Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   PFZ59_RS03080 Genome accession   NZ_CP116393
Coordinates   586652..587122 (+) Length   156 a.a.
NCBI ID   WP_024393242.1    Uniprot ID   A0A0M9FMV4
Organism   Streptococcus suis strain SS/UPM/MY/F001     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 585012..596503 586652..587122 within 0


Gene organization within MGE regions


Location: 585012..596503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PFZ59_RS03075 (PFZ59_03075) - 585012..586268 (-) 1257 WP_277697768.1 ISL3 family transposase -
  PFZ59_RS03080 (PFZ59_03080) comX/sigX 586652..587122 (+) 471 WP_024393242.1 sigma-70 family RNA polymerase sigma factor Regulator
  PFZ59_RS03085 (PFZ59_03085) - 587277..588281 (+) 1005 WP_277696681.1 IS5 family transposase -
  PFZ59_RS03090 (PFZ59_03090) - 588417..589931 (+) 1515 WP_277697459.1 flavocytochrome c -
  PFZ59_RS03100 (PFZ59_03100) - 590924..592276 (+) 1353 WP_277697769.1 metallophosphoesterase -
  PFZ59_RS03105 (PFZ59_03105) - 592440..593453 (+) 1014 WP_277697460.1 glycosyltransferase family 2 protein -
  PFZ59_RS03110 (PFZ59_03110) - 593978..595180 (-) 1203 WP_347176383.1 IS110 family transposase -
  PFZ59_RS03115 (PFZ59_03115) - 595499..596503 (+) 1005 WP_277696681.1 IS5 family transposase -

Sequence

Protein


Download         Length: 156 a.a.        Molecular weight: 19116.98 Da        Isoelectric Point: 8.4522

>NTDB_id=777087 PFZ59_RS03080 WP_024393242.1 586652..587122(+) (comX/sigX) [Streptococcus suis strain SS/UPM/MY/F001]
MEFEKVYASVKGIVNKARKEFYIKLWDRDDWEQEGMMTLFELLEDQPWLVDEQVQLYCYFKVKFRNRIKDRIRKQESQKR
KFDRMPHEDIHELSHAIQSPGLINDELLMLRGALRDYRKNLSNDQLDKYEKLISGQCFNGRREMIRDLQIHLKDFR

Nucleotide


Download         Length: 471 bp        

>NTDB_id=777087 PFZ59_RS03080 WP_024393242.1 586652..587122(+) (comX/sigX) [Streptococcus suis strain SS/UPM/MY/F001]
ATGGAATTCGAAAAAGTGTACGCAAGCGTCAAAGGTATTGTAAACAAGGCTCGAAAAGAGTTTTACATTAAACTATGGGA
TCGAGATGATTGGGAACAAGAAGGAATGATGACCTTGTTTGAATTGTTGGAAGATCAACCGTGGCTAGTTGATGAACAAG
TTCAATTATATTGTTATTTCAAAGTCAAGTTCAGAAATCGAATCAAGGATCGTATCCGCAAACAGGAAAGTCAAAAACGC
AAGTTTGACCGTATGCCACATGAAGATATTCACGAATTATCTCACGCAATACAATCACCGGGATTGATAAACGATGAACT
ATTAATGTTGAGAGGTGCCTTGAGAGATTATCGAAAAAATCTGAGCAACGATCAACTTGATAAATACGAAAAATTAATTA
GCGGACAATGTTTTAATGGTCGTCGTGAAATGATACGTGATTTACAAATTCATTTGAAAGACTTTCGCTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FMV4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus suis D9

99.359

100

0.994
  comX/sigX Streptococcus suis isolate S10

98.718

100

0.987
  comX/sigX Streptococcus suis P1/7

98.718

100

0.987
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

49.032

99.359

0.487
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

49.032

99.359

0.487
  comX/comX1 Streptococcus pneumoniae TIGR4

46.358

96.795

0.449
  comX/comX2 Streptococcus pneumoniae TIGR4

46.358

96.795

0.449
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

45.752

98.077

0.449
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

45.098

98.077

0.442
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

45.098

98.077

0.442
  comX/comX1 Streptococcus pneumoniae Rx1

45.695

96.795

0.442
  comX/comX2 Streptococcus pneumoniae D39

45.695

96.795

0.442
  comX/comX1 Streptococcus pneumoniae D39

45.695

96.795

0.442
  comX/comX2 Streptococcus pneumoniae R6

45.695

96.795

0.442
  comX/comX1 Streptococcus pneumoniae R6

45.695

96.795

0.442
  comX/comX2 Streptococcus pneumoniae Rx1

45.695

96.795

0.442
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

44.444

98.077

0.436
  comX/sigX Streptococcus mutans UA159

43.226

99.359

0.429
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

40.645

99.359

0.404
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

40.645

99.359

0.404
  comX Streptococcus sobrinus strain NIDR 6715-7

40.523

98.077

0.397
  comX Streptococcus thermophilus LMG 18311

40.523

98.077

0.397
  comX Streptococcus thermophilus LMD-9

40.523

98.077

0.397
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

99.359

0.397
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

99.359

0.397
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

99.359

0.397
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

99.359

0.397
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.854

100

0.391
  comX Streptococcus salivarius SK126

39.869

98.077

0.391
  comX/sigX Streptococcus salivarius strain HSISS4

39.869

98.077

0.391