Detailed information
Bioinformatically predicted
Overview
| Name | comR/comR2 | Type | Regulator |
| Locus tag | PUW49_RS00075 | Genome accession | NZ_CP118054 |
| Coordinates | 14880..15353 (+) | Length | 157 a.a. |
| NCBI ID | WP_024053280.1 | Uniprot ID | - |
| Organism | Streptococcus anginosus strain VSI37 | ||
| Function | activate transcription of late competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 12708..42492 | 14880..15353 | within | 0 |
| IS/Tn | 15411..16043 | 14880..15353 | flank | 58 |
Gene organization within MGE regions
Location: 12708..42492
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PUW49_RS00070 (PUW49_00070) | ftsH | 12708..14677 (+) | 1970 | Protein_13 | ATP-dependent zinc metalloprotease FtsH | - |
| PUW49_RS00075 (PUW49_00075) | comR/comR2 | 14880..15353 (+) | 474 | WP_024053280.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| PUW49_RS00080 (PUW49_00080) | - | 15411..16327 (-) | 917 | Protein_15 | IS30 family transposase | - |
| PUW49_RS00195 (PUW49_00195) | mreC | 23624..24430 (+) | 807 | WP_024052914.1 | rod shape-determining protein MreC | - |
| PUW49_RS00200 (PUW49_00200) | mreD | 24432..24932 (+) | 501 | WP_024052913.1 | rod shape-determining protein MreD | - |
| PUW49_RS00205 (PUW49_00205) | - | 25042..26232 (+) | 1191 | WP_024052912.1 | CHAP domain-containing protein | - |
| PUW49_RS00210 (PUW49_00210) | - | 26365..27333 (+) | 969 | WP_024052911.1 | ribose-phosphate diphosphokinase | - |
| PUW49_RS00215 (PUW49_00215) | - | 27488..28675 (+) | 1188 | WP_024052910.1 | pyridoxal phosphate-dependent aminotransferase | - |
| PUW49_RS00220 (PUW49_00220) | recO | 28653..29426 (+) | 774 | WP_024052909.1 | DNA repair protein RecO | - |
| PUW49_RS00225 (PUW49_00225) | plsX | 29423..30421 (+) | 999 | WP_070241458.1 | phosphate acyltransferase PlsX | - |
| PUW49_RS00230 (PUW49_00230) | - | 30418..30663 (+) | 246 | WP_024052907.1 | acyl carrier protein | - |
| PUW49_RS00235 (PUW49_00235) | purC | 30822..31529 (+) | 708 | WP_024052906.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| PUW49_RS00240 (PUW49_00240) | - | 31581..35306 (+) | 3726 | WP_070672486.1 | phosphoribosylformylglycinamidine synthase | - |
| PUW49_RS00245 (PUW49_00245) | purF | 35430..36887 (+) | 1458 | WP_024052904.1 | amidophosphoribosyltransferase | - |
| PUW49_RS00250 (PUW49_00250) | - | 36890..37171 (+) | 282 | WP_024052903.1 | hypothetical protein | - |
| PUW49_RS00255 (PUW49_00255) | purM | 37131..38156 (+) | 1026 | WP_024052902.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| PUW49_RS00260 (PUW49_00260) | purN | 38156..38710 (+) | 555 | WP_024052901.1 | phosphoribosylglycinamide formyltransferase | - |
| PUW49_RS00265 (PUW49_00265) | purH | 38951..40499 (+) | 1549 | Protein_30 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
| PUW49_RS00270 (PUW49_00270) | - | 40558..42492 (-) | 1935 | WP_070241460.1 | GBS Bsp-like repeat-containing protein | - |
Sequence
Protein
Download Length: 157 a.a. Molecular weight: 19266.00 Da Isoelectric Point: 6.2655
>NTDB_id=789634 PUW49_RS00075 WP_024053280.1 14880..15353(+) (comR/comR2) [Streptococcus anginosus strain VSI37]
MEFKELYAKVRGIVLKCRREYYVHLWELSDWEQEGMLVLYQLVSQYPQLVEEESQLYVYYKTKFRNHILDILRKQESQKR
KLNRQAYEEVSEIGHQLSLKELYLDELVILRDQLNSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD
MEFKELYAKVRGIVLKCRREYYVHLWELSDWEQEGMLVLYQLVSQYPQLVEEESQLYVYYKTKFRNHILDILRKQESQKR
KLNRQAYEEVSEIGHQLSLKELYLDELVILRDQLNSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD
Nucleotide
Download Length: 474 bp
>NTDB_id=789634 PUW49_RS00075 WP_024053280.1 14880..15353(+) (comR/comR2) [Streptococcus anginosus strain VSI37]
ATGGAGTTCAAGGAGTTATATGCCAAGGTGAGAGGAATTGTGCTGAAGTGTCGGAGAGAATATTATGTCCACCTGTGGGA
ATTAAGCGATTGGGAACAAGAGGGCATGTTGGTGCTCTATCAGTTGGTAAGCCAGTATCCGCAGCTGGTAGAAGAAGAAA
GTCAGCTCTATGTTTACTATAAGACCAAGTTCCGCAATCATATCCTGGACATCCTTCGTAAACAGGAAAGTCAAAAACGC
AAACTTAATCGTCAAGCTTATGAAGAAGTAAGCGAGATTGGTCACCAGCTCAGCCTAAAAGAACTATATCTGGATGAATT
GGTGATTCTCCGAGACCAACTAAATAGCTATCAAGCTCAACTGAGCCCAGAGAAACAGGAGCAGTATGAGCGCTTACTAG
CCGATGAACGGTTCAAAGGCCGCCAAGCCATGATTCGAGAATTAAGAGCCTACTTAAAAGATTATAGCGATTAA
ATGGAGTTCAAGGAGTTATATGCCAAGGTGAGAGGAATTGTGCTGAAGTGTCGGAGAGAATATTATGTCCACCTGTGGGA
ATTAAGCGATTGGGAACAAGAGGGCATGTTGGTGCTCTATCAGTTGGTAAGCCAGTATCCGCAGCTGGTAGAAGAAGAAA
GTCAGCTCTATGTTTACTATAAGACCAAGTTCCGCAATCATATCCTGGACATCCTTCGTAAACAGGAAAGTCAAAAACGC
AAACTTAATCGTCAAGCTTATGAAGAAGTAAGCGAGATTGGTCACCAGCTCAGCCTAAAAGAACTATATCTGGATGAATT
GGTGATTCTCCGAGACCAACTAAATAGCTATCAAGCTCAACTGAGCCCAGAGAAACAGGAGCAGTATGAGCGCTTACTAG
CCGATGAACGGTTCAAAGGCCGCCAAGCCATGATTCGAGAATTAAGAGCCTACTTAAAAGATTATAGCGATTAA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.