WP_012733030.1 | type VI secretion system lipoprotein TssJ | ||
| T6CP259607 | TssK | BGLU_RS18670 (tssK) | 160591..161940 | + | 1350 | WP_012733031.1 | type VI secretion system baseplate subunit TssK |
| T6CP259608 | TssL | BGLU_RS18675 (tssL) | 161937..163253 | + | 1317 | WP_012733032.1 | type VI secretion system protein TssL, long form |
| T6CP259609 | TssM | BGLU_RS18680 (tssM) | 163266..167363 | + | 4098 | WP_012733033.1 | type VI secretion system membrane subunit TssM |
| BGLU_RS18685 (tssI) | 167429..169432 | + | 2004 | pseudogene | type VI secretion system tip protein VgrG | ||
| T6CP259611 | TssI | BGLU_RS18690 (tssI) | 169581..172157 | + | 2577 | WP_043308110.1 | type VI secretion system tip protein VgrG |
| BGLU_RS32620 | 172236..172499 | + | 264 | WP_012733036.1 | PAAR domain-containing protein | ||
| BGLU_RS18695 | 172557..175994 | + | 3438 | WP_148271062.1 | RHS repeat protein | ||
| BGLU_RS18700 | 175899..177299 | - | 1401 | WP_012733038.1 | hypothetical protein | ||
| BGLU_RS18705 | 177345..178352 | - | 1008 | WP_012733039.1 | fimbrial protein | ||
| T6CP259612 | TssA | BGLU_RS18710 | 178418..179482 | - | 1065 | WP_012733040.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| T6CP259613 | TssG | BGLU_RS18715 (tssG) | 179501..180571 | - | 1071 | WP_012733041.1 | type VI secretion system baseplate subunit TssG |
| T6CP259614 | TssF | BGLU_RS18720 (tssF) | 180568..182448 | - | 1881 | WP_012733042.1 | type VI secretion system baseplate subunit TssF |
| T6CP259615 | TssE | BGLU_RS18725 (tssE) | 182450..182968 | - | 519 | WP_012733043.1 | type VI secretion system baseplate subunit TssE |
| BGLU_RS18730 | 182965..183798 | - | 834 | WP_012733044.1 | virulence protein SciE type | ||
| BGLU_RS31530 | 183782..184969 | - | 1188 | WP_012733045.1 | TagK domain-containing protein | ||
| T6CP259616 | TssH | BGLU_RS18740 (tssH) | 185284..188085 | + | 2802 | WP_012733046.1 | type VI secretion system ATPase TssH |
| BGLU_RS18745 | 188140..188403 | + | 264 | WP_017432145.1 | hypothetical protein | ||
| BGLU_RS18750 | 188400..190721 | + | 2322 | WP_012733047.1 | response regulator | ||
| BGLU_RS32625 | 190989..191405 | - | 417 | WP_157384073.1 | response regulator | ||
| BGLU_RS35805 | 191664..192194 | - | 531 | WP_173941228.1 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF76652 |
BGLU_RS18660 | - | - | Burkholderia glumae BGR1 | chromosome (NC_012721) | 159409..159891 (+) | WP_012733029.1 |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|