Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   PW252_RS10975 Genome accession   NZ_CP118735
Coordinates   2263693..2264163 (-) Length   156 a.a.
NCBI ID   WP_316716864.1    Uniprot ID   -
Organism   Streptococcus iners strain 29887     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2258693..2269163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS10955 (PW252_10950) - 2259346..2260143 (-) 798 WP_248049174.1 PepSY domain-containing protein -
  PW252_RS10960 (PW252_10955) - 2260418..2261992 (-) 1575 WP_248049172.1 M56 family metallopeptidase -
  PW252_RS10965 (PW252_10960) - 2262013..2262381 (-) 369 WP_248049169.1 BlaI/MecI/CopY family transcriptional regulator -
  PW252_RS10970 (PW252_10965) - 2262513..2263526 (-) 1014 WP_248049166.1 glycosyltransferase family 2 protein -
  PW252_RS10975 (PW252_10970) comX/sigX 2263693..2264163 (-) 471 WP_316716864.1 sigma-70 family RNA polymerase sigma factor Regulator
  PW252_RS10980 (PW252_10975) rpsD 2264366..2264977 (-) 612 WP_024407736.1 30S ribosomal protein S4 -
  PW252_RS10985 (PW252_10980) - 2265192..2265755 (-) 564 WP_248049159.1 TlpA family protein disulfide reductase -
  PW252_RS10990 (PW252_10985) - 2265774..2266469 (-) 696 WP_248049156.1 cytochrome c biogenesis CcdA family protein -
  PW252_RS10995 (PW252_10990) - 2266608..2266859 (-) 252 WP_105114079.1 Veg family protein -
  PW252_RS11000 (PW252_10995) dnaB 2266863..2268218 (-) 1356 WP_105144111.1 replicative DNA helicase -
  PW252_RS11005 (PW252_11000) rplI 2268252..2268704 (-) 453 WP_105125009.1 50S ribosomal protein L9 -

Sequence

Protein


Download         Length: 156 a.a.        Molecular weight: 19075.89 Da        Isoelectric Point: 7.8908

>NTDB_id=794759 PW252_RS10975 WP_316716864.1 2263693..2264163(-) (comX/sigX) [Streptococcus iners strain 29887]
MEFEKVYDSVKGIVNKARKEFYIKLWDRDDWEQEGMMTLFELLEEQPWLIGERVQLYCYFKVKFRNRVKDRVRRQESQKR
KFDRLPHEDIHDLSHLIQSPGLVNDELLMLRGALRDYRKNLSMDQLENYEKLISGQSFNGRKNMLRDLQEHLKDFC

Nucleotide


Download         Length: 471 bp        

>NTDB_id=794759 PW252_RS10975 WP_316716864.1 2263693..2264163(-) (comX/sigX) [Streptococcus iners strain 29887]
ATGGAATTTGAAAAGGTGTATGATAGCGTAAAAGGGATTGTCAACAAGGCTCGTAAAGAGTTTTATATCAAACTGTGGGA
CAGAGATGATTGGGAACAAGAAGGCATGATGACTTTGTTCGAACTATTGGAAGAGCAGCCTTGGTTGATTGGGGAAAGAG
TTCAGCTGTATTGTTATTTCAAGGTTAAATTCCGAAATCGGGTTAAGGACCGAGTTCGCAGACAGGAAAGTCAGAAGCGC
AAGTTTGACCGTTTGCCTCATGAAGATATTCACGACCTATCACATCTCATCCAATCACCTGGTTTGGTTAATGACGAGCT
ATTGATGTTGAGAGGTGCCTTGAGAGATTATCGGAAAAATTTGTCTATGGACCAATTGGAAAATTACGAAAAACTCATCA
GTGGTCAGAGTTTCAATGGTCGCAAGAATATGCTTCGGGATTTGCAAGAACACTTAAAGGATTTTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus suis D9

87.097

99.359

0.865
  comX/sigX Streptococcus suis isolate S10

86.452

99.359

0.859
  comX/sigX Streptococcus suis P1/7

86.452

99.359

0.859
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

48.387

99.359

0.481
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

48.387

99.359

0.481
  comX/sigX Streptococcus mutans UA159

43.506

98.718

0.429
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

43.137

98.077

0.423
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

43.137

98.077

0.423
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

42.484

98.077

0.417
  comX/comX1 Streptococcus pneumoniae TIGR4

42.763

97.436

0.417
  comX/comX2 Streptococcus pneumoniae TIGR4

42.763

97.436

0.417
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

41.026

100

0.41
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

41.026

100

0.41
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

41.83

98.077

0.41
  comX/comX1 Streptococcus pneumoniae R6

42.105

97.436

0.41
  comX/comX2 Streptococcus pneumoniae Rx1

42.105

97.436

0.41
  comX/comX1 Streptococcus pneumoniae Rx1

42.105

97.436

0.41
  comX/comX2 Streptococcus pneumoniae D39

42.105

97.436

0.41
  comX/comX1 Streptococcus pneumoniae D39

42.105

97.436

0.41
  comX/comX2 Streptococcus pneumoniae R6

42.105

97.436

0.41
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40.385

100

0.404
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40.385

100

0.404
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40.385

100

0.404
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40.385

100

0.404
  comX Streptococcus thermophilus LMD-9

41.176

98.077

0.404
  comX Streptococcus thermophilus LMG 18311

41.176

98.077

0.404
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.744

100

0.397
  comX/sigX Streptococcus salivarius strain HSISS4

40.523

98.077

0.397
  comX Streptococcus salivarius SK126

40.523

98.077

0.397
  comX Streptococcus sobrinus strain NIDR 6715-7

37.255

98.077

0.365