Detailed information NTG0066595

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: SCSC_RS08485
• Genome accession: NZ_AP014647
• Coordinates: 1724600..1725082 (-)
• Length: 160 a.a.
• NCBI ID: WP_037598771.1
• Uniprot ID: -
• Organism: Streptococcus constellatus subsp. constellatus strain CCUG 24889
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1716665..1725082	1724600..1725082	within	0

Gene organization within MGE regions

Location: 1716665..1725082

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCSC_RS08395	-	1717321..1717689 (+)	369	Protein_1634	type II toxin-antitoxin system RelE/ParE family toxin	-
SCSC_RS08400 (SCSC_1731)	-	1717676..1717951 (+)	276	WP_006270606.1	helix-turn-helix transcriptional regulator	-
SCSC_RS08485 (SCSC_1750)	comR/comR2	1724600..1725082 (-)	483	WP_037598771.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 160 a.a.
• Molecular weight: 19753.61 Da
• Isoelectric Point: 8.6079

>NTDB_id=66595 SCSC_RS08485 WP_037598771.1 1724600..1725082(-) (comR/comR2) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
MDFKELYDKVRGIVLKCRREYYVHLWELSDWDQEGMLVLYELVSRYPQLVESESRLYVYYKTKFRNHIKDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRAQLKSYQKQLSPEKQEQYERLLADERFQGRQAMLRELRAYLQDYDERKS

Nucleotide

• Length: 483 bp

>NTDB_id=66595 SCSC_RS08485 WP_037598771.1 1724600..1725082(-) (comR/comR2) [Streptococcus constellatus subsp. constellatus strain CCUG 24889]
ATGGACTTCAAGGAGTTGTATGACAAAGTGAGAGGGATCGTACTGAAGTGTCGCCGGGAATATTATGTCCACCTGTGGGA
GTTAAGTGATTGGGACCAAGAAGGGATGCTGGTCTTATATGAGTTGGTGAGTCGCTATCCGCAACTGGTAGAGTCAGAAA
GTCGTCTCTATGTTTACTATAAGACCAAGTTCCGTAATCACATCAAGGACATCCTGCGCAAACAAGAAAGCCAAAAGCGC
AAACTAGACCGTCAAGCTTATGAGGAAGTGAGCGAGATAGGTCACAAGCTCAGCCTGAAAGAACTCTATTTGGATGAATT
GGTGATTCTCCGAGCCCAACTAAAGAGCTATCAAAAGCAGCTAAGTCCAGAGAAACAAGAACAGTATGAGCGCTTACTAG
CAGATGAACGGTTTCAAGGACGCCAAGCGATGCTTCGGGAGTTACGGGCCTACTTACAAGATTACGATGAAAGAAAAAGC
TAG

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	61.392	98.75	0.606
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	61.392	98.75	0.606
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	56.41	97.5	0.55
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	55.769	97.5	0.544
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	55.128	97.5	0.537
comX/comX1	Streptococcus pneumoniae R6	55.556	95.625	0.531
comX/comX1	Streptococcus pneumoniae D39	55.556	95.625	0.531
comX/comX2	Streptococcus pneumoniae Rx1	55.556	95.625	0.531
comX/comX1	Streptococcus pneumoniae Rx1	55.556	95.625	0.531
comX/comX2	Streptococcus pneumoniae D39	55.556	95.625	0.531
comX/comX2	Streptococcus pneumoniae R6	55.556	95.625	0.531
comX/comX2	Streptococcus pneumoniae TIGR4	54.487	97.5	0.531
comX/comX1	Streptococcus pneumoniae TIGR4	54.487	97.5	0.531
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	54.487	97.5	0.531
comX/sigX	Streptococcus mutans UA159	49.682	98.125	0.488
comX/sigX	Streptococcus suis D9	46.452	96.875	0.45
comX/sigX	Streptococcus suis isolate S10	46.452	96.875	0.45
comX/sigX	Streptococcus suis P1/7	46.452	96.875	0.45
comX	Streptococcus salivarius SK126	43.506	96.25	0.419
comX/sigX	Streptococcus salivarius strain HSISS4	42.857	96.25	0.412
comX	Streptococcus thermophilus LMG 18311	42.857	96.25	0.412
comX	Streptococcus thermophilus LMD-9	42.857	96.25	0.412
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	41.401	98.125	0.406
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	41.401	98.125	0.406
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	41.401	98.125	0.406
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	41.401	98.125	0.406
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	41.401	98.125	0.406
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	41.401	98.125	0.406
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.103	97.5	0.381
comX	Streptococcus sobrinus strain NIDR 6715-7	37.419	96.875	0.362