Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   WDV80_RS06210 Genome accession   NZ_CP147733
Coordinates   1261457..1261936 (-) Length   159 a.a.
NCBI ID   WP_001204194.1    Uniprot ID   A0AAV3JNR5
Organism   Streptococcus agalactiae strain SagR272_TC     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1261457..1274140 1261457..1261936 within 0


Gene organization within MGE regions


Location: 1261457..1274140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WDV80_RS06210 (WDV80_06210) comX/sigX 1261457..1261936 (-) 480 WP_001204194.1 sigma-70 family RNA polymerase sigma factor Regulator
  WDV80_RS06215 (WDV80_06215) - 1262136..1262555 (-) 420 WP_000784700.1 YjdF family protein -
  WDV80_RS06220 (WDV80_06220) - 1262775..1263326 (-) 552 WP_000161843.1 nucleotidyltransferase family protein -
  WDV80_RS06225 (WDV80_06225) - 1264242..1264412 (-) 171 WP_000840973.1 hypothetical protein -
  WDV80_RS06230 (WDV80_06230) - 1264482..1264913 (-) 432 WP_000761053.1 hypothetical protein -
  WDV80_RS06235 (WDV80_06235) - 1265513..1265827 (-) 315 Protein_1202 transposase -
  WDV80_RS06240 (WDV80_06240) - 1266083..1266490 (+) 408 WP_000351058.1 helix-turn-helix transcriptional regulator -
  WDV80_RS06245 (WDV80_06245) - 1266501..1266833 (+) 333 WP_000181338.1 hypothetical protein -
  WDV80_RS06250 (WDV80_06250) - 1266921..1268050 (-) 1130 Protein_1205 IS3 family transposase -
  WDV80_RS06255 (WDV80_06255) - 1268348..1268803 (-) 456 WP_000021848.1 helix-turn-helix domain-containing protein -
  WDV80_RS06260 (WDV80_06260) - 1269053..1269391 (+) 339 WP_000092752.1 hypothetical protein -
  WDV80_RS06265 (WDV80_06265) - 1269406..1269765 (+) 360 WP_025194534.1 hypothetical protein -
  WDV80_RS06270 (WDV80_06270) - 1270104..1271450 (+) 1347 WP_000088102.1 Rep family protein -
  WDV80_RS06275 (WDV80_06275) - 1271519..1271713 (+) 195 WP_000562208.1 DUF3173 family protein -
  WDV80_RS06280 (WDV80_06280) - 1271718..1272851 (+) 1134 WP_001007677.1 site-specific integrase -
  WDV80_RS06285 (WDV80_06285) - 1272917..1274140 (+) 1224 WP_001003103.1 FRG domain-containing protein -

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19447.28 Da        Isoelectric Point: 6.2639

>NTDB_id=948385 WDV80_RS06210 WP_001204194.1 1261457..1261936(-) (comX/sigX) [Streptococcus agalactiae strain SagR272_TC]
MRDFEELFDKVKPIVMKLRRNYFVQLWEYDDWIQEGRIVLFRLLEEHPYLLDNESKLFIYFKTKFSNYLNDVLRHQDCQK
RQFNKMPYEEISEVSHYVKSKGLVLDDYIAYRDTLTKVEETLSDIDKEKFEKLISGERFAGKKQFIRDIQPFFNAFKAD

Nucleotide


Download         Length: 480 bp        

>NTDB_id=948385 WDV80_RS06210 WP_001204194.1 1261457..1261936(-) (comX/sigX) [Streptococcus agalactiae strain SagR272_TC]
TTGAGAGATTTTGAGGAGTTGTTTGATAAAGTAAAGCCAATCGTAATGAAGCTGAGAAGAAATTATTTTGTTCAACTTTG
GGAATATGATGATTGGATTCAAGAAGGACGTATTGTACTTTTTAGGTTGCTTGAAGAGCATCCGTATTTATTGGATAATG
AAAGCAAACTATTCATTTACTTTAAAACAAAATTTTCAAATTATTTAAACGATGTATTAAGACACCAAGATTGTCAAAAG
CGACAATTTAATAAAATGCCTTATGAAGAAATCAGTGAAGTTAGTCACTATGTTAAGAGTAAAGGACTAGTTTTAGATGA
CTATATTGCTTATCGTGATACTTTAACAAAAGTGGAAGAAACTTTGTCAGATATTGATAAAGAAAAATTTGAAAAACTGA
TTAGTGGTGAACGTTTTGCGGGGAAGAAACAATTCATACGAGATATTCAACCTTTTTTCAATGCTTTTAAAGCGGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

56.688

98.742

0.56
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

52.349

93.711

0.491
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

52.349

93.711

0.491
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

52.349

93.711

0.491
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

52.349

93.711

0.491
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

52

94.34

0.491
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

52

94.34

0.491
  comX/sigX Streptococcus mutans UA159

49.677

97.484

0.484
  comX Streptococcus sobrinus strain NIDR 6715-7

43.59

98.113

0.428
  comX/sigX Streptococcus suis D9

43.226

97.484

0.421
  comX/sigX Streptococcus suis isolate S10

43.226

97.484

0.421
  comX/sigX Streptococcus suis P1/7

43.226

97.484

0.421
  comX Streptococcus thermophilus LMD-9

42.177

92.453

0.39
  comX Streptococcus thermophilus LMG 18311

42.177

92.453

0.39
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

39.869

96.226

0.384
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

39.869

96.226

0.384
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

39.869

96.226

0.384
  comX/comX2 Streptococcus pneumoniae Rx1

40.397

94.969

0.384
  comX/comX2 Streptococcus pneumoniae TIGR4

40.397

94.969

0.384
  comX/comX1 Streptococcus pneumoniae TIGR4

40.397

94.969

0.384
  comX/comX1 Streptococcus pneumoniae Rx1

40.397

94.969

0.384
  comX/comX2 Streptococcus pneumoniae D39

40.397

94.969

0.384
  comX/comX1 Streptococcus pneumoniae D39

40.397

94.969

0.384
  comX/comX2 Streptococcus pneumoniae R6

40.397

94.969

0.384
  comX/comX1 Streptococcus pneumoniae R6

40.397

94.969

0.384
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

39.216

96.226

0.377
  comX Streptococcus salivarius SK126

40.816

92.453

0.377
  comX/sigX Streptococcus salivarius strain HSISS4

40.816

92.453

0.377
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

38.562

96.226

0.371