Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   I6J12_RS09840 Genome accession   NZ_CP068060
Coordinates   2049378..2049851 (+) Length   157 a.a.
NCBI ID   WP_020999414.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 2049910..2050863 2049378..2049851 flank 59


Gene organization within MGE regions


Location: 2049378..2050863
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS09840 (I6J12_09840) comR/comR2 2049378..2049851 (+) 474 WP_020999414.1 sigma-70 family RNA polymerase sigma factor Regulator
  I6J12_RS09845 (I6J12_09845) - 2049910..2050863 (-) 954 WP_003034583.1 IS30 family transposase -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19214.03 Da        Isoelectric Point: 6.2636

>NTDB_id=526821 I6J12_RS09840 WP_020999414.1 2049378..2049851(+) (comR/comR2) [Streptococcus anginosus strain FDAARGOS_1155]
MEFKELYAKVRGIVLKCCREYYVHLWELSDWDQEGMLVLYQLVSQYPQLVEEESQLYVYYKTKFRNHILDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDQLKSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide


Download         Length: 474 bp        

>NTDB_id=526821 I6J12_RS09840 WP_020999414.1 2049378..2049851(+) (comR/comR2) [Streptococcus anginosus strain FDAARGOS_1155]
ATGGAGTTCAAGGAGTTATATGCCAAGGTGAGAGGAATTGTACTAAAGTGCTGTCGGGAATATTATGTCCACCTGTGGGA
GTTAAGTGATTGGGACCAAGAGGGAATGTTGGTGCTCTATCAGTTGGTAAGCCAGTATCCGCAGCTGGTAGAAGAAGAAA
GTCAGCTCTATGTTTACTATAAGACCAAGTTCCGGAATCATATCCTGGACATCCTCCGTAAACAGGAAAGTCAAAAACGC
AAACTTGATCGTCAAGCTTATGAAGAAGTGAGCGAGATTGGTCACAAGCTCAGCCTAAAAGAACTATATCTGGATGAATT
GGTGATTCTCCGAGACCAGCTAAAGAGCTATCAAGCTCAACTGAGCCCAGAGAAACAGGAGCAGTACGAGCGCTTACTAG
CCGATGAACGGTTCAAAGGCCGCCAAGCTATGATTCGAGAATTAAGAGCCTACTTAAAAGATTATAGTGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

53.896

98.089

0.529
  comX/comX2 Streptococcus pneumoniae Rx1

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae Rx1

53.247

98.089

0.522
  comX/comX2 Streptococcus pneumoniae D39

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae D39

53.247

98.089

0.522
  comX/comX2 Streptococcus pneumoniae R6

53.247

98.089

0.522
  comX/comX1 Streptococcus pneumoniae R6

53.247

98.089

0.522
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

53.247

98.089

0.522
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

52.597

98.089

0.516
  comX/comX2 Streptococcus pneumoniae TIGR4

52.597

98.089

0.516
  comX/comX1 Streptococcus pneumoniae TIGR4

52.597

98.089

0.516
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

52.597

98.089

0.516
  comX/sigX Streptococcus mutans UA159

48.718

99.363

0.484
  comX/sigX Streptococcus suis D9

47.742

98.726

0.471
  comX/sigX Streptococcus suis isolate S10

47.742

98.726

0.471
  comX/sigX Streptococcus suis P1/7

47.742

98.726

0.471
  comX Streptococcus salivarius SK126

44.156

98.089

0.433
  comX/sigX Streptococcus salivarius strain HSISS4

43.506

98.089

0.427
  comX Streptococcus thermophilus LMG 18311

43.506

98.089

0.427
  comX Streptococcus thermophilus LMD-9

43.506

98.089

0.427
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.308

99.363

0.42
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

42.308

99.363

0.42
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.308

99.363

0.42
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.821

99.363

0.376
  comX Streptococcus sobrinus strain NIDR 6715-7

38.562

97.452

0.376