Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX   Type   Regulator
Locus tag   SSUA7_RS00080 Genome accession   NC_017622
Coordinates   15967..16437 (+) Length   156 a.a.
NCBI ID   WP_011921639.1    Uniprot ID   A0A123YDQ1
Organism   Streptococcus suis A7     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 13656..54847 15967..16437 within 0


Gene organization within MGE regions


Location: 13656..54847
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUA7_RS00075 (SSUA7_0015) ftsH 13656..15629 (+) 1974 WP_011921638.1 ATP-dependent zinc metalloprotease FtsH -
  SSUA7_RS00080 (SSUA7_0016) comX/sigX 15967..16437 (+) 471 WP_011921639.1 sigma-70 family RNA polymerase sigma factor Regulator
  SSUA7_RS00200 (SSUA7_0019) mreC 23880..24716 (+) 837 WP_011921640.1 rod shape-determining protein MreC -
  SSUA7_RS00205 (SSUA7_0020) mreD 24706..25221 (+) 516 WP_002935339.1 rod shape-determining protein MreD -
  SSUA7_RS00210 (SSUA7_0021) pcsB 25306..26562 (+) 1257 WP_014638880.1 peptidoglycan hydrolase PcsB -
  SSUA7_RS00215 (SSUA7_0022) - 26665..27633 (+) 969 WP_002935337.1 ribose-phosphate diphosphokinase -
  SSUA7_RS00220 (SSUA7_0023) - 27720..28898 (+) 1179 WP_011922532.1 pyridoxal phosphate-dependent aminotransferase -
  SSUA7_RS00225 (SSUA7_0024) recO 28885..29667 (+) 783 WP_002935335.1 DNA repair protein RecO -
  SSUA7_RS00230 (SSUA7_0025) plsX 29664..30671 (+) 1008 WP_011921644.1 phosphate acyltransferase PlsX -
  SSUA7_RS00235 (SSUA7_0026) - 30664..30912 (+) 249 WP_011921645.1 phosphopantetheine-binding protein -
  SSUA7_RS00240 (SSUA7_0027) purC 31030..31737 (+) 708 WP_011921646.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  SSUA7_RS00245 (SSUA7_0028) - 31750..35469 (+) 3720 WP_012774881.1 phosphoribosylformylglycinamidine synthase -
  SSUA7_RS00250 (SSUA7_0029) purF 35472..36926 (+) 1455 WP_011921648.1 amidophosphoribosyltransferase -
  SSUA7_RS00255 (SSUA7_0030) purM 36982..38004 (+) 1023 Protein_27 phosphoribosylformylglycinamidine cyclo-ligase -
  SSUA7_RS00260 (SSUA7_0031) purN 38001..38552 (+) 552 WP_011922533.1 phosphoribosylglycinamide formyltransferase -
  SSUA7_RS00265 (SSUA7_0032) purH 38562..40109 (+) 1548 WP_011921652.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase -
  SSUA7_RS00270 (SSUA7_0033) purD 40235..41497 (+) 1263 WP_011921653.1 phosphoribosylamine--glycine ligase -
  SSUA7_RS00275 (SSUA7_0034) purE 41523..42011 (+) 489 WP_011921654.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  SSUA7_RS00280 (SSUA7_0035) purK 41998..43077 (+) 1080 WP_012774883.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  SSUA7_RS00285 (SSUA7_0036) - 43121..43882 (+) 762 WP_011921656.1 hypothetical protein -
  SSUA7_RS00290 (SSUA7_0037) - 43955..45181 (+) 1227 WP_011922536.1 hypothetical protein -
  SSUA7_RS00295 (SSUA7_0038) purB 45183..46475 (+) 1293 WP_011921659.1 adenylosuccinate lyase -
  SSUA7_RS00300 (SSUA7_0040) - 47412..48140 (+) 729 WP_012774884.1 hypothetical protein -
  SSUA7_RS00305 (SSUA7_0041) - 48150..48728 (+) 579 WP_011921662.1 CPBP family intramembrane glutamic endopeptidase -
  SSUA7_RS00310 (SSUA7_0042) - 48743..49171 (+) 429 WP_014636188.1 Msa family membrane protein -
  SSUA7_RS00315 (SSUA7_0043) - 49164..50036 (+) 873 WP_011921665.1 ABC transporter ATP-binding protein -
  SSUA7_RS00320 (SSUA7_0044) - 50042..50815 (+) 774 WP_012775420.1 membrane protein -
  SSUA7_RS00325 (SSUA7_0045) - 50818..52530 (+) 1713 WP_012774887.1 ABC transporter ATP-binding protein -
  SSUA7_RS10535 (SSUA7_0046) - 52632..52805 (+) 174 WP_011921669.1 hypothetical protein -
  SSUA7_RS00330 (SSUA7_0047) ruvB 53100..54101 (+) 1002 WP_004195448.1 Holliday junction branch migration DNA helicase RuvB -
  SSUA7_RS00335 (SSUA7_0048) - 54101..54847 (+) 747 WP_011921670.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 156 a.a.        Molecular weight: 19099.01 Da        Isoelectric Point: 8.9059

