Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   AAFQ93_RS00875 Genome accession   NZ_CP152419
Coordinates   183558..184022 (-) Length   154 a.a.
NCBI ID   WP_223140124.1    Uniprot ID   -
Organism   Streptococcus nidrosiense strain SO-23-1     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 178558..189022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFQ93_RS00875 (AAFQ93_00875) comX/sigX/comX2/sigX2 183558..184022 (-) 465 WP_223140124.1 sigma-70 family RNA polymerase sigma factor Regulator
  AAFQ93_RS00880 (AAFQ93_00880) - 184426..184752 (-) 327 WP_375555375.1 helix-turn-helix domain-containing protein -
  AAFQ93_RS00885 (AAFQ93_00885) - 184939..185778 (+) 840 WP_375555376.1 excalibur calcium-binding domain-containing protein -
  AAFQ93_RS00890 (AAFQ93_00890) - 185771..186208 (+) 438 WP_375555377.1 thiol-disulfide isomerase -
  AAFQ93_RS00895 (AAFQ93_00895) - 186349..187149 (+) 801 WP_375555378.1 hypothetical protein -
  AAFQ93_RS00900 (AAFQ93_00900) - 187160..187897 (+) 738 WP_375555379.1 hypothetical protein -
  AAFQ93_RS00905 (AAFQ93_00905) - 187904..189004 (+) 1101 WP_375555380.1 DUF6287 domain-containing protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 19119.89 Da        Isoelectric Point: 7.0523

>NTDB_id=989138 AAFQ93_RS00875 WP_223140124.1 183558..184022(-) (comX/sigX/comX2/sigX2) [Streptococcus nidrosiense strain SO-23-1]
MLEKYYAKVKGIVHKCRKDYYLHLWEKEDWDQEGMICLHELLEYHPELVEEEKKLYVYFKTKFRNRILDSVRKQESQKRR
LDRMAYEEVGEISHRLPEGGLWLDDYYALHELLNTYRRKLPEDKQEAYERLWADERFKGRKALLRELKETLQDF

Nucleotide


Download         Length: 465 bp        

>NTDB_id=989138 AAFQ93_RS00875 WP_223140124.1 183558..184022(-) (comX/sigX/comX2/sigX2) [Streptococcus nidrosiense strain SO-23-1]
ATGCTTGAAAAGTATTATGCGAAGGTAAAAGGAATTGTTCATAAATGTAGAAAAGACTACTATCTCCACCTGTGGGAGAA
AGAGGATTGGGACCAAGAAGGCATGATCTGTCTCCATGAACTTCTAGAATATCATCCAGAACTAGTGGAAGAAGAAAAGA
AACTCTACGTCTACTTCAAAACAAAATTTCGCAATCGAATCCTTGATAGCGTTAGAAAACAAGAGAGTCAAAAACGTCGC
CTAGACCGGATGGCCTACGAAGAAGTAGGAGAAATTAGCCATCGTCTACCAGAAGGAGGATTGTGGTTGGATGATTACTA
CGCCCTTCATGAATTGTTGAATACTTATAGAAGAAAATTACCAGAAGATAAACAAGAAGCCTACGAACGCCTCTGGGCAG
ACGAACGATTTAAAGGCCGCAAAGCCCTTCTCAGAGAGCTGAAGGAAACATTACAAGACTTCTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

62.987

100

0.63
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

61.688

100

0.617
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

61.039

100

0.61
  comX/comX2 Streptococcus pneumoniae D39

59.74

100

0.597
  comX/comX1 Streptococcus pneumoniae D39

59.74

100

0.597
  comX/comX2 Streptococcus pneumoniae R6

59.74

100

0.597
  comX/comX1 Streptococcus pneumoniae R6

59.74

100

0.597
  comX/comX2 Streptococcus pneumoniae Rx1

59.74

100

0.597
  comX/comX1 Streptococcus pneumoniae Rx1

59.74

100

0.597
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

59.74

100

0.597
  comX/comX1 Streptococcus pneumoniae TIGR4

59.091

100

0.591
  comX/comX2 Streptococcus pneumoniae TIGR4

59.091

100

0.591
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

57.516

99.351

0.571
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

57.516

99.351

0.571
  comX/sigX Streptococcus mutans UA159

51.634

99.351

0.513
  comX/sigX Streptococcus suis D9

50.327

99.351

0.5
  comX/sigX Streptococcus suis isolate S10

50.327

99.351

0.5
  comX/sigX Streptococcus suis P1/7

50.327

99.351

0.5
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

47.651

96.753

0.461
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

47.651

96.753

0.461
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

47.651

96.753

0.461
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

47.651

96.753

0.461
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

47.651

96.753

0.461
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

47.651

96.753

0.461
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

42.857

100

0.429
  comX/sigX Streptococcus salivarius strain HSISS4

43.624

96.753

0.422
  comX Streptococcus salivarius SK126

43.624

96.753

0.422
  comX Streptococcus sobrinus strain NIDR 6715-7

43.333

97.403

0.422
  comX Streptococcus thermophilus LMG 18311

41.722

98.052

0.409
  comX Streptococcus thermophilus LMD-9

41.722

98.052

0.409

Multiple sequence alignment