Detailed information    

insolico Bioinformatically predicted

Overview


Name   comX/comX2   Type   Regulator
Locus tag   MP387_RS00950 Genome accession   NZ_CP094226
Coordinates   185105..185578 (+) Length   157 a.a.
NCBI ID   WP_242747020.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context


Location: 180105..190578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS00925 (MP387_00925) - 180842..181717 (-) 876 WP_341275347.1 RluA family pseudouridine synthase -
  MP387_RS00930 (MP387_00930) pbp2a 181804..183999 (+) 2196 WP_242747001.1 penicillin-binding protein PBP2A -
  MP387_RS00935 (MP387_00935) rpmG 184052..184204 (+) 153 WP_001809375.1 50S ribosomal protein L33 -
  MP387_RS00940 (MP387_00940) secE 184214..184390 (+) 177 WP_000505776.1 preprotein translocase subunit SecE -
  MP387_RS00945 (MP387_00945) nusG 184448..184984 (+) 537 WP_242747017.1 transcription termination/antitermination protein NusG -
  MP387_RS00950 (MP387_00950) comX/comX2 185105..185578 (+) 474 WP_242747020.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence


Protein


Download         Length: 157 a.a.        Molecular weight: 19274.12 Da        Isoelectric Point: 7.8480

>NTDB_id=668083 MP387_RS00950 WP_242747020.1 185105..185578(+) (comX/comX2) [Streptococcus oralis strain 1648]
MNLKDLYEESKGIVHKCRKDYHLHLWEKEDWDQEGMLCLYELVSRNPELLEGERHQLYVCFKTKFRNRILDYIRKQESHK
RRFDKEPYEEVSEISHRLGEKGLRLDDYYLFHELLKTYKSKQSMEKQELIDRLIGGEVFRGRKALLRELSLIFSEFR

Nucleotide


Download         Length: 474 bp        

>NTDB_id=668083 MP387_RS00950 WP_242747020.1 185105..185578(+) (comX/comX2) [Streptococcus oralis strain 1648]
ATGAATCTAAAAGACTTATATGAAGAAAGTAAGGGAATCGTCCATAAGTGTCGAAAAGATTATCATTTGCATCTGTGGGA
GAAAGAGGACTGGGACCAGGAAGGCATGTTATGTCTATATGAGCTGGTGAGTCGCAACCCAGAGTTACTAGAGGGCGAGC
GCCATCAACTTTATGTTTGCTTTAAAACAAAATTTAGAAATCGTATTCTAGATTACATCCGTAAGCAGGAAAGCCACAAG
CGTCGTTTCGACAAAGAACCCTATGAAGAAGTGAGTGAGATTAGCCATCGTCTAGGAGAAAAAGGACTCAGGCTGGACGA
TTATTATCTCTTTCACGAACTTCTGAAGACATACAAATCAAAGCAGAGTATGGAAAAACAAGAATTAATAGATCGTCTAA
TAGGAGGAGAAGTCTTTAGAGGACGTAAAGCTCTACTAAGAGAACTTTCCCTAATCTTTTCAGAATTTCGGTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

64.286

98.089

0.631

  comX/comX2 Streptococcus pneumoniae D39

64.286

98.089

0.631

  comX/comX1 Streptococcus pneumoniae D39

64.286

98.089

0.631

  comX/comX2 Streptococcus pneumoniae R6

64.286

98.089

0.631

  comX/comX1 Streptococcus pneumoniae R6

64.286

98.089

0.631

  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

64.286

98.089

0.631

  comX/comX1 Streptococcus pneumoniae Rx1

64.286

98.089

0.631

  comX/comX1 Streptococcus pneumoniae TIGR4

63.636

98.089

0.624

  comX/comX2 Streptococcus pneumoniae TIGR4

63.636

98.089

0.624

  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

62.987

98.089

0.618

  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

62.987

98.089

0.618

  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

62.987

98.089

0.618

  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

52.564

99.363

0.522

  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

52.564

99.363

0.522

  comX/sigX Streptococcus mutans UA159

46.711

96.815

0.452

  comX/sigX Streptococcus suis isolate S10

42.038

100

0.42

  comX/sigX Streptococcus suis D9

42.038

100

0.42

  comX/sigX Streptococcus suis P1/7

42.038

100

0.42

  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

40.385

99.363

0.401

  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

40.385

99.363

0.401

  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42

95.541

0.401

  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42

95.541

0.401

  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42

95.541

0.401

  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42

95.541

0.401

  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.975

100

0.382

  comX/sigX Streptococcus salivarius strain HSISS4

40

95.541

0.382

  comX Streptococcus thermophilus LMG 18311

40

95.541

0.382

  comX Streptococcus thermophilus LMD-9

40

95.541

0.382

  comX Streptococcus salivarius SK126

40

95.541

0.382

  comX Streptococcus sobrinus strain NIDR 6715-7

41.958

91.083

0.382


Multiple sequence alignment