Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   I6J13_RS06155 Genome accession   NZ_CP068213
Coordinates   1266023..1266505 (-) Length   160 a.a.
NCBI ID   WP_037598771.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1156     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1258088..1266505 1266023..1266505 within 0


Gene organization within MGE regions


Location: 1258088..1266505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J13_RS06065 (I6J13_06065) - 1258744..1259112 (+) 369 Protein_1207 type II toxin-antitoxin system RelE/ParE family toxin -
  I6J13_RS06070 (I6J13_06070) - 1259099..1259374 (+) 276 WP_006270606.1 helix-turn-helix transcriptional regulator -
  I6J13_RS06155 (I6J13_06155) comR/comR2 1266023..1266505 (-) 483 WP_037598771.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 19753.61 Da        Isoelectric Point: 8.6079

>NTDB_id=528056 I6J13_RS06155 WP_037598771.1 1266023..1266505(-) (comR/comR2) [Streptococcus constellatus strain FDAARGOS_1156]
MDFKELYDKVRGIVLKCRREYYVHLWELSDWDQEGMLVLYELVSRYPQLVESESRLYVYYKTKFRNHIKDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRAQLKSYQKQLSPEKQEQYERLLADERFQGRQAMLRELRAYLQDYDERKS

Nucleotide


Download         Length: 483 bp        

>NTDB_id=528056 I6J13_RS06155 WP_037598771.1 1266023..1266505(-) (comR/comR2) [Streptococcus constellatus strain FDAARGOS_1156]
ATGGACTTCAAGGAGTTGTATGACAAAGTGAGAGGGATCGTACTGAAGTGTCGCCGGGAATATTATGTCCACCTGTGGGA
GTTAAGTGATTGGGACCAAGAAGGGATGCTGGTCTTATATGAGTTGGTGAGTCGCTATCCGCAACTGGTAGAGTCAGAAA
GTCGTCTCTATGTTTACTATAAGACCAAGTTCCGTAATCACATCAAGGACATCCTGCGCAAACAAGAAAGCCAAAAGCGC
AAACTAGACCGTCAAGCTTATGAGGAAGTGAGCGAGATAGGTCACAAGCTCAGCCTGAAAGAACTCTATTTGGATGAATT
GGTGATTCTCCGAGCCCAACTAAAGAGCTATCAAAAGCAGCTAAGTCCAGAGAAACAAGAACAGTATGAGCGCTTACTAG
CAGATGAACGGTTTCAAGGACGCCAAGCGATGCTTCGGGAGTTACGGGCCTACTTACAAGATTACGATGAAAGAAAAAGC
TAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

61.392

98.75

0.606
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

61.392

98.75

0.606
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

56.41

97.5

0.55
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

55.769

97.5

0.544
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

55.128

97.5

0.537
  comX/comX1 Streptococcus pneumoniae R6

55.556

95.625

0.531
  comX/comX1 Streptococcus pneumoniae D39

55.556

95.625

0.531
  comX/comX2 Streptococcus pneumoniae Rx1

55.556

95.625

0.531
  comX/comX1 Streptococcus pneumoniae Rx1

55.556

95.625

0.531
  comX/comX2 Streptococcus pneumoniae D39

55.556

95.625

0.531
  comX/comX2 Streptococcus pneumoniae R6

55.556

95.625

0.531
  comX/comX2 Streptococcus pneumoniae TIGR4

54.487

97.5

0.531
  comX/comX1 Streptococcus pneumoniae TIGR4

54.487

97.5

0.531
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

54.487

97.5

0.531
  comX/sigX Streptococcus mutans UA159

49.682

98.125

0.488
  comX/sigX Streptococcus suis D9

46.452

96.875

0.45
  comX/sigX Streptococcus suis isolate S10

46.452

96.875

0.45
  comX/sigX Streptococcus suis P1/7

46.452

96.875

0.45
  comX Streptococcus salivarius SK126

43.506

96.25

0.419
  comX/sigX Streptococcus salivarius strain HSISS4

42.857

96.25

0.412
  comX Streptococcus thermophilus LMG 18311

42.857

96.25

0.412
  comX Streptococcus thermophilus LMD-9

42.857

96.25

0.412
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

41.401

98.125

0.406
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

41.401

98.125

0.406
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

41.401

98.125

0.406
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

41.401

98.125

0.406
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

41.401

98.125

0.406
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

41.401

98.125

0.406
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.103

97.5

0.381
  comX Streptococcus sobrinus strain NIDR 6715-7

37.419

96.875

0.362