Detailed information NTG0079293

Bioinformatically predicted

Overview

• Name: pilA2
• Type: Machinery gene
• Locus tag: HRS36_RS05755
• Genome accession: NZ_AP022839
• Coordinates: 1190827..1191237 (+)
• Length: 136 a.a.
• NCBI ID: WP_173236568.1
• Uniprot ID: A0A6F8T2W9
• Organism: Legionella antarctica strain TUM19329
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1185827..1196237

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HRS36_RS05730 (TUM19329_11350)	tsaB	1186834..1187502 (+)	669	WP_173236563.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	-
HRS36_RS05735 (TUM19329_11360)	-	1187495..1187674 (+)	180	WP_173236564.1	Trm112 family protein	-
HRS36_RS05740 (TUM19329_11370)	kdsB	1187671..1188423 (+)	753	WP_173236565.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
HRS36_RS05745 (TUM19329_11380)	-	1188655..1190052 (-)	1398	WP_173236566.1	APC family permease	-
HRS36_RS05750 (TUM19329_11390)	-	1190162..1190485 (-)	324	WP_173236567.1	BolA family protein	-
HRS36_RS05755 (TUM19329_11400)	pilA2	1190827..1191237 (+)	411	WP_173236568.1	pilin	Machinery gene
HRS36_RS05760 (TUM19329_11410)	-	1191302..1192540 (-)	1239	WP_173236569.1	6-phosphofructokinase	-
HRS36_RS05765 (TUM19329_11420)	letS	1192604..1195342 (-)	2739	WP_173238470.1	two-component system sensor histidine kinase LetS	Regulator

Sequence

Protein

• Length: 136 a.a.
• Molecular weight: 13918.06 Da
• Isoelectric Point: 6.1220

>NTDB_id=79293 HRS36_RS05755 WP_173236568.1 1190827..1191237(+) (pilA2) [Legionella antarctica strain TUM19329]
MKQKGFTLIELMIVVAIIGILAAIAIPAYQDYTIRARVTEGLQMASSAQLAVSETAITNNALPATQAATGYTSPAPTANV
ASITITDATGVIVITYTAAAGNGTLTLTPTLTANGDVTWNCSVGTLLPKYAPASCR

Nucleotide

• Length: 411 bp

>NTDB_id=79293 HRS36_RS05755 WP_173236568.1 1190827..1191237(+) (pilA2) [Legionella antarctica strain TUM19329]
ATGAAACAGAAGGGTTTTACGCTGATTGAATTGATGATAGTTGTGGCAATTATTGGTATTTTAGCTGCTATCGCTATTCC
AGCTTATCAGGACTATACGATTAGAGCGCGGGTGACTGAGGGCTTGCAAATGGCTTCATCAGCACAACTTGCAGTTTCAG
AAACTGCAATTACCAATAACGCATTACCAGCTACTCAAGCAGCTACAGGTTATACCAGCCCTGCGCCTACTGCGAATGTT
GCTTCTATTACCATAACGGACGCCACAGGTGTGATTGTTATAACCTACACGGCCGCCGCCGGTAATGGAACCTTAACCTT
AACACCTACTCTAACAGCTAATGGAGATGTGACTTGGAATTGTAGTGTGGGAACTTTGTTACCAAAATATGCTCCTGCAA
GTTGCAGATAA

Domains

Predicted by InterproScan.

• Pilin (bacterial filament) (Pilin) (35-136)

• Prokaryotic N-terminal methylation motif (N_methyl) (1-25)

3D structure

• AlphaFold DB: A0A6F8T2W9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA2	Legionella pneumophila str. Paris	83.088	100	0.831
pilA2	Legionella pneumophila strain ERS1305867	82.353	100	0.824
pilA	Ralstonia pseudosolanacearum GMI1000	49.689	100	0.588
comP	Acinetobacter baylyi ADP1	51.034	100	0.544
pilE	Neisseria elongata subsp. glycolytica ATCC 29315	36.413	100	0.493
pilA/pilA1	Eikenella corrodens VA1	41.892	100	0.456
pilA	Haemophilus influenzae Rd KW20	46.032	92.647	0.426
pilA/pilAI	Pseudomonas stutzeri DSM 10701	41.912	100	0.419
pilA	Acinetobacter baumannii strain A118	41.304	100	0.419
pilA	Vibrio cholerae strain A1552	38.028	100	0.397
pilA	Vibrio cholerae C6706	38.028	100	0.397
pilA	Vibrio cholerae O1 biovar El Tor strain E7946	38.028	100	0.397
pilA	Haemophilus influenzae 86-028NP	42.742	91.176	0.39
pilA	Vibrio parahaemolyticus RIMD 2210633	39.695	96.324	0.382
pilA/pilAII	Pseudomonas stutzeri DSM 10701	38.806	98.529	0.382
pilE	Neisseria gonorrhoeae MS11	40.157	93.382	0.375
pilA	Glaesserella parasuis strain SC1401	37.313	98.529	0.368
pilA	Pseudomonas aeruginosa PAK	39.062	94.118	0.368