Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   PUW49_RS09570 Genome accession   NZ_CP118054
Coordinates   1883105..1883578 (-) Length   157 a.a.
NCBI ID   WP_070242004.1    Uniprot ID   -
Organism   Streptococcus anginosus strain VSI37     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1878105..1888578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW49_RS09530 (PUW49_09530) - 1878241..1879177 (-) 937 Protein_1842 IS30 family transposase -
  PUW49_RS09535 (PUW49_09535) - 1879361..1879729 (-) 369 WP_004224594.1 EXLDI protein -
  PUW49_RS09540 (PUW49_09540) - 1879866..1880432 (-) 567 Protein_1844 NAD(P)H-dependent oxidoreductase -
  PUW49_RS09545 (PUW49_09545) - 1880429..1881025 (-) 597 WP_024052411.1 TetR/AcrR family transcriptional regulator -
  PUW49_RS09550 (PUW49_09550) - 1881175..1881477 (-) 303 WP_224783687.1 hypothetical protein -
  PUW49_RS09555 (PUW49_09555) - 1881474..1881623 (-) 150 WP_224783688.1 hypothetical protein -
  PUW49_RS09560 (PUW49_09560) - 1881706..1882068 (-) 363 WP_224783689.1 LacI family DNA-binding transcriptional regulator -
  PUW49_RS09565 (PUW49_09565) - 1882103..1882912 (-) 810 Protein_1849 HAD family hydrolase -
  PUW49_RS09570 (PUW49_09570) comR/comR2 1883105..1883578 (-) 474 WP_070242004.1 sigma-70 family RNA polymerase sigma factor Regulator
  PUW49_RS09575 (PUW49_09575) nusB 1883795..1884220 (-) 426 WP_003037723.1 transcription antitermination factor NusB -
  PUW49_RS09580 (PUW49_09580) - 1884213..1884602 (-) 390 WP_003037725.1 Asp23/Gls24 family envelope stress response protein -
  PUW49_RS09585 (PUW49_09585) efp 1884712..1885272 (-) 561 WP_003026309.1 elongation factor P -
  PUW49_RS09590 (PUW49_09590) - 1885331..1886392 (-) 1062 WP_024052417.1 Xaa-Pro peptidase family protein -
  PUW49_RS09595 (PUW49_09595) hxlB 1886777..1887316 (-) 540 WP_070654278.1 6-phospho-3-hexuloisomerase -
  PUW49_RS09600 (PUW49_09600) - 1887334..1887786 (-) 453 WP_070654279.1 PTS sugar transporter subunit IIA -
  PUW49_RS09605 (PUW49_09605) - 1887796..1888086 (-) 291 WP_024052420.1 PTS sugar transporter subunit IIB -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19208.01 Da        Isoelectric Point: 7.2703

>NTDB_id=789690 PUW49_RS09570 WP_070242004.1 1883105..1883578(-) (comR/comR2) [Streptococcus anginosus strain VSI37]
MEFKELYAKVRGIVLKCRREYYIHLWELSDWDQEGMLVLYQLVSQYPQLVEAESQLYVYYKTKFRNHILDILRKQESQKR
KLNRQAYEEVSEIGHKLSLKELYLDELVILRDQLNSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide


Download         Length: 474 bp        

>NTDB_id=789690 PUW49_RS09570 WP_070242004.1 1883105..1883578(-) (comR/comR2) [Streptococcus anginosus strain VSI37]
ATGGAGTTCAAGGAGTTATATGCCAAGGTGAGAGGAATCGTACTGAAATGTCGGAGGGAATATTATATCCACCTGTGGGA
GTTAAGTGATTGGGACCAAGAGGGAATGTTGGTGCTCTATCAGTTGGTAAGCCAGTATCCGCAGCTGGTAGAAGCAGAAA
GTCAGCTCTATGTTTACTATAAGACCAAGTTCCGCAATCATATCCTGGACATCCTCCGTAAACAGGAAAGTCAAAAACGC
AAACTTAATCGTCAAGCTTATGAAGAAGTGAGCGAGATTGGTCACAAGCTCAGCCTAAAAGAACTATATCTGGATGAATT
GGTGATTCTCCGAGACCAGCTAAATAGCTATCAAGCTCAACTGAGCCCAGAGAAACAGGAGCAGTATGAGCGCTTACTAG
CCGATGAACGGTTCAAAGGCCGCCAAGCCATGATTCGAGAATTAAGAGCCTACTTAAAAGATTATAGTGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

59.615

99.363

0.592
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

59.615

99.363

0.592
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

53.896

98.089

0.529
  comX/comX2 Streptococcus pneumoniae D39

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae D39

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae R6

53.247

98.089

0.522
  comX/comX2 Streptococcus pneumoniae R6

53.247

98.089

0.522
  comX/comX2 Streptococcus pneumoniae Rx1

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae Rx1

53.247

98.089

0.522
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

53.247

98.089

0.522
  comX/comX2 Streptococcus pneumoniae TIGR4

52.597

98.089

0.516
  comX/comX1 Streptococcus pneumoniae TIGR4

52.597

98.089

0.516
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

52.597

98.089

0.516
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

52.597

98.089

0.516
  comX/sigX Streptococcus mutans UA159

50

99.363

0.497
  comX/sigX Streptococcus suis D9

47.742

98.726

0.471
  comX/sigX Streptococcus suis isolate S10

47.742

98.726

0.471
  comX/sigX Streptococcus suis P1/7

47.742

98.726

0.471
  comX Streptococcus salivarius SK126

46.104

98.089

0.452
  comX/sigX Streptococcus salivarius strain HSISS4

45.455

98.089

0.446
  comX Streptococcus thermophilus LMG 18311

45.455

98.089

0.446
  comX Streptococcus thermophilus LMD-9

45.455

98.089

0.446
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.308

99.363

0.42
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

42.308

99.363

0.42
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.308

99.363

0.42
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.462

99.363

0.382
  comX Streptococcus sobrinus strain NIDR 6715-7

37.662

98.089

0.369