Detailed information NTG0803868

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: P3U54_RS00320
• Genome accession: NZ_CP120155
• Coordinates: 65938..67566 (-)
• Length: 542 a.a.
• NCBI ID: WP_323710788.1
• Uniprot ID: -
• Organism: Mammaliicoccus lentus strain Dog026
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	47768..67566	65938..67566	within	0

Gene organization within MGE regions

Location: 47768..67566

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3U54_RS00225 (P3U54_00225)	mecA	47768..49777 (-)	2010	WP_063852655.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
P3U54_RS00230 (P3U54_00230)	mecR1	49874..51631 (+)	1758	WP_000952923.1	beta-lactam sensor/signal transducer MecR1	-
P3U54_RS00235 (P3U54_00235)	mecI	51631..52002 (+)	372	WP_000369214.1	mecA-type methicillin resistance repressor MecI	-
P3U54_RS00240 (P3U54_00240)	psm-mec	52087..52155 (-)	69	WP_014532405.1	phenol-soluble modulin PSM-mec	-
P3U54_RS00245 (P3U54_00245)	-	52475..53623 (+)	1149	WP_000427807.1	ROK family transcriptional regulator	-
P3U54_RS00250 (P3U54_00250)	cstB	53737..55071 (-)	1335	Protein_49	persulfide dioxygenase-sulfurtransferase CstB	-
P3U54_RS00255 (P3U54_00255)	-	55105..56169 (-)	1065	WP_000438836.1	DsrE/DsrF/DrsH-like family protein	-
P3U54_RS00260 (P3U54_00260)	cstR	56305..56565 (+)	261	WP_000220507.1	persulfide-sensing transcriptional repressor CstR	-
P3U54_RS00265 (P3U54_00265)	-	56565..57203 (+)	639	Protein_52	sulfite exporter TauE/SafE family protein	-
P3U54_RS00270 (P3U54_00270)	-	57477..58094 (-)	618	WP_000562107.1	CadD family cadmium resistance transporter	-
P3U54_RS00275 (P3U54_00275)	-	58175..60589 (-)	2415	WP_000378485.1	cadmium-translocating P-type ATPase CadA	-
P3U54_RS00280 (P3U54_00280)	-	60582..60947 (-)	366	WP_000159127.1	ArsR/SmtB family transcription factor	-
P3U54_RS00285 (P3U54_00285)	-	61185..61562 (-)	378	WP_001041908.1	DUF6262 family protein	-
P3U54_RS00290 (P3U54_00290)	-	61569..63461 (-)	1893	WP_002485298.1	site-specific integrase	-
P3U54_RS00295 (P3U54_00295)	-	63656..63979 (-)	324	WP_000088091.1	JAB domain-containing protein	-
P3U54_RS00300 (P3U54_00300)	-	63972..64178 (-)	207	WP_001077283.1	hypothetical protein	-
P3U54_RS00305 (P3U54_00305)	-	64180..64701 (-)	522	WP_000836008.1	DUF1643 domain-containing protein	-
P3U54_RS00310 (P3U54_00310)	-	64721..65032 (-)	312	WP_201101506.1	DUF960 family protein	-
P3U54_RS00315 (P3U54_00315)	-	65117..65467 (-)	351	WP_194376028.1	SAUGI family uracil-DNA glycosylase inhibitor	-
P3U54_RS00320 (P3U54_00320)	ccrB	65938..67566 (-)	1629	WP_323710788.1	cassette chromosome recombinase CcrB	Machinery gene

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62386.41 Da
• Isoelectric Point: 9.7743

>NTDB_id=803868 P3U54_RS00320 WP_323710788.1 65938..67566(-) (ccrB) [Mammaliicoccus lentus strain Dog026]
MLQLKQKRVGIYVRVSTETQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSINSITYILVNPFYIGKIQFAK
YKDWNEKRRKGLNDKPIIADGKHPPIISQELWDKVQSRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQVLEIVKCDKVINKVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTTILKETIHKYKTQLTDITNQINQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide

• Length: 1629 bp

>NTDB_id=803868 P3U54_RS00320 WP_323710788.1 65938..67566(-) (ccrB) [Mammaliicoccus lentus strain Dog026]
ATGCTACAACTTAAACAAAAACGTGTCGGTATCTATGTCCGTGTATCAACAGAAACGCAAAGTACTGAAGGATATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATCGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAATCAACATGAAGCCAATATTGTAAAATA
TATATTTGAGTCATATGCTAAAGGTCATGGTTATCGTAAAATAGCCAATGCCCTCAATCACAAAGGCTATGTTACTAAAA
AAGGTAATCCTTTTAGCATCAATTCAATAACCTATATCTTAGTCAATCCATTCTACATTGGTAAAATTCAATTTGCGAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAGGGACTGAATGATAAACCTATTATAGCTGATGGTAAACACCCTCCTATTAT
TAGTCAAGAATTATGGGATAAAGTCCAATCACGCAAAAAACAGGTCAGTCAAAAACCTCAAGTTCATGGAAAAGGAACCA
ATCTATTAACAGGTATTATTCACTGCCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACAAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGCTATTATTCTTGTAGTAACTTCCGAAACAAAGGTTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGACGTAATTGAGAAATACGTTATGGATCAAGTACTCGAAATTGTCAAATGTGATAAAGTCATTAATAAAGTCT
TAGAACGTGTCAATCAAGAGAATAAAGTCGATATTGGTGCATTGAACCATGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCAGACTTAACAACAATACTCAAAGAAACAAT
CCATAAATATAAAACACAACTGACTGACATTACGAATCAAATTAATCAACTTAAGCAACAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

• Resolvase, N terminal domain (Resolvase) (11-156)

• Recombinase (Recombinase) (180-280)

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	85.609	100	0.856