Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   STO1_RS08650 Genome accession   NZ_AP018338
Coordinates   1693010..1693483 (-) Length   157 a.a.
NCBI ID   WP_007522820.1    Uniprot ID   A0A224A8E4
Organism   Streptococcus oralis subsp. tigurinus strain osk_001     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1688010..1698483
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STO1_RS08650 (STO1_016460) comX/comX2 1693010..1693483 (-) 474 WP_007522820.1 hypothetical protein Regulator
  STO1_RS08655 (STO1_016470) nusG 1693604..1694140 (-) 537 WP_000376728.1 transcription termination/antitermination protein NusG -
  STO1_RS08660 (STO1_016480) secE 1694192..1694368 (-) 177 WP_000505776.1 preprotein translocase subunit SecE -
  STO1_RS08665 (STO1_016490) rpmG 1694378..1694530 (-) 153 WP_009755504.1 50S ribosomal protein L33 -
  STO1_RS08670 (STO1_016500) pbp2a 1694583..1696778 (-) 2196 WP_096422836.1 penicillin-binding protein PBP2A -
  STO1_RS08675 (STO1_016510) - 1696865..1697740 (+) 876 WP_084647669.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19319.22 Da        Isoelectric Point: 8.2582

>NTDB_id=69084 STO1_RS08650 WP_007522820.1 1693010..1693483(-) (comX/comX2) [Streptococcus oralis subsp. tigurinus strain osk_001]
MKLKDLYEESKGIVHKCRKDYHLHLWEKEDWDQEGMLCLYELVSRNPELLEGERHQLYVCFKTKFRNRILDYIRKQESHK
RRFDKEPYEEVSEISHRLGEKGLRLDDYYLFHELLKNYKSKQSMEKQELIDRLMGGEVFRGRKALLRELSLIFSEFR

Nucleotide


Download         Length: 474 bp        

>NTDB_id=69084 STO1_RS08650 WP_007522820.1 1693010..1693483(-) (comX/comX2) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGAAGCTAAAAGACTTATATGAAGAAAGTAAGGGAATCGTCCATAAGTGTCGCAAAGATTATCATTTGCATCTGTGGGA
GAAAGAGGACTGGGACCAGGAAGGCATGTTATGTCTGTATGAGCTGGTGAGTCGCAATCCAGAGTTGCTAGAGGGCGAGC
GCCATCAACTATATGTTTGCTTTAAAACAAAATTTAGAAATCGTATTCTAGATTACATCCGTAAACAGGAAAGCCACAAG
CGCCGTTTTGACAAAGAACCCTATGAAGAGGTGAGTGAGATTAGCCATCGTCTAGGAGAAAAAGGACTCAGGCTGGACGA
TTATTATCTCTTTCACGAACTTCTAAAGAATTACAAATCAAAGCAGAGTATGGAAAAACAAGAATTAATAGATCGTCTCA
TGGGAGGAGAAGTCTTTAGAGGACGTAAAGCTCTCCTGAGAGAACTTTCCCTTATATTTTCAGAATTTCGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A224A8E4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

64.286

98.089

0.631
  comX/comX2 Streptococcus pneumoniae D39

64.286

98.089

0.631
  comX/comX1 Streptococcus pneumoniae D39

64.286

98.089

0.631
  comX/comX2 Streptococcus pneumoniae R6

64.286

98.089

0.631
  comX/comX1 Streptococcus pneumoniae R6

64.286

98.089

0.631
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

64.286

98.089

0.631
  comX/comX1 Streptococcus pneumoniae Rx1

64.286

98.089

0.631
  comX/comX1 Streptococcus pneumoniae TIGR4

63.636

98.089

0.624
  comX/comX2 Streptococcus pneumoniae TIGR4

63.636

98.089

0.624
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

62.987

98.089

0.618
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

62.987

98.089

0.618
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

62.987

98.089

0.618
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comX/sigX Streptococcus mutans UA159

46.711

96.815

0.452
  comX/sigX Streptococcus suis isolate S10

41.401

100

0.414
  comX/sigX Streptococcus suis D9

41.401

100

0.414
  comX/sigX Streptococcus suis P1/7

41.401

100

0.414
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.744

99.363

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.744

99.363

0.395
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

39.744

99.363

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

39.744

99.363

0.395
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

39.744

99.363

0.395
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

39.744

99.363

0.395
  comX Streptococcus sobrinus strain NIDR 6715-7

42.657

91.083

0.389
  comX Streptococcus thermophilus LMG 18311

40

95.541

0.382
  comX Streptococcus thermophilus LMD-9

40

95.541

0.382
  comX Streptococcus salivarius SK126

40

95.541

0.382
  comX/sigX Streptococcus salivarius strain HSISS4

40

95.541

0.382
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.342

100

0.376

Multiple sequence alignment