Detailed information NTG0050957

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: D7S_RS03880
• Genome accession: NC_017846
• Coordinates: 809245..810363 (-)
• Length: 372 a.a.
• NCBI ID: WP_005540807.1
• Uniprot ID: A0A142FZH0
• Organism: Aggregatibacter actinomycetemcomitans D7S-1
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 804245..815363

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D7S_RS03865 (D7S_00843)	rlmB	805363..806100 (+)	738	WP_005540800.1	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	-
D7S_RS03870 (D7S_00845)	glpT	806433..807875 (+)	1443	WP_005540804.1	glycerol-3-phosphate transporter	-
D7S_RS03875 (D7S_00846)	glpQ	808107..809189 (+)	1083	WP_014702339.1	glycerophosphodiester phosphodiesterase	-
D7S_RS03880 (D7S_00847)	dprA	809245..810363 (-)	1119	WP_005540807.1	DNA-processing protein DprA	Machinery gene
D7S_RS03885 (D7S_00848)	rplI	810581..811030 (-)	450	WP_005549026.1	50S ribosomal protein L9	-
D7S_RS03890 (D7S_00849)	rpsR	811046..811276 (-)	231	WP_005541294.1	30S ribosomal protein S18	-
D7S_RS03895 (D7S_02905)	priB	811289..811615 (-)	327	WP_005549024.1	primosomal replication protein N	-
D7S_RS03900 (D7S_00852)	rpsF	811602..811979 (-)	378	WP_005541284.1	30S ribosomal protein S6	-
D7S_RS03905 (D7S_00853)	lexA	812131..812754 (-)	624	WP_005541282.1	transcriptional repressor LexA	-

Sequence

Protein

• Length: 372 a.a.
• Molecular weight: 41696.85 Da
• Isoelectric Point: 6.4278

>NTDB_id=50957 D7S_RS03880 WP_005540807.1 809245..810363(-) (dprA) [Aggregatibacter actinomycetemcomitans D7S-1]
MNKHLALLLRLLQIPKLGPTTIHKILAQVNLSELQYYDAAAFTQMGWNAQQIQAWFHPEQRYIEPALLWGEKEGNHILDY
FHPDYPELLKQIESAPPVLFVKGATSALSQQQIAIVGSRQCSSYGEYWAKYFATELTTNGFIITSGLALGIDGFCHQAAV
DLKQPTIAVLGSGLEEVYPAKHRKLAQNIIEHDGALVSEFFPLQPPIAENFPRRNRIISGLSLATLIIEATERSGSLITA
RYALEQNREIFALPGNIQSQFSQGCHKLIKQGAMLVENVEDILENLAPQMTWKKRPQNRPHFSAIRKTTSTSLPPPVTPS
HPELYNIIGYNPISADDLSTTLNLSIDQILIQLLELELQDLIISENGLYRRV

Nucleotide

• Length: 1119 bp

>NTDB_id=50957 D7S_RS03880 WP_005540807.1 809245..810363(-) (dprA) [Aggregatibacter actinomycetemcomitans D7S-1]
ATGAACAAACATTTAGCACTTTTACTGCGCCTATTACAAATCCCCAAATTAGGCCCCACCACAATCCATAAAATCCTTGC
TCAAGTGAATTTATCCGAATTGCAATATTACGACGCGGCTGCATTTACGCAAATGGGCTGGAACGCACAACAGATTCAAG
CATGGTTTCATCCGGAGCAGCGCTATATTGAACCGGCACTTTTATGGGGAGAGAAAGAAGGAAATCATATTCTTGATTAT
TTTCACCCTGATTATCCCGAATTATTAAAACAAATCGAAAGCGCACCGCCGGTATTGTTCGTCAAAGGCGCGACAAGTGC
GCTATCACAGCAACAAATCGCTATTGTCGGTAGCCGCCAATGTTCAAGTTATGGTGAATATTGGGCGAAATATTTTGCCA
CGGAATTAACCACCAACGGTTTCATCATTACCAGCGGGTTGGCGTTAGGCATTGATGGTTTCTGCCATCAGGCTGCGGTC
GATTTAAAACAACCGACCATCGCCGTTTTAGGCAGCGGACTGGAAGAAGTGTATCCCGCCAAACATCGCAAATTAGCGCA
GAATATTATTGAACATGATGGTGCGTTGGTTTCTGAATTTTTCCCGCTACAACCACCGATTGCCGAAAATTTTCCCCGCC
GCAATCGCATTATCAGCGGGTTATCATTAGCGACCTTAATTATTGAAGCCACCGAACGCAGCGGATCATTAATTACGGCA
CGCTATGCGTTAGAACAAAACAGAGAAATTTTTGCACTACCGGGCAATATTCAAAGCCAGTTCAGCCAAGGCTGCCATAA
GCTTATTAAACAAGGCGCAATGCTGGTCGAAAACGTGGAAGATATTTTAGAAAATCTTGCGCCACAAATGACATGGAAAA
AACGCCCGCAAAATCGACCGCACTTTTCCGCTATAAGGAAAACAACGTCCACCTCATTACCGCCTCCCGTCACGCCATCC
CACCCCGAGCTATACAATATTATTGGTTATAACCCGATAAGCGCAGATGATTTATCTACAACACTTAATCTGTCTATTGA
TCAAATTCTCATTCAATTGCTGGAGCTGGAATTACAGGATTTAATTATCAGTGAAAACGGATTATATCGGCGGGTTTGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

• DprA winged helix domain (DprA_WH) (311-365)

3D structure

• AlphaFold DB: A0A142FZH0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	63.564	100	0.642
dprA	Glaesserella parasuis strain SC1401	55.966	94.624	0.53
dprA	Vibrio campbellii strain DS40M4	44.293	98.925	0.438
dprA	Vibrio cholerae strain A1552	43.316	100	0.435
dprA	Legionella pneumophila strain ERS1305867	40.541	99.462	0.403