Detailed information NTG0069954

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: SA27298_RS01300
• Genome accession: NZ_AP018548
• Coordinates: 256040..256513 (+)
• Length: 157 a.a.
• NCBI ID: WP_003030979.1
• Uniprot ID: A0A3S4MUK8
• Organism: Streptococcus anginosus strain CCUG 27928
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 251040..261513

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA27298_RS01275 (SA27298_0259)	-	252312..253067 (-)	756	WP_003030554.1	hypothetical protein	-
SA27298_RS01280 (SA27298_0260)	-	253226..254287 (+)	1062	WP_003030550.1	Xaa-Pro peptidase family protein	-
SA27298_RS01285 (SA27298_0261)	efp	254346..254906 (+)	561	WP_003026309.1	elongation factor P	-
SA27298_RS01290 (SA27298_0262)	-	255016..255405 (+)	390	WP_003026305.1	Asp23/Gls24 family envelope stress response protein	-
SA27298_RS01295 (SA27298_0263)	nusB	255398..255823 (+)	426	WP_003030524.1	transcription antitermination factor NusB	-
SA27298_RS01300 (SA27298_0264)	comR/comR2	256040..256513 (+)	474	WP_003030979.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 157 a.a.
• Molecular weight: 19347.17 Da
• Isoelectric Point: 7.3491

>NTDB_id=69954 SA27298_RS01300 WP_003030979.1 256040..256513(+) (comR/comR2) [Streptococcus anginosus strain CCUG 27928]
MEFKELYGKVRGIVLKCRREYYVHLWELSDWEQEGMLVLYQLVSRYPQLVEEDHQLYVYYKTKFRNHILDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDQLKSYQSQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide

• Length: 474 bp

>NTDB_id=69954 SA27298_RS01300 WP_003030979.1 256040..256513(+) (comR/comR2) [Streptococcus anginosus strain CCUG 27928]
ATGGAGTTCAAGGAGTTATATGGCAAGGTGAGAGGAATTGTGCTGAAGTGTCGGAGGGAATATTATGTCCACCTGTGGGA
ATTAAGCGATTGGGAACAAGAGGGCATGTTGGTGCTCTATCAGTTGGTGAGTCGCTATCCGCAGCTAGTAGAAGAAGATC
ATCAGCTCTATGTTTACTATAAGACCAAGTTCCGCAATCATATCCTGGACATCCTCCGTAAACAGGAAAGCCAAAAACGC
AAACTCGACCGACAAGCTTATGAAGAAGTGAGCGAGATTGGTCACAAGCTCAGCCTGAAAGAGTTGTATCTGGATGAACT
GGTGATTCTCCGGGACCAGCTAAAGAGTTACCAATCTCAACTGAGTCCAGAGAAACAAGAACAGTACGAGCGCTTACTAG
CCGACGAACGGTTCAAAGGCCGCCAAGCGATGATTCGAGAATTAAGAGCCTACTTAAAAGACTATAGCGATTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A3S4MUK8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	60.897	99.363	0.605
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	60.897	99.363	0.605
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	54.545	98.089	0.535
comX/comX2	Streptococcus pneumoniae TIGR4	54.545	98.089	0.535
comX/comX1	Streptococcus pneumoniae TIGR4	54.545	98.089	0.535
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	54.545	98.089	0.535
comX/comX2	Streptococcus pneumoniae D39	53.896	98.089	0.529
comX/comX2	Streptococcus pneumoniae Rx1	53.896	98.089	0.529
comX/comX1	Streptococcus pneumoniae Rx1	53.896	98.089	0.529
comX/comX1	Streptococcus pneumoniae D39	53.896	98.089	0.529
comX/comX2	Streptococcus pneumoniae R6	53.896	98.089	0.529
comX/comX1	Streptococcus pneumoniae R6	53.896	98.089	0.529
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	53.247	98.089	0.522
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	53.247	98.089	0.522
comX/sigX	Streptococcus mutans UA159	49.359	99.363	0.49
comX/sigX	Streptococcus suis D9	48.387	98.726	0.478
comX/sigX	Streptococcus suis isolate S10	48.387	98.726	0.478
comX/sigX	Streptococcus suis P1/7	48.387	98.726	0.478
comX	Streptococcus salivarius SK126	45.455	98.089	0.446
comX/sigX	Streptococcus salivarius strain HSISS4	44.805	98.089	0.439
comX	Streptococcus thermophilus LMG 18311	44.805	98.089	0.439
comX	Streptococcus thermophilus LMD-9	44.805	98.089	0.439
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.308	99.363	0.42
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.308	99.363	0.42
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42.308	99.363	0.42
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42.308	99.363	0.42
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.308	99.363	0.42
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.308	99.363	0.42
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	37.821	99.363	0.376
comX	Streptococcus sobrinus strain NIDR 6715-7	38.562	97.452	0.376