Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   WJ054_RS02080 Genome accession   NZ_CP149485
Coordinates   388472..388954 (+) Length   160 a.a.
NCBI ID   WP_406848823.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain STG643     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 383472..393954
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WJ054_RS02080 (WJ054_02080) comX/sigX/comX2/sigX2 388472..388954 (+) 483 WP_406848823.1 competence protein ComX Regulator
  WJ054_RS02085 (WJ054_02085) - 389199..389726 (+) 528 WP_015057333.1 YqeG family HAD IIIA-type phosphatase -
  WJ054_RS02090 (WJ054_02090) yqeH 389726..390844 (+) 1119 WP_002985994.1 ribosome biogenesis GTPase YqeH -
  WJ054_RS02095 (WJ054_02095) yhbY 390870..391178 (+) 309 WP_003059820.1 ribosome assembly RNA-binding protein YhbY -
  WJ054_RS02100 (WJ054_02100) - 391247..391879 (+) 633 WP_002991091.1 nicotinate-nucleotide adenylyltransferase -
  WJ054_RS02105 (WJ054_02105) yqeK 391876..392469 (+) 594 WP_003061317.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  WJ054_RS02110 (WJ054_02110) - 392445..392705 (+) 261 WP_011528257.1 isochorismatase family protein -
  WJ054_RS02115 (WJ054_02115) rsfS 392707..393060 (+) 354 WP_003049699.1 ribosome silencing factor -
  WJ054_RS02120 (WJ054_02120) - 393108..393851 (+) 744 WP_041781493.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 18963.78 Da        Isoelectric Point: 8.3220

>NTDB_id=959365 WJ054_RS02080 WP_406848823.1 388472..388954(+) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae subsp. equisimilis strain STG643]
MSLETGEVFEKVKPIILKLKRHYYLQLWETDDWLQEGHLVLVKLLERHPELVGDEARLYRYFKTKFSSYLKDVLRRQESQ
KRQFDKMAYEEIGDVAHAIPAGGLWLDDYVAYREVLVQVEEALSEADRKQLQALVRGERFKGRQALLRKVRPYFSGFDQG

Nucleotide


Download         Length: 483 bp        

>NTDB_id=959365 WJ054_RS02080 WP_406848823.1 388472..388954(+) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae subsp. equisimilis strain STG643]
ATGTCGTTAGAGACAGGGGAGGTTTTTGAGAAGGTCAAACCTATTATTTTAAAGCTGAAGCGTCATTATTACTTACAGTT
GTGGGAGACGGATGACTGGTTACAAGAGGGGCATTTGGTTTTAGTGAAGTTGTTGGAACGTCACCCAGAGTTAGTAGGAG
ATGAGGCTCGCTTGTATCGGTATTTTAAAACCAAGTTTTCGTCGTATTTGAAAGATGTCTTGCGTCGGCAAGAAAGTCAG
AAACGCCAGTTTGACAAGATGGCTTATGAGGAGATAGGGGATGTGGCGCATGCGATTCCAGCTGGCGGGTTATGGTTGGA
TGATTATGTGGCCTATCGGGAGGTTTTAGTACAAGTGGAGGAGGCCTTAAGCGAAGCGGATCGGAAGCAGCTTCAGGCCT
TAGTGAGAGGGGAACGGTTCAAGGGGCGTCAGGCTTTGCTTAGGAAGGTTCGTCCTTACTTTAGTGGGTTTGACCAAGGG
TGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

74.214

99.375

0.738
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

74.214

99.375

0.738
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

73.585

99.375

0.731
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

73.585

99.375

0.731
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

72.956

99.375

0.725
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

72.956

99.375

0.725
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

49.333

93.75

0.462
  comX/sigX Streptococcus mutans UA159

49.333

93.75

0.462
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

47.368

95

0.45
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

46.053

95

0.438
  comX/comX1 Streptococcus pneumoniae D39

45.695

94.375

0.431
  comX/comX2 Streptococcus pneumoniae TIGR4

45.695

94.375

0.431
  comX/comX1 Streptococcus pneumoniae TIGR4

45.695

94.375

0.431
  comX/comX2 Streptococcus pneumoniae Rx1

45.695

94.375

0.431
  comX/comX1 Streptococcus pneumoniae Rx1

45.695

94.375

0.431
  comX/comX2 Streptococcus pneumoniae D39

45.695

94.375

0.431
  comX/comX2 Streptococcus pneumoniae R6

45.695

94.375

0.431
  comX/comX1 Streptococcus pneumoniae R6

45.695

94.375

0.431
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

44.737

95

0.425
  comX Streptococcus thermophilus LMD-9

44.371

94.375

0.419
  comX Streptococcus thermophilus LMG 18311

44.371

94.375

0.419
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

44.079

95

0.419
  comX Streptococcus sobrinus strain NIDR 6715-7

44.079

95

0.419
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

44.079

95

0.419
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

44.079

95

0.419
  comX/sigX Streptococcus salivarius strain HSISS4

42.384

94.375

0.4
  comX Streptococcus salivarius SK126

42.384

94.375

0.4
  comX/sigX Streptococcus suis D9

38.71

96.875

0.375
  comX/sigX Streptococcus suis P1/7

38.71

96.875

0.375
  comX/sigX Streptococcus suis isolate S10

38.71

96.875

0.375