Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   I6H74_RS00115 Genome accession   NZ_CP066069
Coordinates   22424..22897 (-) Length   157 a.a.
NCBI ID   WP_115256744.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 17424..27897
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS00085 (I6H74_00085) - 17464..18309 (+) 846 WP_046177406.1 mechanosensitive ion channel family protein -
  I6H74_RS00090 (I6H74_00090) - 18372..18935 (-) 564 WP_022554238.1 TIGR01440 family protein -
  I6H74_RS00095 (I6H74_00095) - 18946..19419 (-) 474 WP_003054849.1 ECF transporter S component -
  I6H74_RS00100 (I6H74_00100) - 19406..20173 (-) 768 WP_049519880.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  I6H74_RS00105 (I6H74_00105) truA 20163..20912 (-) 750 WP_003054840.1 tRNA pseudouridine(38-40) synthase TruA -
  I6H74_RS00110 (I6H74_00110) - 21058..22407 (+) 1350 WP_115256745.1 aspartate kinase -
  I6H74_RS00115 (I6H74_00115) comX/sigX/comX2/sigX2 22424..22897 (-) 474 WP_115256744.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 18607.40 Da        Isoelectric Point: 9.0815

>NTDB_id=517072 I6H74_RS00115 WP_115256744.1 22424..22897(-) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MSLETGEVFEKVKPIILKLKRHYYLQLWETDDWLQEGHLVLVKLLERHPELVGDEARLYRYFKTKFSSYLKDVLRRQESQ
KRQFDKMAYEEIGDVAHAIPAGGLWLDDYVAYREVLVQVEEALSEADRKQFQALVRGERFKGRQALLRKVRPYFSGG

Nucleotide


Download         Length: 474 bp        

>NTDB_id=517072 I6H74_RS00115 WP_115256744.1 22424..22897(-) (comX/sigX/comX2/sigX2) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGTCGTTAGAGACAGGGGAGGTTTTTGAGAAGGTCAAACCTATTATTTTAAAGCTGAAGCGTCATTATTACTTACAGTT
GTGGGAGACGGATGACTGGTTACAAGAGGGGCATTTGGTTTTAGTGAAGTTGTTGGAACGTCACCCAGAGTTAGTAGGAG
ATGAGGCTCGCTTGTATCGGTATTTTAAAACCAAGTTTTCGTCGTATTTGAAAGATGTCTTGCGTCGGCAAGAAAGTCAG
AAACGCCAGTTTGACAAGATGGCTTATGAGGAGATAGGGGATGTGGCGCATGCGATTCCAGCTGGCGGGTTATGGTTGGA
TGATTATGTGGCCTATCGGGAGGTTTTAGTACAAGTGGAGGAGGCCTTAAGTGAAGCGGATCGGAAGCAGTTTCAGGCCT
TAGTGAGAGGGGAACGGTTCAAGGGGCGTCAGGCTTTGCTTAGGAAGGTTCGTCCTTACTTTAGTGGGGGATAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

75.974

98.089

0.745
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

75.974

98.089

0.745
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

75.325

98.089

0.739
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

75.325

98.089

0.739
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

74.675

98.089

0.732
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

74.675

98.089

0.732
  comX/sigX Streptococcus mutans UA159

50

94.268

0.471
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.649

94.268

0.459
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

46.622

94.268

0.439
  comX/comX1 Streptococcus pneumoniae Rx1

45.27

94.268

0.427
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

45.27

94.268

0.427
  comX/comX2 Streptococcus pneumoniae TIGR4

45.27

94.268

0.427
  comX/comX1 Streptococcus pneumoniae TIGR4

45.27

94.268

0.427
  comX/comX2 Streptococcus pneumoniae Rx1

45.27

94.268

0.427
  comX/comX2 Streptococcus pneumoniae D39

45.27

94.268

0.427
  comX/comX1 Streptococcus pneumoniae D39

45.27

94.268

0.427
  comX/comX2 Streptococcus pneumoniae R6

45.27

94.268

0.427
  comX/comX1 Streptococcus pneumoniae R6

45.27

94.268

0.427
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

45.833

91.72

0.42
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

45.833

91.72

0.42
  comX Streptococcus sobrinus strain NIDR 6715-7

44.218

93.631

0.414
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

43.919

94.268

0.414
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

43.243

94.268

0.408
  comX Streptococcus thermophilus LMD-9

44.444

91.72

0.408
  comX Streptococcus thermophilus LMG 18311

44.444

91.72

0.408
  comX/sigX Streptococcus salivarius strain HSISS4

42.361

91.72

0.389
  comX Streptococcus salivarius SK126

42.361

91.72

0.389
  comX/sigX Streptococcus suis D9

38.816

96.815

0.376
  comX/sigX Streptococcus suis isolate S10

39.597

94.904

0.376
  comX/sigX Streptococcus suis P1/7

39.597

94.904

0.376