Detailed information NTG0054181

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: A20_RS01455
• Genome accession: NC_018936
• Coordinates: 270397..270855 (+)
• Length: 152 a.a.
• NCBI ID: WP_015055913.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes A20
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	271466..272588	270397..270855	flank	611

Gene organization within MGE regions

Location: 270397..272588

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A20_RS01455 (A20_0307)	comX/sigX/comX2/sigX2	270397..270855 (+)	459	WP_015055913.1	hypothetical protein	Regulator
A20_RS09285	-	271466..272588 (+)	1123	Protein_237	ISAs1-like element IS1548 family transposase	-

Sequence

Protein

• Length: 152 a.a.
• Molecular weight: 18664.59 Da
• Isoelectric Point: 9.7374

>NTDB_id=54181 A20_RS01455 WP_015055913.1 270397..270855(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes A20]
MKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYLKDLLRRQESQKRQFHKLAY
EEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGERFKGRRALLRKISPYFKEFAQQL

Nucleotide

• Length: 459 bp

>NTDB_id=54181 A20_RS01455 WP_015055913.1 270397..270855(+) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes A20]
TTGAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATGACTGGTTACAAGA
AGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTATATCGCTATTTTA
AAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCATAAGTTAGCATAT
GAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTTATCAAGAGGTAAT
AGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAACGTTTCAAGGGAA
GACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	100	99.342	0.993
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	100	99.342	0.993
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	100	99.342	0.993
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	100	99.342	0.993
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	99.338	99.342	0.987
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	99.338	99.342	0.987
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	49.66	96.711	0.48
comX	Streptococcus sobrinus strain NIDR 6715-7	46	98.684	0.454
comX/sigX	Streptococcus mutans UA159	44.667	98.684	0.441
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	43.537	96.711	0.421
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	41.06	99.342	0.408
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	41.06	99.342	0.408
comX	Streptococcus salivarius SK126	42.466	96.053	0.408
comX/sigX	Streptococcus salivarius strain HSISS4	42.466	96.053	0.408
comX	Streptococcus thermophilus LMD-9	42.177	96.711	0.408
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	42.177	96.711	0.408
comX	Streptococcus thermophilus LMG 18311	42.177	96.711	0.408
comX/sigX	Streptococcus suis isolate S10	41.781	96.053	0.401
comX/sigX	Streptococcus suis D9	41.781	96.053	0.401
comX/sigX	Streptococcus suis P1/7	41.781	96.053	0.401
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	41.781	96.053	0.401
comX/comX2	Streptococcus pneumoniae D39	39.865	97.368	0.388
comX/comX1	Streptococcus pneumoniae D39	39.865	97.368	0.388
comX/comX2	Streptococcus pneumoniae R6	39.865	97.368	0.388
comX/comX1	Streptococcus pneumoniae R6	39.865	97.368	0.388
comX/comX1	Streptococcus pneumoniae Rx1	39.865	97.368	0.388
comX/comX2	Streptococcus pneumoniae TIGR4	39.865	97.368	0.388
comX/comX1	Streptococcus pneumoniae TIGR4	39.865	97.368	0.388
comX/comX2	Streptococcus pneumoniae Rx1	39.865	97.368	0.388
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	40.136	96.711	0.388