Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00343  |
| T6SS type | Type i4b |
| Strain | Burkholderia glumae BGR1 |
| Replicon (RefSeq) | chromosome I (NC_012724) |
| Location | 397352..417437 |
| Function | anti-bacterial |
| Comment | T6SS group_1 is involved in bacterial competition by exerting antibacterial effects. |
| References | [1] Kim N, Kim JJ, Kim I, Mannaa M, Park J, Kim J, Lee HH, Lee SB, Park DS, Sul WJ, Seo YS. et al (2020) Type VI secretion systems of plant-pathogenic Burkholderia glumae BGR1 play a functionally distinct role in interspecies interactions and virulence.. Mol Plant Pathol. 21(8):1055-1069. [PudMed:32643866] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| BGLU_RS01905 | 392670..392993 | + | 324 | WP_148270980.1 | hypothetical protein | ||
| BGLU_RS31925 | 393288..393494 | + | 207 | WP_043307029.1 | AlpA family phage regulatory protein | ||
| BGLU_RS31930 | 394201..394374 | + | 174 | WP_080569283.1 | DUF3380 domain-containing protein | ||
| BGLU_RS35290 | 394383..394559 | + | 177 | WP_017432168.1 | DUF3380 domain-containing protein | ||
| BGLU_RS31310 | 394556..395188 | + | 633 | WP_050811391.1 | hypothetical protein | ||
| BGLU_RS01920 | 395986..397173 | + | 1188 | WP_012734474.1 | GGDEF domain-containing protein | ||
| T6CP003485 | TssL | BGLU_RS01925 (icmH) | 397352..398143 | - | 792 | WP_012734475.1 | type IVB secretion system protein IcmH/DotU |
| T6CP003486 | TssK | BGLU_RS01930 (tssK) | 398140..399486 | - | 1347 | WP_012734476.1 | type VI secretion system baseplate subunit TssK |
| T6CP003487 | TssJ | BGLU_RS01935 (tssJ) | 399588..400205 | - | 618 | WP_012734477.1 | type VI secretion system lipoprotein TssJ |
| BGLU_RS01940 | 400575..401219 | + | 645 | WP_012734478.1 | tetratricopeptide repeat protein | ||
| T6CP003488 | TssB | BGLU_RS01945 (tssB) | 401263..401802 | + | 540 | WP_012734479.1 | type VI secretion system contractile sheath small subunit |
| T6CP003489 | TssC | BGLU_RS01950 (tssC) | 401817..403307 | + | 1491 | WP_012734480.1 | type VI secretion system contractile sheath large subunit |
| T6CP003490 | TssD | BGLU_RS01955 | 403385..403888 | + | 504 | WP_012734481.1 | type VI secretion system tube protein Hcp |
| T6CP003491 | TssE | BGLU_RS01960 (tssE) | 403965..404447 | + | 483 | WP_012734482.1 | type VI secretion system baseplate subunit TssE |
| T6CP003492 | TssF | BGLU_RS01965 (tssF) | 404540..406378 | + | 1839 | WP_012734483.1 | type VI secretion system baseplate subunit TssF |
| T6CP003493 | TssG | BGLU_RS01970 (tssG) | 406342..407439 | + | 1098 | WP_012734484.1 | type VI secretion system baseplate subunit TssG |
| T6CP003494 | TssH | BGLU_RS01975 (tssH) | 407505..410174 | + | 2670 | WP_012734485.1 | type VI secretion system ATPase TssH |
| T6CP003495 | TssA | BGLU_RS01980 (tssA) | 410265..411407 | + | 1143 | WP_012734486.1 | type VI secretion system protein TssA |
| T6CP011752 | TssL | BGLU_RS01985 | 411501..412568 | - | 1068 | WP_012734487.1 | OmpA family protein |
| BGLU_RS01990 (tagF) | 412573..413565 | - | 993 | WP_012734488.1 | type VI secretion system-associated protein TagF | ||
| T6CP003496 | TssM | BGLU_RS01995 (tssM) | 413562..417437 | - | 3876 | WP_012734489.1 | type VI secretion system membrane subunit TssM |
| BGLU_RS02000 | 417703..418554 | - | 852 | WP_012734490.1 | M15 family metallopeptidase | ||
| BGLU_RS02005 | 418678..419637 | + | 960 | WP_012734491.1 | hypothetical protein | ||
| BGLU_RS02010 | 420023..421057 | + | 1035 | WP_026051673.1 | transporter | ||
| BGLU_RS31940 | 421130..421282 | - | 153 | WP_012734493.1 | DUF1427 family protein | ||
| BGLU_RS02015 | 421324..422301 | - | 978 | WP_012734494.1 | zinc-binding alcohol dehydrogenase family protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0359 |
bglu_1g09700 (tepR) | protein | Global regulator | Burkholderia glumae BGR1 | chromosome (NC_012724) | 1045102..1046502 (-) | - | Unknown (↓) |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF00430 |
BGLU_RS01955 | - | - | Burkholderia glumae BGR1 | chromosome (NC_012724) | 403385..403888 (+) | WP_012734481.1 |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|