Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   SANR_RS10035 Genome accession   NC_022239
Coordinates   2069105..2069578 (-) Length   157 a.a.
NCBI ID   WP_020999414.1    Uniprot ID   -
Organism   Streptococcus anginosus C238     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2064105..2074578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SANR_RS10015 (SANR_1947) - 2065807..2066268 (-) 462 WP_003036579.1 CtsR family transcriptional regulator -
  SANR_RS10020 (SANR_1948) - 2066527..2066877 (+) 351 WP_003036598.1 hypothetical protein -
  SANR_RS10025 (SANR_1949) tsf 2066964..2068007 (-) 1044 WP_003026508.1 translation elongation factor Ts -
  SANR_RS10030 (SANR_1950) rpsB 2068090..2068872 (-) 783 WP_003036542.1 30S ribosomal protein S2 -
  SANR_RS10035 (SANR_1951) comR/comR2 2069105..2069578 (-) 474 WP_020999414.1 sigma-70 family RNA polymerase sigma factor Regulator
  SANR_RS10040 (SANR_1952) rplQ 2070005..2070391 (-) 387 WP_003026513.1 50S ribosomal protein L17 -
  SANR_RS10045 (SANR_1953) - 2070403..2071341 (-) 939 WP_003026514.1 DNA-directed RNA polymerase subunit alpha -
  SANR_RS10050 (SANR_1954) rpsK 2071386..2071769 (-) 384 WP_001118385.1 30S ribosomal protein S11 -
  SANR_RS10055 (SANR_1955) rpsM 2071789..2072154 (-) 366 WP_002262317.1 30S ribosomal protein S13 -
  SANR_RS11315 (SANR_1956) rpmJ 2072170..2072286 (-) 117 WP_001808836.1 50S ribosomal protein L36 -
  SANR_RS10060 (SANR_1957) infA 2072311..2072529 (-) 219 WP_001029883.1 translation initiation factor IF-1 -
  SANR_RS10065 (SANR_1958) - 2072645..2073283 (-) 639 WP_003034799.1 adenylate kinase -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19214.03 Da        Isoelectric Point: 6.2636

>NTDB_id=61693 SANR_RS10035 WP_020999414.1 2069105..2069578(-) (comR/comR2) [Streptococcus anginosus C238]
MEFKELYAKVRGIVLKCCREYYVHLWELSDWDQEGMLVLYQLVSQYPQLVEEESQLYVYYKTKFRNHILDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDQLKSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide


Download         Length: 474 bp        

>NTDB_id=61693 SANR_RS10035 WP_020999414.1 2069105..2069578(-) (comR/comR2) [Streptococcus anginosus C238]
ATGGAGTTCAAGGAGTTATATGCCAAGGTGAGAGGAATTGTACTAAAGTGCTGTCGGGAATATTATGTCCACCTGTGGGA
GTTAAGTGATTGGGACCAAGAGGGAATGTTGGTGCTCTATCAGTTGGTAAGCCAGTATCCGCAGCTGGTAGAAGAAGAAA
GTCAGCTCTATGTTTACTATAAGACCAAGTTCCGGAATCATATCCTGGACATCCTCCGTAAACAGGAAAGTCAAAAACGC
AAACTTGATCGTCAAGCTTATGAAGAAGTGAGCGAGATTGGTCACAAGCTCAGCCTAAAAGAACTATATCTGGATGAATT
GGTGATTCTCCGAGACCAGCTAAAGAGCTATCAAGCTCAACTGAGCCCAGAGAAACAGGAGCAGTACGAGCGCTTACTAG
CCGATGAACGGTTCAAAGGCCGCCAAGCTATGATTCGAGAATTAAGAGCCTACTTAAAAGATTATAGTGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

53.896

98.089

0.529
  comX/comX2 Streptococcus pneumoniae Rx1

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae Rx1

53.247

98.089

0.522
  comX/comX2 Streptococcus pneumoniae D39

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae D39

53.247

98.089

0.522
  comX/comX2 Streptococcus pneumoniae R6

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae R6

53.247

98.089

0.522
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

53.247

98.089

0.522
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

52.597

98.089

0.516
  comX/comX2 Streptococcus pneumoniae TIGR4

52.597

98.089

0.516
  comX/comX1 Streptococcus pneumoniae TIGR4

52.597

98.089

0.516
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

52.597

98.089

0.516
  comX/sigX Streptococcus mutans UA159

48.718

99.363

0.484
  comX/sigX Streptococcus suis D9

47.742

98.726

0.471
  comX/sigX Streptococcus suis isolate S10

47.742

98.726

0.471
  comX/sigX Streptococcus suis P1/7

47.742

98.726

0.471
  comX Streptococcus salivarius SK126

44.156

98.089

0.433
  comX/sigX Streptococcus salivarius strain HSISS4

43.506

98.089

0.427
  comX Streptococcus thermophilus LMG 18311

43.506

98.089

0.427
  comX Streptococcus thermophilus LMD-9

43.506

98.089

0.427
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.308

99.363

0.42
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

42.308

99.363

0.42
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.308

99.363

0.42
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.821

99.363

0.376
  comX Streptococcus sobrinus strain NIDR 6715-7

38.562

97.452

0.376

Multiple sequence alignment