Detailed information NTG0053950

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: GGS_RS01860
• Genome accession: NC_018712
• Coordinates: 364395..364853 (+)
• Length: 152 a.a.
• NCBI ID: WP_015016684.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis RE378
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	365393..365979	364395..364853	flank	540

Gene organization within MGE regions

Location: 364395..365979

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GGS_RS01860 (GGS_0354)	comX/sigX/comX2/sigX2	364395..364853 (+)	459	WP_015016684.1	hypothetical protein	Regulator
GGS_RS01865	-	365052..365979 (-)	928	Protein_327	IS30 family transposase	-

Sequence

Protein

• Length: 152 a.a.
• Molecular weight: 18092.83 Da
• Isoelectric Point: 9.6107

>NTDB_id=53950 GGS_RS01860 WP_015016684.1 364395..364853(+) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae subsp. equisimilis RE378]
MSKVKPIILKLKRHYYLQLWETDDWLQEGHLVLVKLLERHPELVGDEARLYRYFKTKFSSYLKDVLRRQESQKRQFDKMA
YEEIGDVAHAIPAGGLWLDDYVAYREVLVQVEEALSEADRKQFQALVRGERFKGRQALLRKVRPYFSGFDQG

Nucleotide

• Length: 459 bp

>NTDB_id=53950 GGS_RS01860 WP_015016684.1 364395..364853(+) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae subsp. equisimilis RE378]
TTGAGCAAGGTCAAACCTATTATTTTAAAGCTGAAGCGTCATTATTACTTACAGTTGTGGGAGACGGATGACTGGTTACA
AGAGGGGCATTTGGTTTTAGTGAAGTTGTTGGAACGTCACCCAGAGTTAGTAGGAGATGAGGCTCGCTTGTATCGGTATT
TTAAAACCAAGTTTTCGTCGTATTTGAAAGATGTCTTGCGTCGGCAAGAAAGTCAGAAACGCCAGTTTGACAAGATGGCT
TATGAGGAGATAGGGGATGTGGCGCATGCGATTCCAGCTGGCGGGTTATGGTTGGATGATTATGTGGCCTATCGGGAGGT
TTTAGTACAAGTGGAGGAGGCCTTAAGCGAAGCGGATCGGAAGCAGTTTCAGGCCTTAGTGAGAGGGGAACGGTTCAAGG
GGCGTCAGGCTTTGCTTAGGAAGGTTCGTCCTTACTTTAGTGGGTTTGACCAAGGGTGA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	75.168	98.026	0.737
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	75.168	98.026	0.737
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	75.168	98.026	0.737
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	75.168	98.026	0.737
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	74.497	98.026	0.73
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	74.497	98.026	0.73
comX/sigX	Streptococcus mutans UA159	48.667	98.684	0.48
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	48.98	96.711	0.474
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	47.297	97.368	0.461
comX	Streptococcus sobrinus strain NIDR 6715-7	44.667	98.684	0.441
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	44.966	98.026	0.441
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	44.595	97.368	0.434
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	44.595	97.368	0.434
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	44.595	97.368	0.434
comX/comX2	Streptococcus pneumoniae Rx1	44.898	96.711	0.434
comX/comX2	Streptococcus pneumoniae TIGR4	44.898	96.711	0.434
comX/comX1	Streptococcus pneumoniae TIGR4	44.898	96.711	0.434
comX/comX1	Streptococcus pneumoniae Rx1	44.898	96.711	0.434
comX/comX2	Streptococcus pneumoniae D39	44.898	96.711	0.434
comX/comX1	Streptococcus pneumoniae D39	44.898	96.711	0.434
comX/comX2	Streptococcus pneumoniae R6	44.898	96.711	0.434
comX/comX1	Streptococcus pneumoniae R6	44.898	96.711	0.434
comX	Streptococcus thermophilus LMG 18311	43.919	97.368	0.428
comX	Streptococcus thermophilus LMD-9	43.919	97.368	0.428
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	42.953	98.026	0.421
comX	Streptococcus salivarius SK126	42.177	96.711	0.408
comX/sigX	Streptococcus salivarius strain HSISS4	42.177	96.711	0.408
comX/sigX	Streptococcus suis P1/7	39.189	97.368	0.382
comX/sigX	Streptococcus suis D9	39.189	97.368	0.382
comX/sigX	Streptococcus suis isolate S10	39.189	97.368	0.382