Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   I6H78_RS04325 Genome accession   NZ_CP066059
Coordinates   906350..906823 (-) Length   157 a.a.
NCBI ID   WP_061853368.1    Uniprot ID   A0A139QWN8
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 901350..911823
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS04325 (I6H78_04325) comX/comX2 906350..906823 (-) 474 WP_061853368.1 hypothetical protein Regulator
  I6H78_RS04330 (I6H78_04330) nusG 906944..907480 (-) 537 WP_000376728.1 transcription termination/antitermination protein NusG -
  I6H78_RS04335 (I6H78_04335) secE 907538..907714 (-) 177 WP_000505776.1 preprotein translocase subunit SecE -
  I6H78_RS04340 (I6H78_04340) rpmG 907724..907876 (-) 153 WP_001809375.1 50S ribosomal protein L33 -
  I6H78_RS04345 (I6H78_04345) pbp2a 907929..910124 (-) 2196 WP_198460180.1 penicillin-binding protein PBP2A -
  I6H78_RS04350 (I6H78_04350) - 910211..911086 (+) 876 WP_332836293.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19291.12 Da        Isoelectric Point: 7.8480

>NTDB_id=516954 I6H78_RS04325 WP_061853368.1 906350..906823(-) (comX/comX2) [Streptococcus oralis strain FDAARGOS_1021]
MNLKDLYEESKGIVHKCRKDYHLHLWEKEDWDQEGMLCLYELVSRNPELLEGDRHQLYVCFKTKFRNRILDYIRKQESHK
RRFDKEPYEEVSEISHRLGEKGLRLDDYYLFHELLKNYKSKQSMEKQELIDRLMGGEVFRGRKALLRELSLIFSEFR

Nucleotide


Download         Length: 474 bp        

>NTDB_id=516954 I6H78_RS04325 WP_061853368.1 906350..906823(-) (comX/comX2) [Streptococcus oralis strain FDAARGOS_1021]
ATGAATCTAAAAGACTTATATGAAGAAAGTAAAGGAATCGTCCATAAGTGTCGCAAAGATTATCATTTGCATCTGTGGGA
GAAAGAGGACTGGGACCAGGAAGGCATGTTATGTCTGTATGAGCTGGTGAGTCGCAACCCAGAGTTACTAGAGGGCGACC
GCCATCAACTATATGTTTGCTTTAAAACAAAGTTTAGAAATCGCATCCTAGATTACATCCGTAAACAGGAAAGCCACAAG
CGCCGTTTTGACAAAGAACCCTATGAAGAGGTGAGTGAGATTAGCCATCGTCTAGGAGAAAAAGGACTCAGACTGGACGA
TTATTATCTCTTTCACGAACTTCTAAAGAATTATAAATCAAAGCAGAGTATGGAAAAACAAGAGTTAATAGATCGTCTCA
TGGGAGGGGAAGTCTTTAGAGGACGTAAAGCTCTCCTGAGAGAACTTTCCCTAATCTTTTCAGAATTTCGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139QWN8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

64.935

98.089

0.637
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

64.935

98.089

0.637
  comX/comX2 Streptococcus pneumoniae D39

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae D39

64.935

98.089

0.637
  comX/comX2 Streptococcus pneumoniae R6

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae R6

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae Rx1

64.935

98.089

0.637
  comX/comX1 Streptococcus pneumoniae TIGR4

64.286

98.089

0.631
  comX/comX2 Streptococcus pneumoniae TIGR4

64.286

98.089

0.631
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

63.636

98.089

0.624
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

63.636

98.089

0.624
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

63.636

98.089

0.624
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comX/sigX Streptococcus mutans UA159

47.368

96.815

0.459
  comX/sigX Streptococcus suis D9

40.764

100

0.408
  comX/sigX Streptococcus suis isolate S10

40.764

100

0.408
  comX/sigX Streptococcus suis P1/7

40.764

100

0.408
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.103

99.363

0.389
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.103

99.363

0.389
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

39.103

99.363

0.389
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

39.103

99.363

0.389
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

39.103

99.363

0.389
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

39.103

99.363

0.389
  comX/sigX Streptococcus salivarius strain HSISS4

40.667

95.541

0.389
  comX Streptococcus thermophilus LMG 18311

40.667

95.541

0.389
  comX Streptococcus thermophilus LMD-9

40.667

95.541

0.389
  comX Streptococcus salivarius SK126

40.667

95.541

0.389
  comX Streptococcus sobrinus strain NIDR 6715-7

42.657

91.083

0.389
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

36.709

100

0.369