Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   PO908_RS08660 Genome accession   NZ_CP117042
Coordinates   1672279..1672752 (-) Length   157 a.a.
NCBI ID   WP_003026301.1    Uniprot ID   A0AAP6BR36
Organism   Streptococcus anginosus strain CGMH_KH1     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1667279..1677752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PO908_RS08625 (PO908_08590) - 1667370..1668305 (-) 936 WP_021002085.1 IS30 family transposase -
  PO908_RS08630 (PO908_08595) - 1668488..1668856 (-) 369 WP_004224594.1 EXLDI protein -
  PO908_RS08635 (PO908_08600) - 1668993..1669559 (-) 567 WP_004224592.1 NAD(P)H-dependent oxidoreductase -
  PO908_RS08640 (PO908_08605) - 1669556..1670152 (-) 597 WP_003030906.1 TetR/AcrR family transcriptional regulator -
  PO908_RS08645 (PO908_08610) - 1670420..1670788 (-) 369 WP_004224590.1 hypothetical protein -
  PO908_RS08650 (PO908_08615) - 1670796..1671242 (-) 447 WP_003026297.1 LacI family DNA-binding transcriptional regulator -
  PO908_RS08655 (PO908_08620) - 1671268..1672086 (-) 819 WP_003026300.1 Cof-type HAD-IIB family hydrolase -
  PO908_RS08660 (PO908_08625) comR/comR2 1672279..1672752 (-) 474 WP_003026301.1 hypothetical protein Regulator
  PO908_RS08665 (PO908_08630) nusB 1672969..1673394 (-) 426 WP_003026303.1 transcription antitermination factor NusB -
  PO908_RS08670 (PO908_08635) - 1673387..1673776 (-) 390 WP_003026305.1 Asp23/Gls24 family envelope stress response protein -
  PO908_RS08675 (PO908_08640) efp 1673886..1674446 (-) 561 WP_003026309.1 elongation factor P -
  PO908_RS08680 (PO908_08645) - 1674505..1675566 (-) 1062 WP_021002088.1 Xaa-Pro peptidase family protein -
  PO908_RS08685 (PO908_08650) - 1675714..1676469 (+) 756 WP_021002089.1 hypothetical protein -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19289.08 Da        Isoelectric Point: 6.8761

>NTDB_id=782270 PO908_RS08660 WP_003026301.1 1672279..1672752(-) (comR/comR2) [Streptococcus anginosus strain CGMH_KH1]
MEFKELYGKVRGIVLKCRREYYVHLWELSDWDQEGMLVLYQLVSQYPQLVEEDHQLYVYYKTKFRNHILDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDQLKSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide


Download         Length: 474 bp        

>NTDB_id=782270 PO908_RS08660 WP_003026301.1 1672279..1672752(-) (comR/comR2) [Streptococcus anginosus strain CGMH_KH1]
ATGGAGTTCAAGGAGTTATATGGCAAGGTGAGAGGAATTGTGCTGAAGTGTCGGAGGGAATATTATGTCCACCTGTGGGA
GTTAAGTGATTGGGACCAAGAGGGAATGTTGGTGCTCTATCAGTTGGTAAGCCAGTATCCGCAGCTAGTAGAAGAAGATC
ATCAGCTCTATGTTTACTATAAGACCAAGTTCCGCAATCATATTCTGGACATCCTCCGTAAACAGGAAAGTCAAAAACGC
AAACTTGATCGTCAAGCTTATGAAGAAGTGAGCGAGATTGGTCACAAGCTCAGCCTAAAAGAACTATATCTGGATGAATT
GGTGATTCTCCGAGACCAGCTAAAGAGCTATCAAGCTCAACTGAGCCCAGAGAAACAGGAGCAGTACGAACGCTTACTAG
CCGATGAACGGTTCAAAGGCCGCCAAGCTATGATTCGAGAATTAAGAGCCTACTTAAAAGACTATAGTGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

54.545

98.089

0.535
  comX/comX2 Streptococcus pneumoniae Rx1

53.896

98.089

0.529
  comX/comX1 Streptococcus pneumoniae Rx1

53.896

98.089

0.529
  comX/comX2 Streptococcus pneumoniae D39

53.896

98.089

0.529
  comX/comX1 Streptococcus pneumoniae D39

53.896

98.089

0.529
  comX/comX2 Streptococcus pneumoniae R6

53.896

98.089

0.529
  comX/comX1 Streptococcus pneumoniae R6

53.896

98.089

0.529
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

53.896

98.089

0.529
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

53.247

98.089

0.522
  comX/comX2 Streptococcus pneumoniae TIGR4

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae TIGR4

53.247

98.089

0.522
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

53.595

97.452

0.522
  comX/sigX Streptococcus mutans UA159

49.359

99.363

0.49
  comX/sigX Streptococcus suis D9

47.742

98.726

0.471
  comX/sigX Streptococcus suis isolate S10

47.742

98.726

0.471
  comX/sigX Streptococcus suis P1/7

47.742

98.726

0.471
  comX Streptococcus salivarius SK126

45.098

97.452

0.439
  comX Streptococcus thermophilus LMG 18311

44.156

98.089

0.433
  comX Streptococcus thermophilus LMD-9

44.156

98.089

0.433
  comX/sigX Streptococcus salivarius strain HSISS4

44.444

97.452

0.433
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

41.667

99.363

0.414
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

41.667

99.363

0.414
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

41.667

99.363

0.414
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

41.667

99.363

0.414
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

41.667

99.363

0.414
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

41.667

99.363

0.414
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.821

99.363

0.376
  comX Streptococcus sobrinus strain NIDR 6715-7

37.908

97.452

0.369