Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   I6G43_RS00900 Genome accession   NZ_CP065706
Coordinates   194363..194836 (+) Length   157 a.a.
NCBI ID   WP_001049384.1    Uniprot ID   A0A7T3DV60
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 189363..199836
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS00885 (I6G43_00885) tilS 190445..191719 (+) 1275 WP_038805926.1 tRNA lysidine(34) synthetase TilS -
  I6G43_RS00890 (I6G43_00890) hpt 191728..192270 (+) 543 WP_000889396.1 hypoxanthine phosphoribosyltransferase -
  I6G43_RS00895 (I6G43_00895) ftsH 192286..194244 (+) 1959 WP_000744575.1 ATP-dependent zinc metalloprotease FtsH -
  I6G43_RS00900 (I6G43_00900) comX/comX2 194363..194836 (+) 474 WP_001049384.1 hypothetical protein Regulator

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19193.98 Da        Isoelectric Point: 7.7603

>NTDB_id=513186 I6G43_RS00900 WP_001049384.1 194363..194836(+) (comX/comX2) [Streptococcus oralis strain FDAARGOS_886]
MNLKELYEESKGIVNKCRKEYHLHLWEKEDWDQEGMMCLYELVNQHPELLEGERRQLYVCFKTKFRNRILDYIRKQESHK
RRFDKEPYEEVSEISHRLGEKGLRLDDYYLFHELLKNYKASQSKEKQEQLDRLMGGECFKGRKALLGELRVVLSDFR

Nucleotide


Download         Length: 474 bp        

>NTDB_id=513186 I6G43_RS00900 WP_001049384.1 194363..194836(+) (comX/comX2) [Streptococcus oralis strain FDAARGOS_886]
ATGAATCTGAAAGAACTATACGAAGAAAGTAAAGGGATTGTAAACAAGTGCCGCAAAGAATACCATTTACATCTGTGGGA
GAAAGAGGACTGGGACCAGGAGGGGATGATGTGCCTGTATGAGCTAGTGAACCAGCATCCAGAGTTACTAGAGGGCGAGC
GCCGTCAACTATATGTCTGCTTTAAAACCAAATTCCGCAATCGCATCCTAGACTACATCCGTAAACAGGAAAGTCACAAG
CGCCGTTTCGACAAAGAGCCTTATGAGGAGGTGAGCGAAATCAGTCATCGCCTAGGAGAAAAAGGCCTGAGACTGGATGA
TTACTATCTCTTTCATGAGCTTCTAAAGAATTACAAGGCAAGTCAGAGTAAAGAAAAACAAGAACAACTTGACCGTCTAA
TGGGAGGAGAATGTTTCAAAGGACGCAAGGCACTTCTAGGAGAATTAAGAGTGGTATTGAGTGATTTTAGATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T3DV60

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

63.636

98.089

0.624
  comX/comX2 Streptococcus pneumoniae D39

63.636

98.089

0.624
  comX/comX1 Streptococcus pneumoniae D39

63.636

98.089

0.624
  comX/comX2 Streptococcus pneumoniae R6

63.636

98.089

0.624
  comX/comX1 Streptococcus pneumoniae R6

63.636

98.089

0.624
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

63.636

98.089

0.624
  comX/comX1 Streptococcus pneumoniae Rx1

63.636

98.089

0.624
  comX/comX2 Streptococcus pneumoniae TIGR4

62.987

98.089

0.618
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

62.987

98.089

0.618
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

62.987

98.089

0.618
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

62.987

98.089

0.618
  comX/comX1 Streptococcus pneumoniae TIGR4

62.987

98.089

0.618
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

53.846

99.363

0.535
  comX/sigX Streptococcus mutans UA159

48.026

96.815

0.465
  comX/sigX Streptococcus suis isolate S10

44.586

100

0.446
  comX/sigX Streptococcus suis D9

44.586

100

0.446
  comX/sigX Streptococcus suis P1/7

44.586

100

0.446
  comX Streptococcus thermophilus LMD-9

42

95.541

0.401
  comX Streptococcus thermophilus LMG 18311

42

95.541

0.401
  comX Streptococcus salivarius SK126

41.333

95.541

0.395
  comX/sigX Streptococcus salivarius strain HSISS4

41.333

95.541

0.395
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

38.462

99.363

0.382
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

38.462

99.363

0.382
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.975

100

0.382
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

95.541

0.382
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

95.541

0.382
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

95.541

0.382
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

95.541

0.382
  comX Streptococcus sobrinus strain NIDR 6715-7

41.259

91.083

0.376