Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   U0N78_RS00085 Genome accession   NZ_CP140109
Coordinates   15986..16456 (+) Length   156 a.a.
NCBI ID   WP_172045800.1    Uniprot ID   A0A7T1LA54
Organism   Streptococcus suis strain 2022WUSS148     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 10986..21456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0N78_RS00070 (U0N78_00070) tilS 11824..13092 (+) 1269 WP_172045798.1 tRNA lysidine(34) synthetase TilS -
  U0N78_RS00075 (U0N78_00075) hpt 13100..13642 (+) 543 WP_256769047.1 hypoxanthine phosphoribosyltransferase -
  U0N78_RS00080 (U0N78_00080) ftsH 13664..15634 (+) 1971 WP_172045799.1 ATP-dependent zinc metalloprotease FtsH -
  U0N78_RS00085 (U0N78_00085) comX/sigX 15986..16456 (+) 471 WP_172045800.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 156 a.a.        Molecular weight: 19060.96 Da        Isoelectric Point: 8.4522

>NTDB_id=912552 U0N78_RS00085 WP_172045800.1 15986..16456(+) (comX/sigX) [Streptococcus suis strain 2022WUSS148]
MEFEKVYASVKGIVNKARKEFYIKLWDQDDWEQEGMMTLFELLEAQPWLVDEQVQLYCYFKVKFRNRIKDRIRKQESQKR
KFDRMLHEDIHELSHAIQSPGLINDELLMLRGALRDYRKNLSNDQLDKYEKLISGQCFNGRREMIRDLQIHLKDFR

Nucleotide


Download         Length: 471 bp        

>NTDB_id=912552 U0N78_RS00085 WP_172045800.1 15986..16456(+) (comX/sigX) [Streptococcus suis strain 2022WUSS148]
ATGGAATTCGAAAAAGTGTACGCAAGCGTCAAAGGTATTGTAAACAAGGCTCGAAAAGAGTTTTACATTAAACTATGGGA
TCAAGATGATTGGGAACAAGAAGGAATGATGACCTTATTTGAATTGTTGGAAGCGCAACCGTGGCTAGTTGATGAACAAG
TTCAATTATATTGTTATTTTAAAGTCAAGTTCAGAAATCGCATCAAAGATCGTATCCGCAAACAGGAAAGTCAAAAACGC
AAGTTTGACCGAATGCTACATGAAGATATTCACGAATTATCTCATGCAATACAATCACCGGGATTGATAAACGATGAACT
ATTAATGTTGAGAGGTGCCTTGAGAGATTATCGAAAAAATCTGAGTAATGATCAACTTGATAAATACGAAAAATTAATTA
GCGGACAATGTTTTAATGGTCGTCGTGAAATGATACGTGATTTACAAATTCATTTGAAAGACTTTCGCTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T1LA54

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus suis D9

98.718

100

0.987
  comX/sigX Streptococcus suis isolate S10

98.077

100

0.981
  comX/sigX Streptococcus suis P1/7

98.077

100

0.981
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

48.387

99.359

0.481
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

48.387

99.359

0.481
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

45.098

98.077

0.442
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

45.098

98.077

0.442
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

45.098

98.077

0.442
  comX/comX1 Streptococcus pneumoniae TIGR4

45.695

96.795

0.442
  comX/comX2 Streptococcus pneumoniae TIGR4

45.695

96.795

0.442
  comX/comX2 Streptococcus pneumoniae R6

45.033

96.795

0.436
  comX/comX2 Streptococcus pneumoniae Rx1

45.033

96.795

0.436
  comX/comX1 Streptococcus pneumoniae Rx1

45.033

96.795

0.436
  comX/comX2 Streptococcus pneumoniae D39

45.033

96.795

0.436
  comX/comX1 Streptococcus pneumoniae D39

45.033

96.795

0.436
  comX/comX1 Streptococcus pneumoniae R6

45.033

96.795

0.436
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

43.791

98.077

0.429
  comX/sigX Streptococcus mutans UA159

42.581

99.359

0.423
  comX Streptococcus thermophilus LMG 18311

41.176

98.077

0.404
  comX Streptococcus thermophilus LMD-9

41.176

98.077

0.404
  comX Streptococcus sobrinus strain NIDR 6715-7

40.523

98.077

0.397
  comX/sigX Streptococcus salivarius strain HSISS4

40.523

98.077

0.397
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

40

99.359

0.397
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

40

99.359

0.397
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

39.355

99.359

0.391
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

39.355

99.359

0.391
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

39.355

99.359

0.391
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

39.355

99.359

0.391
  comX Streptococcus salivarius SK126

39.869

98.077

0.391
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.217

100

0.385