Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01220  |
| T6SS type | Type i1 |
| Strain | Campylobacter jejuni strain WP2202 |
| Replicon (GenBank) | plasmid pCJDM202 (CP014743) |
| Location | 13397..30371 |
| Function | anti-eukaryotic |
| Comment | When compared to the wild-type WP2-202, the Δhcp3 mutant showed a significant decrease in survival and urvival of the wild-type WP2-202 was significantly higher (P < 0.05) than Δhcp3 at 24, 48 and 72 h |
| References | [1] Marasini D, Karki AB, Bryant JM, Sheaff RJ, Fakhr MK. et al (2020) Molecular characterization of megaplasmids encoding the type VI secretion system in Campylobacter jejuni isolated from chicken livers and gizzards.. Sci Rep. 10(1):12514. [PudMed:32719325] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TagH | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| A0W69_08955 | 9123..9992 | - | 870 | 1004801949 | hypothetical protein | ||
| A0W69_08960 | 10038..11051 | - | 1014 | 1004801950 | hypothetical protein | ||
| A0W69_08965 | 11054..12130 | - | 1077 | 1004801951 | hypothetical protein | ||
| A0W69_08970 | 12120..12464 | - | 345 | 1004801952 | hypothetical protein | ||
| A0W69_08975 | 12556..12858 | - | 303 | 1004802042 | hypothetical protein | ||
| T6CP015426 | TssI | A0W69_08980 | 13397..15898 | - | 2502 | 1004801953 | type VI secretion protein VgrG |
| T6CP015427 | TssG | A0W69_08985 | 16048..16956 | - | 909 | 1004801954 | type VI secretion protein |
| T6CP015428 | TssF | A0W69_08990 | 16953..18674 | - | 1722 | 1004801955 | type VI secretion protein |
| T6CP015429 | TssE | A0W69_08995 | 18671..19063 | - | 393 | 1004801956 | hypothetical protein |
| T6CP015430 | TssC | A0W69_09000 | 19066..20520 | - | 1455 | 1004801957 | type VI secretion protein |
| T6CP015431 | TssB | A0W69_09005 | 20522..21007 | - | 486 | 1004801958 | type VI secretion protein |
| T6CP015432 | TssA | A0W69_09010 | 21076..22311 | - | 1236 | 1004801959 | nucleobase:cation symporter |
| T6CP015433 | TssJ | A0W69_09015 | 22437..22883 | + | 447 | 1004801960 | type VI secretion protein |
| T6CP015434 | TssK | A0W69_09020 | 22893..24290 | + | 1398 | 1004801961 | type VI secretion protein |
| T6CP015435 | TssL | A0W69_09025 | 24287..25060 | + | 774 | 1004801962 | glutamyl-tRNA amidotransferase |
| T6CP015436 | TssD | A0W69_09030 | 25315..25830 | - | 516 | 1004801963 | hypothetical protein |
| T6CP015437 | TssM | A0W69_09035 | 25948..29475 | + | 3528 | 1004801964 | hypothetical protein |
| T6CP015438 | TagH | A0W69_09040 | 29472..30371 | + | 900 | 1004801965 | hypothetical protein |
| A0W69_09045 | 30389..31615 | - | 1227 | pseudogene | hypothetical protein | ||
| A0W69_09050 | 31626..35048 | - | 3423 | 1004801966 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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