Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   SANR_RS09175 Genome accession   NC_022239
Coordinates   1884519..1884992 (-) Length   157 a.a.
NCBI ID   WP_020999816.1    Uniprot ID   -
Organism   Streptococcus anginosus C238     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1879519..1889992
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SANR_RS09145 (SANR_1774) - 1879545..1880480 (-) 936 WP_003037748.1 IS30 family transposase -
  SANR_RS12190 - 1880663..1881033 (-) 371 Protein_1799 EXLDI protein -
  SANR_RS09155 (SANR_1775) - 1881167..1881733 (-) 567 WP_003037712.1 NAD(P)H-dependent oxidoreductase -
  SANR_RS09160 (SANR_1776) - 1881730..1882326 (-) 597 WP_003037776.1 TetR/AcrR family transcriptional regulator -
  SANR_RS12025 - 1882594..1883058 (-) 465 WP_003037706.1 hypothetical protein -
  SANR_RS12030 - 1883059..1883322 (-) 264 WP_003037714.1 catabolite control protein B family protein -
  SANR_RS12035 - 1883253..1883519 (-) 267 WP_327082761.1 LacI family DNA-binding transcriptional regulator -
  SANR_RS09170 (SANR_1778) - 1883586..1884303 (-) 718 Protein_1805 HAD family hydrolase -
  SANR_RS09175 (SANR_1779) comR/comR2 1884519..1884992 (-) 474 WP_020999816.1 sigma-70 family RNA polymerase sigma factor Regulator
  SANR_RS09180 (SANR_1780) nusB 1885209..1885634 (-) 426 WP_003037723.1 transcription antitermination factor NusB -
  SANR_RS09185 (SANR_1781) - 1885627..1886016 (-) 390 WP_003037725.1 Asp23/Gls24 family envelope stress response protein -
  SANR_RS09190 (SANR_1782) efp 1886127..1886687 (-) 561 WP_003037772.1 elongation factor P -
  SANR_RS09195 (SANR_1783) - 1886746..1887807 (-) 1062 WP_020999817.1 M24 family metallopeptidase -
  SANR_RS09200 (SANR_1784) - 1887966..1888721 (+) 756 WP_020999818.1 hypothetical protein -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19278.12 Da        Isoelectric Point: 6.8671

>NTDB_id=61689 SANR_RS09175 WP_020999816.1 1884519..1884992(-) (comR/comR2) [Streptococcus anginosus C238]
MEFKELYGKVRGIVLKCRREYYVHLWELSDWEQEGMLVLYQLVSRYPQLVEEDHQLYVYYKTKFRNHILDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDQLKSYQAQLSPEKQEQYECLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide


Download         Length: 474 bp        

>NTDB_id=61689 SANR_RS09175 WP_020999816.1 1884519..1884992(-) (comR/comR2) [Streptococcus anginosus C238]
ATGGAGTTCAAGGAGTTATATGGCAAGGTAAGAGGAATTGTGCTGAAGTGTCGGAGGGAATATTATGTCCACCTGTGGGA
ATTAAGCGATTGGGAACAAGAGGGGATGTTGGTGCTCTATCAGTTGGTGAGTCGCTATCCGCAGCTAGTAGAAGAAGATC
ATCAGCTCTATGTTTACTATAAGACCAAGTTCCGCAATCATATCCTAGACATCCTCCGTAAACAGGAAAGTCAAAAACGC
AAACTTGATCGTCAAGCTTATGAAGAAGTGAGCGAGATTGGTCACAAGCTCAGCCTAAAAGAACTATATCTGGATGAATT
GGTGATTCTCCGAGACCAGCTAAAGAGCTATCAAGCTCAACTGAGTCCAGAGAAACAAGAGCAGTATGAGTGCTTACTAG
CCGATGAACGGTTCAAGGGTCGCCAAGCGATGATTCGAGAATTAAGAGCCTACTTAAAAGACTATAGCGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

59.615

99.363

0.592
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

59.615

99.363

0.592
  comX/comX2 Streptococcus pneumoniae TIGR4

53.896

98.089

0.529
  comX/comX1 Streptococcus pneumoniae TIGR4

53.896

98.089

0.529
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

53.896

98.089

0.529
  comX/comX2 Streptococcus pneumoniae Rx1

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae Rx1

53.247

98.089

0.522
  comX/comX2 Streptococcus pneumoniae D39

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae D39

53.247

98.089

0.522
  comX/comX2 Streptococcus pneumoniae R6

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae R6

53.247

98.089

0.522
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

53.247

98.089

0.522
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

52.597

98.089

0.516
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

51.948

98.089

0.51
  comX/sigX Streptococcus mutans UA159

48.718

99.363

0.484
  comX/sigX Streptococcus suis D9

48.387

98.726

0.478
  comX/sigX Streptococcus suis isolate S10

48.387

98.726

0.478
  comX/sigX Streptococcus suis P1/7

48.387

98.726

0.478
  comX Streptococcus salivarius SK126

44.805

98.089

0.439
  comX/sigX Streptococcus salivarius strain HSISS4

44.156

98.089

0.433
  comX Streptococcus thermophilus LMG 18311

44.156

98.089

0.433
  comX Streptococcus thermophilus LMD-9

44.156

98.089

0.433
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.308

99.363

0.42
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

42.308

99.363

0.42
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.308

99.363

0.42
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.821

99.363

0.376
  comX Streptococcus sobrinus strain NIDR 6715-7

38.562

97.452

0.376

Multiple sequence alignment