Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   P8P68_RS06145 Genome accession   NZ_CP121467
Coordinates   1270044..1270517 (-) Length   157 a.a.
NCBI ID   WP_001049305.1    Uniprot ID   K0ZQB4
Organism   Streptococcus sp. D7B5     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1265044..1275517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8P68_RS06145 (P8P68_06145) comX/comX2 1270044..1270517 (-) 474 WP_001049305.1 hypothetical protein Regulator
  P8P68_RS06150 (P8P68_06150) nusG 1270638..1271174 (-) 537 WP_000376732.1 transcription termination/antitermination protein NusG -
  P8P68_RS06155 (P8P68_06155) secE 1271233..1271409 (-) 177 WP_000505776.1 preprotein translocase subunit SecE -
  P8P68_RS06160 (P8P68_06160) rpmG 1271419..1271571 (-) 153 WP_001809375.1 50S ribosomal protein L33 -
  P8P68_RS06165 (P8P68_06165) pbp2a 1271624..1273819 (-) 2196 WP_000762641.1 penicillin-binding protein PBP2A -
  P8P68_RS06170 (P8P68_06170) - 1273906..1274781 (+) 876 WP_001160826.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19280.16 Da        Isoelectric Point: 7.7801

>NTDB_id=812228 P8P68_RS06145 WP_001049305.1 1270044..1270517(-) (comX/comX2) [Streptococcus sp. D7B5]
MNLKDLYEESKGIVHKCRKDYHLHLWEKEDWDQEGMLCLYELVSCNPELLEGERHRLYVCFKTKFRNRILDYIRKQESHK
RRFDKEPYEEVSEISHRLGEKGLRLDDYYLFHELLKNYKSKQSMEKQELIDRLMGGEVFRGRKALLRELSLIFSEFR

Nucleotide


Download         Length: 474 bp        

>NTDB_id=812228 P8P68_RS06145 WP_001049305.1 1270044..1270517(-) (comX/comX2) [Streptococcus sp. D7B5]
ATGAATCTAAAAGACTTATATGAAGAAAGCAAGGGAATCGTCCATAAGTGTCGCAAAGATTATCATTTGCATCTGTGGGA
GAAAGAGGACTGGGATCAGGAAGGCATGTTATGTCTGTATGAGCTGGTGAGTTGCAACCCAGAGTTACTAGAGGGGGAGC
GCCATCGACTTTATGTCTGCTTTAAAACAAAGTTTAGAAATCGTATCCTAGATTACATCCGTAAACAGGAAAGCCACAAG
CGCCGTTTTGACAAAGAACCCTATGAAGAGGTGAGTGAGATTAGCCATCGTCTAGGAGAGAAAGGACTCAGGCTGGACGA
TTATTATCTCTTTCACGAACTTCTAAAGAATTACAAATCAAAGCAGAGTATGGAAAAACAAGAATTAATAGACCGTCTAA
TGGGAGGAGAAGTCTTTAGAGGACGTAAAGCTCTCCTGAGAGAACTTTCCCTTATCTTTTCAGAATTTCGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K0ZQB4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

64.935

98.089

0.637
  comX/comX2 Streptococcus pneumoniae D39

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae D39

64.935

98.089

0.637
  comX/comX2 Streptococcus pneumoniae R6

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae R6

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae Rx1

64.935

98.089

0.637
  comX/comX2 Streptococcus pneumoniae TIGR4

64.286

98.089

0.631
  comX/comX1 Streptococcus pneumoniae TIGR4

64.286

98.089

0.631
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

64.286

98.089

0.631
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

63.636

98.089

0.624
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

62.987

98.089

0.618
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

62.987

98.089

0.618
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comX/sigX Streptococcus mutans UA159

46.711

96.815

0.452
  comX/sigX Streptococcus suis isolate S10

40.764

100

0.408
  comX/sigX Streptococcus suis D9

40.764

100

0.408
  comX/sigX Streptococcus suis P1/7

40.764

100

0.408
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.744

99.363

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.744

99.363

0.395
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

39.744

99.363

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

39.744

99.363

0.395
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

39.744

99.363

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

39.744

99.363

0.395
  comX Streptococcus thermophilus LMD-9

40

95.541

0.382
  comX/sigX Streptococcus salivarius strain HSISS4

40

95.541

0.382
  comX Streptococcus thermophilus LMG 18311

40

95.541

0.382
  comX Streptococcus salivarius SK126

40

95.541

0.382
  comX Streptococcus sobrinus strain NIDR 6715-7

41.958

91.083

0.382
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.342

100

0.376