>NTDB_id=49810 SSUA7_RS00080 WP_011921639.1 15967..16437(+) (comX/sigX) [Streptococcus suis A7]
MEFEKVYASVKGIVNKARKEFYIKLWDRDDWEQEGMMTLFELLEAQPWLVDEQVQLYCYFKVKFRNRIKDRIRKQESQKR
KFDRMPHEDIYELSHAIQSPGLINDELLMLRGALRDYRKNLSNDQLDKYEKLISGQCFNGRREMIRDLQIHLKDFR

Nucleotide


Download         Length: 471 bp        

>NTDB_id=49810 SSUA7_RS00080 WP_011921639.1 15967..16437(+) (comX/sigX) [Streptococcus suis A7]
ATGGAATTCGAAAAAGTGTACGCAAGCGTCAAAGGTATTGTAAACAAGGCTCGAAAAGAGTTTTACATTAAACTATGGGA
TCGAGATGATTGGGAACAAGAAGGAATGATGACCTTGTTTGAATTGTTGGAAGCTCAACCGTGGCTAGTTGATGAACAAG
TTCAATTATATTGTTATTTTAAAGTCAAGTTCAGAAATCGAATCAAAGATCGTATCCGCAAACAGGAAAGTCAAAAACGC
AAGTTTGACCGTATGCCACATGAAGATATTTACGAATTATCTCACGCAATACAATCACCGGGATTGATAAACGATGAATT
ATTAATGTTGAGAGGTGCCTTGAGAGATTATCGAAAAAATCTGAGCAATGATCAACTTGATAAATACGAAAAATTAATTA
GCGGACAATGTTTTAATGGTCGCCGTGAAATGATACGTGATTTACAAATTCATTTGAAAGACTTTCGCTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A123YDQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX Streptococcus suis isolate S10

100

100

1
  comX/sigX Streptococcus suis P1/7

100

100

1
  comX/sigX Streptococcus suis D9

99.359

100

0.994
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

49.032

99.359

0.487
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

49.032

99.359

0.487
  comX/comX1 Streptococcus pneumoniae TIGR4

46.358

96.795

0.449
  comX/comX2 Streptococcus pneumoniae TIGR4

46.358

96.795

0.449
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

45.752

98.077

0.449
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

45.098

98.077

0.442
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

45.098

98.077

0.442
  comX/comX1 Streptococcus pneumoniae Rx1

45.695

96.795

0.442
  comX/comX2 Streptococcus pneumoniae D39

45.695

96.795

0.442
  comX/comX1 Streptococcus pneumoniae D39

45.695

96.795

0.442
  comX/comX2 Streptococcus pneumoniae R6

45.695

96.795

0.442
  comX/comX1 Streptococcus pneumoniae R6

45.695

96.795

0.442
  comX/comX2 Streptococcus pneumoniae Rx1

45.695

96.795

0.442
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

44.444

98.077

0.436
  comX/sigX Streptococcus mutans UA159

43.226

99.359

0.429
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

40.645

99.359

0.404
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

40.645

99.359

0.404
  comX Streptococcus sobrinus strain NIDR 6715-7

40.523

98.077

0.397
  comX Streptococcus thermophilus LMG 18311

40.523

98.077

0.397
  comX Streptococcus thermophilus LMD-9

40.523

98.077

0.397
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

99.359

0.397
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

99.359

0.397
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

99.359

0.397
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

99.359

0.397
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.854

100

0.391
  comX Streptococcus salivarius SK126

39.869

98.077

0.391
  comX/sigX Streptococcus salivarius strain HSISS4

39.869

98.077

0.391

Multiple sequence alignment