Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   RRU92_RS01460 Genome accession   NZ_CP135436
Coordinates   297591..298055 (-) Length   154 a.a.
NCBI ID   WP_315640094.1    Uniprot ID   A0AA96MQ59
Organism   Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 292591..303055
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RRU92_RS01460 (RRU92_01460) comX/sigX/comX2/sigX2 297591..298055 (-) 465 WP_315640094.1 sigma-70 family RNA polymerase sigma factor Regulator
  RRU92_RS01465 (RRU92_01465) pbp2a 298228..300453 (-) 2226 WP_315640095.1 penicillin-binding protein PBP2A -
  RRU92_RS01470 (RRU92_01470) - 300542..301417 (+) 876 WP_148131560.1 RluA family pseudouridine synthase -
  RRU92_RS01475 (RRU92_01475) gap 301494..302504 (-) 1011 WP_049492462.1 type I glyceraldehyde-3-phosphate dehydrogenase -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 19182.99 Da        Isoelectric Point: 7.9132

>NTDB_id=886506 RRU92_RS01460 WP_315640094.1 297591..298055(-) (comX/sigX/comX2/sigX2) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MLEKYYEKVKGIVHRCRKDYYLHLWEKEDWDQEGMFCLHELLEKHPELVEEEKKLYVYFKTKFRNRILDSVRKQESQKRR
LDRMAYEEVGEISHRLPEGGLWLDDYYALHELLNSYRRKLPQDKQEAYERLWADERFKGRKALLRELKEVIQEK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=886506 RRU92_RS01460 WP_315640094.1 297591..298055(-) (comX/sigX/comX2/sigX2) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGCTTGAAAAGTATTATGAGAAGGTAAAAGGAATTGTCCATAGATGTCGAAAAGATTACTATCTCCACCTGTGGGAGAA
AGAGGATTGGGATCAAGAAGGCATGTTCTGTCTCCATGAACTTCTAGAAAAGCATCCAGAACTGGTGGAAGAAGAAAAGA
AACTCTACGTCTACTTCAAAACAAAATTTCGCAATCGAATCCTTGATAGTGTCAGAAAACAAGAGAGTCAAAAACGTCGC
CTAGACCGAATGGCCTATGAAGAAGTAGGAGAAATTAGCCATCGCCTACCAGAAGGAGGATTGTGGCTGGATGATTACTA
CGCTCTTCATGAATTATTGAATAGTTATAGAAGAAAGTTACCACAAGATAAGCAAGAAGCCTACGAACGCCTCTGGGCAG
ACGAACGATTTAAAGGCCGCAAAGCCCTTCTCAGAGAGCTGAAGGAAGTAATTCAGGAGAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

62.745

99.351

0.623
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

62.092

99.351

0.617
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

61.438

99.351

0.61
  comX/comX2 Streptococcus pneumoniae D39

60.784

99.351

0.604
  comX/comX1 Streptococcus pneumoniae D39

60.784

99.351

0.604
  comX/comX2 Streptococcus pneumoniae R6

60.784

99.351

0.604
  comX/comX1 Streptococcus pneumoniae R6

60.784

99.351

0.604
  comX/comX2 Streptococcus pneumoniae Rx1

60.784

99.351

0.604
  comX/comX1 Streptococcus pneumoniae Rx1

60.784

99.351

0.604
  comX/comX1 Streptococcus pneumoniae TIGR4

60.131

99.351

0.597
  comX/comX2 Streptococcus pneumoniae TIGR4

60.131

99.351

0.597
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

60.131

99.351

0.597
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

58.904

94.805

0.558
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

58.904

94.805

0.558
  comX/sigX Streptococcus mutans UA159

51.02

95.455

0.487
  comX/sigX Streptococcus suis D9

48.98

95.455

0.468
  comX/sigX Streptococcus suis isolate S10

48.98

95.455

0.468
  comX/sigX Streptococcus suis P1/7

48.98

95.455

0.468
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

47.973

96.104

0.461
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

47.973

96.104

0.461
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

47.973

96.104

0.461
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

47.973

96.104

0.461
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

47.973

96.104

0.461
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

47.973

96.104

0.461
  comX/sigX Streptococcus salivarius strain HSISS4

44.755

92.857

0.416
  comX Streptococcus salivarius SK126

44.755

92.857

0.416
  comX Streptococcus thermophilus LMG 18311

42.759

94.156

0.403
  comX Streptococcus thermophilus LMD-9

42.759

94.156

0.403
  comX Streptococcus sobrinus strain NIDR 6715-7

43.357

92.857

0.403
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

42.177

95.455

0.403